期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 12, 期 4, 页码 643-650出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c3ob42020e
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资金
- National Science Foundation [NSF-21072080]
- National Basic Research Program of China (973 Program) [2010CB8-33203]
- 111 Project
- Program for Changjiang Scholars and innovative Research Team in University [IRT1138]
An intramolecular electrophilic ipso-iodocyclization of N-benzyl-N-(1-naphthyl)propiolamides combined with the Friedel-Crafts-type reaction for the synthesis of complex polycyclic lactams is reported. The resulting iodinated cyclization product can provide a very useful handle for further structural manipulation.
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