Article
Chemistry, Analytical
Ting Chen, Min Zhang, Huili Ma, Caizhi Liao, Qiguo Zhong, Yao-Jen Tu, Yongming Zhang, Ran Cao, Xiaofeng Chen
Summary: In this study, a ratiometric fluorescence sensor MOF-808-TPY was successfully constructed for quantitative analysis of the fluoroquinolone antibacterial agent fleroxacin. The sensor exhibited decreased fluorescence intensity at 370 nm and enhanced fluorescence intensity at 440 nm in the presence of fleroxacin, allowing for selective analysis of fleroxacin.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Analytical
Ashwani Kumar, Won Hur, Gi Hun Seong, Pil Seok Chae
Summary: The widespread use of cyanide in industry leads to contamination of various effluents, posing an imminent threat to the environment and human health. In this study, naphthoquinolinedione and anthracenedione probes were prepared for selective detection of cyanide. The addition of cyanide to the probe solutions resulted in a color change, and the nucleophilic addition of cyanide to the probes was responsible for selective detection. Among all probes, probe 1 showed the lowest fluorescence-based limit of detection and maintained its performance in detecting cyanide in real samples.
ANALYTICA CHIMICA ACTA
(2023)
Article
Chemistry, Analytical
Sumita Subedi, Lok Nath Neupane, Hyeongseok Yu, Keun-Hyeung Lee
Summary: A highly selective ratiometric fluorescent chemodosimeter was synthesized for the detection of Hg2+, which showed remarkable detection properties including high selectivity and sensitivity, large fluorescent signal changes, and well-operation in aqueous solutions. The displacement reaction between phenylboronic acid and Hg2+ ions provided a covalent adduct of mercury ion, leading to significant fluorescent signal changes when aggregated in aqueous solution. With a low detection limit of 15.2 nM, nanomolar concentrations of Hg2+ could be successfully detected, providing a ratiometric fluorescent detection method for quantifying low levels of Hg2+ in groundwater and tap water samples.
SENSORS AND ACTUATORS B-CHEMICAL
(2021)
Article
Chemistry, Physical
Patitapaban Mohanty, Pragyan P. Dash, S. Naik, Rubi Behura, M. Mishra, H. Sahoo, Suban K. Sahoo, Aruna K. Barick, Bigyan R. Jali
Summary: A thiourea-based fluorescence chemosensor (L) was synthesized and used for selective detection of Hg2+, Ag+, and Au3+ ions in DMSO-H2O solution. The fluorescence intensity of L was enhanced upon addition of the metal ions due to complexation-induced inhibition of the photo-induced electron transfer process. The 1:1 binding stoichiometry between L and the metal ions was determined, and density functional theory calculations were performed to explain the binding modes. The sensor L showed high sensitivity and low detection limits for Hg2+, Ag+, and Au3+ ions, and it was successfully applied in detecting these ions in living cells and soil samples.
JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY A-CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Nannan Zhu, Junhong Xu, Qiujuan Ma, Yang Geng, Linke Li, Shuzhen Liu, Shuangyu Liu, Gege Wang
Summary: The determination of mercuric ions (Hg2+) in environmental and biological samples has attracted researchers' attention lately. In this study, a novel turn-on Hg2+ fluorescent probe utilizing a rhodamine derivative has been constructed, which can sensitively and selectively sense Hg2+. The probe shows reversible dual colorimetric and fluorescence sensing of Hg2+ through forming a 1:1 coordination complex with Hg2+.
Article
Chemistry, Analytical
Chao Wang, Xianhao Zhao, Kaiyu Wu, Shuyi Lv, Chunlei Zhu
Summary: Sensing temperature is crucial for understanding physiological and pathological processes. However, highly sensitive temperature sensing with organic fluorescent nanothermometers is challenging. In this study, a ratiometric fluorescent nanogel thermometer is developed to determine bactericidal temperature. The nanogel exhibits reversible spectral changes based on its hydrophilic-to-hydrophobic transition, and its emission intensity can be correlated to external temperature. The nanogel shows promise in predicting photothermal antibacterial effects and other temperature-related biological events.
Article
Chemistry, Physical
Taisheng Wang, Lei Shen, Haoxiang Wang, Na Zhang
Summary: Designing fluorescent sensors for selective detection of CN- in aqueous and even solid states is a challenge due to the aggregation-caused quenching (ACQ) effect. The novel fluorescent probe C-1 reported in this paper exhibited orange-red fluorescence with emission peak centered at 597nm in aqueous solution and solid state, making it a selective CN-sensor with sensitivity and detection limit of 5.97 x 10(-4) M-1 and 1.2 mu M respectively. The interactions between C-1 and CN- were confirmed by UV-visible and fluorescent measurements, and the H-1 NMR titration method demonstrated the detection mechanism.
