期刊
ORGANIC LETTERS
卷 11, 期 14, 页码 3052-3055出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol901091f
关键词
-
资金
- University of Pennsylvania
- FAPESP (State of Sao Paulo Research Foundation)
- CNPq (National Counsel of Technological and Scientific Development)
The first application of enzymes as catalysts to obtain optically pure boron compounds is described. The kinetic resolution of boron-containing chiral alcohols via enantioselective transesterification catalyzed by lipases was studied. Aromatic, allylic, and aliphatic secondary alcohols containing a boronate ester or boronic acid group were resolved by lipase from Candida antartica (CALB), and excellent E values (E > 200) and high enantiomeric excesses (up to >99%) of both remaining substrates and acetylated product were obtained.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据