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Mild, efficient Friedel-Crafts acylations from carboxylic acids using cyanuric chloride and AlCl3

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卷 10, 期 13, 页码 2645-2648

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AMER CHEMICAL SOC
DOI: 10.1021/ol800752v

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A mild method for Friedel-Crafts acylation with aromatic and aliphatic carboxylic acids using cyanuric chloride, pyridine, and AlCl(3) Was developed. Both inter- and intramolecular acylations were achieved at room temperature in high yield and in very short reaction times.

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