4.8 Article

Copper-Catalyzed Tandem Oxidation-Olefination Process

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ORGANIC LETTERS
卷 11, 期 1, 页码 41-44

出版社

AMER CHEMICAL SOC
DOI: 10.1021/ol802299d

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  1. NSERC (Canada)
  2. Canada Foundation for Innovation
  3. Universite de Montreal
  4. American Chemical Society Petroleum Research Fund

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A novel catalytic sequence aerobic oxidation-olefination has been developed. A single and inexpensive copper,catalyst provides a large range of olefins from alcohols In good to excellent yields. The reaction exhibits excellent functional group compatibility, and the nonbasic reaction conditions allow the transformation of chiral substrates without racemization.

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