期刊
ORGANIC LETTERS
卷 10, 期 20, 页码 4489-4492出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol801708x
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资金
- GlaxoSmithKline
- CNRS
The marine natural product amphidinolide J has been synthesized according to a convergent strategy. The key steps of this synthesis include a B-alkyl Suzuki-Miyaura coupling and the addition of an alkynyllithium reagent to a Weinreb amide to build the C4-C5 and C12-C13 bonds, respectively, and a Yamaguchi macrolactonization.
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