期刊
ORGANIC LETTERS
卷 12, 期 1, 页码 80-83出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol902360b
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资金
- Department of Science and Technology, Government of India
- Council of Scientific and Industrial Research, New Delhi
A highly enantioselective Friedel-Crafts alkylation of pyrroles with 2-enoylpyridine N-oxides catalyzed by chiral PYBOX-DIPH-Zn(II) complexes has been developed. The catalyst otters substantial substrate scope and furnished alkylated pyrroles in excellent yields (up to 99%) and enantioselectivities (up to >99% ee).
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