JOURNAL OF MOLECULAR STRUCTURE
(2021)
Article
Chemistry, Physical
Yun-Han Yang, Xin Tao, Qiu-Lian Bao, Ju Yang, Li-Jiao Su, Jun-Tong Zhang, Yan Chen, Li-Juan Yang
Summary: This study presents a highly sensitive and selective fluorescence sensor based on a 3,3-dihydroxybenzidine/phosphate pillar[5]arene inclusion complex (DHB/PP5A IC) for the detection of Au3+ ions in water. The IC was prepared using a saturated solution method, which improved the water solubility of DHB. Characterization techniques such as NMR, NOESY, SEM, FT-IR, and XRD were used to investigate the inclusion behavior and stoichiometric ratio of DHB and PP5A. The DHB/PP5A IC exhibited rapid and selective fluorescence quenching of Au3+ ions with a low detection limit in pure water.
JOURNAL OF MOLECULAR LIQUIDS
(2023)
Article
Spectroscopy
Jie Zhao, Jiawei Zhang, Baojun Hu, Chunyu Gao, Zan Li, Zhiwei Sun, Jinmao You
Summary: A new ratiometric fluorescent probe (APS-NA) was designed and synthesized for the detection of mercury ions in the environment and multiple biological samples. The probe shows a large Stokes shift, high selectivity, high sensitivity and naked eye visualization.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2023)
Article
Chemistry, Analytical
Xue-Qing Cheng, Zhi-Hao Dai, Han-Xiao Gao, Qing-Shan Pan, Xiang-Juan Kong, Fang-Fang Shen, Shuang Wu
Summary: In this study, a simple dual-emission ratio fluorescence sensor was developed for the fluorescent and visual detection of Cu2+. The sensor showed high sensitivity and easy operation, and the concentration of Cu2+ could be conveniently reflected with a smartphone application.
MICROCHEMICAL JOURNAL
(2023)
Article
Chemistry, Multidisciplinary
Chen Lin, Lizan Jiang, Hongyu Cheng, Yinping Qin, Pengyan Wu, Yue Tang, Yang Liu, Xiaohui Yang, Jian Wang
Summary: Researchers have successfully designed a fluorescent material, Co-HIAT, based on a metal-organic framework, for highly selective and sensitive detection of lithium ions. The Co-HIAT exhibits dual-emission properties and enables ratiometric fluorescence detection of Li+ by measuring the ratio of fluorescence at 340 to 410 nm. This work represents a significant advancement in the field of MOFs for lithium ion detection.
ACS SUSTAINABLE CHEMISTRY & ENGINEERING
(2023)
Article
Chemistry, Physical
Hao Guo, Liping Peng, Ning Wu, Bingqing Liu, Mingyue Wang, Yuan Chen, Zhilan Pan, Yinsheng Liu, Wu Yang
Summary: A blue fluorescent Si/CDs material was synthesized successfully as a sensitive fluorescent sensor for detecting Hg2+ ions in water, showing excellent optical properties and stability. The material can emit bright blue fluorescence under UV light, with a linear decrease in emission intensity correlating with increasing Hg2+ concentration, and a detection limit of 26.7 nM.
COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS
(2022)
Article
Spectroscopy
Cheng-lu Zhang, Xiang-ling Li, Yan-hua Jiang, Yi-ning Zhang, Yan-xuan Xie, Yue-dong Sun, Cui Liu
Summary: A ratiometric fluorescent probe (NQ) based on FRET was designed and synthesized, which showed high sensitivity and selectivity in detecting ClO-. It had a fast response time and strong anti-interference effect. Moreover, NQ could be applied to detect ClO- in real water samples and living cell imaging.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Spectroscopy
Wen-Jing Fu, Zhi-Xin Peng, Ying Dai, Yu-Fan Yang, Jia-Yu Song, Weiqing Sun, Baomiao Ding, Hui-Wen Gu, Xiao-Li Yin
Summary: In this study, nitrogen doped carbon dots were synthesized and demonstrated potential application in detecting Hg2+. The method was successfully applied to determine Hg2+ in beverage samples, indicating the potential of NCDs-based sensor for real beverage samples detection.
SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY
(2022)
Article
Materials Science, Ceramics
Zili Li, Shujie Pang, Mao Wang, Miao Wu, Pengjun Li, Jinna Bai, Xudong Yang
Summary: A novel dual-emission photoluminescent nano-materials of carbon dots-copper nanoclusters (CDs-CuNCs) nano-composites have been prepared for sensitive detection of Hg2+. The color of the nano-composites changes from pink to blue with the addition of Hg2+, showing efficient and sensitive detection capabilities for a wide range of applications.
CERAMICS INTERNATIONAL
(2021)
Article
Biochemistry & Molecular Biology
Xin Guo, Chang-Xiang Liu, Yuan Lu, Ya-Wen Wang, Yu Peng
Summary: A novel two-site chemodosimeter (SWJT-4) based on fluorescein skeleton was designed and synthesized to detect diethyl chlorophosphate (DCP). It acts as a turn-on fluorescent probe for DCP in aqueous solution, exhibiting good selectivity and obvious color change. The two oxime groups of SWJT-4 initiate different reactions with DCP, forming a cyano group and an isoxazole ring, respectively.
Article
Biochemistry & Molecular Biology
Zhiyuan Zhuang, Zhenbiao Luo, Sichen Yao, Yawen Wang, Yu Peng
Summary: A short synthesis of racemic Sacidumlignan B was achieved for the first time, involving a formal reductive coupling and a subsequent Friedel-Crafts cyclization to construct the dihydronaphthalene skeleton of this natural product.
Article
Biochemistry & Molecular Biology
Chang-Xiang Liu, Shu-Yuan Xiao, Xiu-Lin Gong, Xi Zhu, Ya-Wen Wang, Yu Peng
Summary: A novel near-infrared (NIR) fluorescent probe, SWJT-9, was designed and synthesized for the detection of hypochlorite anion (ClO-), showing excellent NIR fluorescence response with a color change under visible light. SWJT-9 demonstrated high selectivity, low detection limit (24.7 nM), and rapid detection (within 2 minutes) for ClO-. The detection mechanism of SWJT-9 on ClO- was confirmed using H-1 NMR, MS spectrum, and density functional theory (DFT) calculations.
Article
Chemistry, Organic
Yang Zhou, Hai Xu, Qing-Xiu Li, Zong-Rui Hou, Ya-Wen Wang, Yu Peng
Summary: Based on the AIE and TICT mechanisms, a fluorescent probe SWJT-12 was designed for the detection of ClO- by using the C equivalent to N bond as a reactive group. The synthesized probe can react with ClO- in a high aqueous phase, showing a large Stokes shift (144 nm) and low biological toxicity. Its limit of detection was calculated to be 0.28 μM. Furthermore, SWJT-12 was successfully used for ratiometric imaging of the exogenous hypochlorite anion in living cells.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Lin-Yuan Zhang, Li-Jun Xu, Ya-Wen Wang, Yu Peng
Summary: In this study, a ferrocene derivative was synthesized in a one-step reaction from benzotriazole-1-yl-oxytripyrrolidino-phosphonium hexafluorophosphate and ferrocenecarboxylic acid. The structure of the synthesized compound was determined accurately using H-1 and C-13 NMR, and further confirmed by X-ray diffraction analysis of a single crystal.
Article
Biochemistry & Molecular Biology
Xue-Shuang Yu, Mao-Mei Zhu, Rui Zuo, Yu Peng, Ya-Wen Wang
Summary: A new turn-on probe, SWJT-20, based on isophorone fluorophore was synthesized for the detection of nerve agent mimic diethyl chlorophosphite (DCP). SWJT-20 exhibited rapid response to DCP within 2 s using UV-Vis or fluorescent spectra, accompanied by a noticeable change in solution color under visible or UV light, observable with the naked eye. The detection limit of SWJT-20 for DCP was as low as 8.3 nM, surpassing most reported fluorescent probes for DCP detection. Additionally, SWJT-20 enabled quantitative measurement of DCP through ratio changes in absorption spectra (A(427)/A(645)). Furthermore, facile paper sensors were developed based on SWJT-20, allowing colorimetric/fluorometric responses for visual detection. Notably, this probe also detected DCP vapor through gas diffusion experiments.
