期刊
ORGANIC LETTERS
卷 12, 期 13, 页码 3014-3017出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol1010246
关键词
-
资金
- Ministerio de Educacion y Ciencia [CTQ2007-61462]
- Generalitat Valenciana [GVPRE/2008/013]
- Universidad de Valencia
- MEC for a Raman y Cajal
Chiral imino lactones derived from (R)-phenylglycinol containing an allyl- or propargyltrimethylsilyl group in the side chain readily cyclized in the presence of acidic reagents to afford spirocyclic compounds with high diastereoselectivity. Removal of the chiral auxiliary produced 2-substituted 1-aminocycloalkanecarboxylic acids, whereas further cyclizations by means of metathesis or hydroamination reactions led to bicyclic derivatives of pipecolic acid and proline.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据