期刊
ORGANIC LETTERS
卷 11, 期 20, 页码 4720-4723出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901855b
关键词
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资金
- National Science Foundation
- American Chemical Society
A titanium-catalyzed three-component coupling reaction can be used to generate tautomers of N-aryl-1,3-diimines. Simple treatment of these products with acetic acid leads to cyclization forming quinoline derivatives in a one-pot procedure. The primary amines employed can be substituted anilines, aminonaphthalenes, or even heterocyclic amines, which leads to a variety of fused-ring heterocyclic frameworks. The one-pot yields varied from 25-71% for the 18 examples presented in this study.
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