4.6 Article

Gold(I)-catalyzed intramolecular hydroamination and ring-opening of sulfonamide-substituted 2-(arylmethylene)cyclopropylcarbinols

期刊

ORGANIC & BIOMOLECULAR CHEMISTRY
卷 10, 期 18, 页码 3763-3766

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c2ob25512j

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资金

  1. Shanghai Municipal Committee of Science and Technology [11JC1402600]
  2. National Basic Research Program of China (973) [2010CB833302]
  3. National Natural Science Foundation of China [21072206, 20472096, 20872162, 20672127, 20732008, 21121062]

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An interesting gold(I)-catalyzed intramolecular hydroamination and ring-opening of sulfonamide-substituted 2-(arylmethylene)cyclopropylcarbinols has been described in this context. Avariety of 4-substituted isoxazolidine derivatives were obtained in good to high yields through a highly regioselective cleavage of a carbon-carbon single bond in the cyclopropane.

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