☆ 4.6 Article

An efficient organocatalytic enantioselective synthesis of spironitrocyclopropanes

ORGANIC & BIOMOLECULAR CHEMISTRY (2013)

期刊

ORGANIC & BIOMOLECULAR CHEMISTRY

卷 11, 期 1, 页码 44-47

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ROYAL SOC CHEMISTRY

DOI: 10.1039/c2ob26943k

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Chemistry, Organic

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National Science Council of the Republic of China [NSC 99-2119-M-003-004-MY2]
National Taiwan Normal University [NTNU100-D-06]

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摘要

An organocatalytic asymmetric synthesis of spironitrocyclopropanes has been demonstrated starting from 2-arylidene-1,3-indandiones and bromonitroalkanes catalyzed by a cinchona-derived bifunctional organocatalyst. The products were obtained with excellent enantioselectivities, diastereoselectivities and with good yields.

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