Article
Chemistry, Analytical
Wei Du, Xiu-Lin Gong, Yang Tian, Xi Zhu, Yu Peng, Ya-Wen Wang
Summary: In this study, a coumarin derivative, SWJT-14, was synthesized as a fluorescence probe to effectively distinguish Cys, Hcy, and GSH in aqueous solutions. The probe showed a lower detection limit for Cys, Hcy, and GSH compared to biothiols in cells. It reacted with biothiols to generate different products with distinct conjugated structures, and fluorescence and UV-Vis spectra were used for differentiation. The detection mechanism was confirmed by MS. SWJT-14 was successfully utilized in cellular experiments for the detection of both endogenous and exogenous biothiols.
Article
Chemistry, Organic
Hai Xu, Long-Zhou Xu, Rui-Ping Huai, Chen Zhang, Sheng-Nan Suo, Ya-Qian Li, Yu Peng, Ya-Wen Wang
Summary: Inspired by the synthetic method of benzoxazine derivatives and our previous research, a fluorescent probe (SWJT-6) was designed for formaldehyde detection based on the cyclization reaction. The synthetic SWJT-6 showed excellent colorimetric and ratiometric response to formaldehyde, and could be perfectly used as test strips to detect formaldehyde. In addition, SWJT-6 has been successfully applied in bioimaging of intracellular and lysosomal formaldehyde in both HeLa cells and zebrafish.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Xue-Shuang Yu, Rui Zuo, Ming-Ye Shuai, Xu Feng, Yu Peng, Ya-Wen Wang
Summary: A novel ratiometric and colorimetric probe (SWJT-16) based on the isophorone skeleton was synthesized for the detection of diethyl chlorophosphite (DCP), a mimic of nerve agent. SWJT-16 showed a significant emission shift (??(em) = 174 nm) and a remarkable color change from blue to yellow under visible light upon nucleophilic substitution reaction with DCP in DMF. These changes occurred within 6 seconds, faster than most reported ratiometric fluorescent probes for DCP. Furthermore, SWJT-16 was effectively used to monitor gaseous DCP.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Min Peng, Quan-Rong Du, Xue Yao, Chun-Ni Li, Yang Tian, Yu Peng, Ya-Wen Wang
Summary: A simple fluorescein derivative was synthesized as a fluorescent probe for detecting malondialdehyde (MDA). The probe achieved ring-opening of fluorescein and formation of a benzohydrazide derivative through a synergistic reaction. It exhibited high sensitivity and selectivity for MDA detection, and could quickly and visually detect MDA within 60 s using UV-vis and fluorescent modes. Moreover, the probe showed excellent performance in imaging MDA in living cells and bacteria.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Nai-Jie Lin, Huan Wu, Jing Peng, Shu-Han Yang, Rui Tan, Yu Peng, Ya-Wen Wang
Summary: A novel ratiometric probe SWJT-10 based on isophorone derivatives was successfully designed and synthesized for the detection of formaldehyde (FA). This probe exhibited significant ratiometric fluorescence response to FA in aqueous solution, with a blue shift from NIR (680 nm) to yellow light region (600 nm). It showed excellent selectivity, high sensitivity, and rapid response to FA (less than 5 s) due to a new recognition mechanism. Furthermore, SWJT-10 has been successfully applied for monitoring FA in living cells and zebrafish.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Organic
Yu-Qing Zhang, Zhi-Nan Kang, Jing-Jie Ming, Sheng-Nan Suo, Jia-Ling Kang, Hai Xu, Ya-Wen Wang, Yu Peng
Summary: A new fluorescent probe has been developed for relay detection of hypochlorite ions and viscosity.
ORGANIC & BIOMOLECULAR CHEMISTRY
(2023)
Article
Chemistry, Multidisciplinary
Hai Xu, Chen Zhang, Yu-Qing Zhang, Sheng-Nan Suo, Ya-Wen Wang, Yu Peng
Summary: A novel red-NIR probe (SWJT-8) has been developed for detecting acrolein using the Michael addition reaction. SWJT-8 exhibits unique advantages such as colorimetric discrimination, high selectivity, and the fastest response. This probe has been successfully applied to detect intracellular acrolein.
CHEMICAL COMMUNICATIONS
(2022)
Article
Chemistry, Organic
Zhen-Biao Luo, Ya-Wen Wang, Yu Peng
ORGANIC & BIOMOLECULAR CHEMISTRY
(2020)
Article
Chemistry, Multidisciplinary
Bao-Jun Wang, Rui-Juan Liu, Jianguo Fang, Ya-Wen Wang, Yu Peng
CHEMICAL COMMUNICATIONS
(2019)
