Preparation, anti-trypanosomal activity and localisation of a series of dipeptide-based vinyl sulfones

Chemical–biological characterization of a cruzain inhibitor reveals a second target and a mammalian off-target

(2013) Jonathan W Choy et al.   Beilstein Journal of Organic Chemistry

Fluorescent probes designed for detecting human serum albumin on the basis of its pseudo-esterase activity

(2013) Sung-Jean Kim et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of Rhodesain as a Novel Therapeutic Modality for Human African Trypanosomiasis

(2013) Roberta Ettari et al.   JOURNAL OF MEDICINAL CHEMISTRY

Vinyl Sulfone-Based Peptidomimetics as Anti-Trypanosomal Agents: Design, Synthesis, Biological and Computational Evaluation

(2013) Elizabeth Dunny et al.   JOURNAL OF MEDICINAL CHEMISTRY

NMR Studies of Protonation and Hydrogen Bond States of Internal Aldimines of Pyridoxal 5′-Phosphate Acid–Base in Alanine Racemase, Aspartate Aminotransferase, and Poly-l-lysine

(2013) Monique Chan-Huot et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Mapping Inhibitor Binding Modes on an Active Cysteine Protease via Nuclear Magnetic Resonance Spectroscopy

(2012) Gregory M. Lee et al.   BIOCHEMISTRY

Sensitivities of Some Imidazole-1-sulfonyl Azide Salts

(2012) Niko Fischer et al.   JOURNAL OF ORGANIC CHEMISTRY

Merging Constitutional and Motional Covalent Dynamics in Reversible Imine Formation and Exchange Processes

(2012) Petr Kovaříček et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

A Safe and Facile Route to Imidazole-1-sulfonyl Azide as a Diazotransfer Reagent

(2012) Hui Ye et al.   ORGANIC LETTERS

Proteomic profiling and potential cellular target identification of K11777, a clinical cysteine protease inhibitor, in Trypanosoma brucei

(2011) Peng-Yu Yang et al.   CHEMICAL COMMUNICATIONS

An Efficient, Inexpensive, and Shelf-Stable Diazotransfer Reagent: Imidazole-1-sulfonyl Azide Hydrochloride

(2011) Ethan D. Goddard-Borger et al.   ORGANIC LETTERS

Crystal Structures of TbCatB and Rhodesain, Potential Chemotherapeutic Targets and Major Cysteine Proteases of Trypanosoma brucei

(2010) Iain D. Kerr et al.   PLoS Neglected Tropical Diseases

Evolving Organic Synthesis Fostered by the Pluripotent Phenylsulfone Moiety

(2009) Ahmad El-Awa et al.   CHEMICAL REVIEWS

Chemical Tools To Study the Proteasome

(2009) Martijn Verdoes et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Vinyl Sulfones as Antiparasitic Agents and a Structural Basis for Drug Design

(2009) Iain D. Kerr et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Benzyne Click Chemistry: Synthesis of Benzotriazoles from Benzynes and Azides

(2008) Feng Shi et al.   ORGANIC LETTERS