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Escherichia coli glucuronylsynthase:: An engineered enzyme for the synthesis of β-glucuronides

ORGANIC LETTERS (2008)

期刊

ORGANIC LETTERS

卷 10, 期 8, 页码 1585-1588

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AMER CHEMICAL SOC

DOI: 10.1021/ol8002767

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Chemistry, Organic

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The glycosynthase derived from E coli beta-glucuronidase catalyzes the glucuronylation of a range of primary, secondary, and aryl alcohols with moderate to excellent yields. The procedure provides an efficient, stereoselective, and scalable single-step synthesis of 6-glucuronides under mild conditions.

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