期刊
ORGANIC LETTERS
卷 10, 期 19, 页码 4219-4222出版社
AMER CHEMICAL SOC
DOI: 10.1021/ol801566n
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资金
- The Netherlands Organization for Scientific Research (NWO-CW)
A highly efficient method is reported for the asymmetric conjugate addition of Grignard reagents to alpha,beta-unsaturated 2-pyridylsulfones. Using a Cu/TolBinap complex, excellent enantioselectivities and high yields are obtained for a wide variety of aliphatic substrates.
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