Conversion of a non-selective adenosine receptor antagonist into A3-selective high affinity fluorescent probes using peptide-based linkers

Adenosine receptors as drug targets — what are the challenges?

(2013) Jiang-Fan Chen et al.   NATURE REVIEWS DRUG DISCOVERY

Fragment Screening at Adenosine-A3 Receptors in Living Cells Using a Fluorescence-Based Binding Assay

(2012) Leigh A. Stoddart et al.   CHEMISTRY & BIOLOGY

Highly Potent and Selective Fluorescent Antagonists of the Human Adenosine A3 Receptor Based on the 1,2,4-Triazolo[4,3-a]quinoxalin-1-one Scaffold

(2012) Andrea J. Vernall et al.   JOURNAL OF MEDICINAL CHEMISTRY

Structure of the δ-opioid receptor bound to naltrindole

(2012) Sébastien Granier et al.   NATURE

Structure and dynamics of the M3 muscarinic acetylcholine receptor

(2012) Andrew C. Kruse et al.   NATURE

New insights from structural biology into the druggability of G protein-coupled receptors

(2012) Jonathan S. Mason et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Allosteric interactions across native adenosine-A3 receptor homodimers: quantification using single-cell ligand-binding kinetics

(2011) Lauren T. May et al.   FASEB JOURNAL

International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and Classification of Adenosine Receptors--An Update

(2011) B. B. Fredholm et al.   PHARMACOLOGICAL REVIEWS

New potent, short-linker BODIPY-630/650™ labelled fluorescent adenosine receptor agonists

(2011) Clare L. Dale et al.   MedChemComm

Influence of fluorophore and linker composition on the pharmacology of fluorescent adenosine A1 receptor ligands

(2010) Jillian G Baker et al.   BRITISH JOURNAL OF PHARMACOLOGY

A1 Receptors Ligands: Past, Present and Future Trends

(2010) S. Schenone et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

CF102 an A3 adenosine receptor agonist mediates anti-tumor and anti-inflammatory effects in the liver

(2010) S. Cohen et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Effect of Allosteric Modulators on the Kinetics of Agonist-G Protein-Coupled Receptor Interactions in Single Living Cells

(2010) L. T. May et al.   MOLECULAR PHARMACOLOGY

Structure of the Human Dopamine D3 Receptor in Complex with a D2/D3 Selective Antagonist

(2010) E. Y. T. Chien et al.   SCIENCE

 2-Adrenergic Receptor Redistribution in Heart Failure Changes cAMP Compartmentation

(2010) V. O. Nikolaev et al.   SCIENCE

Functionalized Congener Approach to the Design of Ligands for G Protein-Coupled Receptors (GPCRs)

(2009) Kenneth A. Jacobson   BIOCONJUGATE CHEMISTRY

Developments in fluorescent probes for receptor research

(2009) Marcello Leopoldo et al.   DRUG DISCOVERY TODAY

The Use of Amino Acid Linkers in the Conjugation of Paclitaxel with Hyaluronic Acid as Drug Delivery System: Synthesis, Self-Assembled Property, Drug Release, and In Vitro Efficiency

(2009) Dingcheng Xin et al.   PHARMACEUTICAL RESEARCH

The 2.6 Angstrom Crystal Structure of a Human A2A Adenosine Receptor Bound to an Antagonist

(2008) V.-P. Jaakola et al.   SCIENCE