Hybrids of amino acids and acetylenic DNA-photocleavers: optimising efficiency and selectivity for cancer phototherapy

Fine-tuning alkyne cycloadditions: Insights into photochemistry responsible for the double-strand DNA cleavage via structural perturbations in diaryl alkyne conjugates

(2011) Wang-Yong Yang et al.   Beilstein Journal of Organic Chemistry

Cyclizations of Alkynes: Revisiting Baldwin’s Rules for Ring Closure

(2011) Kerry Gilmore et al.   CHEMICAL REVIEWS

Engineering pH-Gated Transitions for Selective and Efficient Double-Strand DNA Photocleavage in Hypoxic Tumors

(2011) Wang-Yong Yang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Radical O→C Transposition: A Metal-Free Process for Conversion of Phenols into Benzoates and Benzamides

(2011) Abdulkader Baroudi et al.   JOURNAL OF ORGANIC CHEMISTRY

Wolff rearrangement of β-alkynyl-α-diazo-β-ketoesters: light-induced acetylene-allene isomerization and its use for activation of enediynes

(2011) Natalia G. Zhegalova et al.   JOURNAL OF PHYSICAL ORGANIC CHEMISTRY

Rules for Anionic and Radical Ring Closure of Alkynes

(2011) Igor V. Alabugin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization

(2010) Jonathan P. Celli et al.   CHEMICAL REVIEWS

Radical 1,2-O→C Transposition for Conversion of Phenols into Benzoates by O-Neophyl Rearrangement/Fragmentation Cascade

(2010) Abdulkader Baroudi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Metal-Free Transformation of Phenols into Substituted Benzamides: A Highly Selective Radical 1,2-O→C Transposition in O-Aryl-N-phenylthiocarbamates

(2010) Abdulkader Baroudi et al.   CHEMISTRY-A EUROPEAN JOURNAL

Photocytotoxicity and DNA cleavage activity of l-arg and l-lys Schiff base oxovanadium(iv) complexes having phenanthroline bases

(2010) Pijus K. Sasmal et al.   DALTON TRANSACTIONS

The C-terminal Lysine of Ogg2 DNA Glycosylases is a Major Molecular Determinant for Guanine/8-Oxoguanine Distinction

(2010) Frédérick Faucher et al.   JOURNAL OF MOLECULAR BIOLOGY

Bergman Cyclization of Acyclic Amino Acid Derived Enediynes Leads to the Formation of 2,3-Dihydrobenzo[f]isoindoles

(2010) Matija Gredičak et al.   JOURNAL OF ORGANIC CHEMISTRY

Memory of Chirality in Cascade Rearrangements of Enediynes

(2010) Malek Nechab et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

“Where, O Death, Is Thy Sting?” A Brief Review of Apoptosis Biology

(2010) Andrew H. Wyllie   MOLECULAR NEUROBIOLOGY

Rapid DNA-protein cross-linking and strand scission by an abasic site in a nucleosome core particle

(2010) J. T. Sczepanski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Design and synthesis of enediyne–peptide conjugates and their inhibiting activity against chymotrypsin

(2009) Sansa Dutta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Oligopyridine–ruthenium(ii)–amino acid conjugates: synthesis, characterization, DNA binding properties and interactions with the oligonucleotide duplex d(5′-CGCGCG-3′)2

(2009) Katelitsa Triantafillidi et al.   DALTON TRANSACTIONS

C-Lysine Conjugates: pH-Controlled Light-Activated Reagents for Efficient Double-Stranded DNA Cleavage with Implications for Cancer Therapy

(2009) Wang-Yong Yang et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Conformationally Gated Fragmentations and Rearrangements Promoted by Interception of the Bergman Cyclization through Intramolecular H-Abstraction: A Possible Mechanism of Auto-Resistance to Natural Enediyne Antibiotics?

(2009) Abdulkader Baroudi et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photoinduced DNA cleavage by fullerene–lysine conjugate

(2009) Anish Kumar et al.   TETRAHEDRON LETTERS

Design, synthesis and DNA-cleaving efficiency of photoswitchable dimeric azobenzene-based C2-symmetric enediynes

(2008) Amit Basak et al.   CHEMICAL COMMUNICATIONS

Towards Photoswitchable Enediyne Antibiotics: Single and Two-Photon Triggering of Bergman Cyclization

(2008) Andrei Polukhtine et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Enhancement of the Reactivity of Photochemically Generated Enediynes via Keto−Enol Tautomerization

(2008) Grigori Karpov et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

In Search of Efficient 5-Endo-dig Cyclization of a Carbon-Centered Radical: 40 Years from a Prediction to Another Success for the Baldwin Rules

(2008) Igor V. Alabugin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Thermal C1−C5Diradical Cyclization of Enediynes

(2008) Chandrasekhar Vavilala et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Radical Cascade Transformations of Tris(o-aryleneethynylenes) into Substituted Benzo[a]indeno[2,1-c]fluorenes

(2008) Igor V. Alabugin et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Photochemical Generation and Reversible Cycloaromatization of a Nine-Membered Ring Cyclic Enediyne

(2008) Dinesh R. Pandithavidana et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Synthesis and aromatisation of cyclic enediyne-containing amino acids

(2008) Jasper Kaiser et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

DNA−Protein Cross-links between Guanine and Lysine Depend on the Mechanism of Oxidation for Formation of C5 Vs C8 Guanosine Adducts

(2007) Xiaoyun Xu et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY