A chemoselective Ugi-type reaction in water using TMSCN as a functional isonitrile equivalent: generation of heteroaromatic molecular diversity

Skeletal Diverse Synthesis of N-Fused Polycyclic Heterocycles via the Sequence of Ugi-Type MCR and CuI-Catalyzed Coupling/Tandem Pictet–Spengler Reaction

(2012) Vikas Tyagi et al.   JOURNAL OF ORGANIC CHEMISTRY

CuSO4–Glucose for in Situ Generation of Controlled Cu(I)–Cu(II) Bicatalysts: Multicomponent Reaction of Heterocyclic Azine and Aldehyde with Alkyne, and Cycloisomerization toward Synthesis of N-Fused Imidazoles

(2012) Sankar K. Guchhait et al.   JOURNAL OF ORGANIC CHEMISTRY

A Bioinspired Ugi/Michael/Aza-Michael Cascade Reaction in Aqueous Media: Natural-Product-like Molecular Diversity

(2011) Soumava Santra et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Multicomponent Reaction Design in the Quest for Molecular Complexity and Diversity

(2011) Eelco Ruijter et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Expedient entry to the piperazinohydroisoquinoline ring system using a sequential Ugi/Pictet–Spengler/reductive methylation reaction protocol

(2011) Ma.-Angeles Cano-Herrera et al.   CHEMICAL COMMUNICATIONS

Green chemistry oriented organic synthesis in water

(2011) Marc-Olivier Simon et al.   CHEMICAL SOCIETY REVIEWS

N-Fused Imidazoles As Novel Anticancer Agents That Inhibit Catalytic Activity of Topoisomerase IIα and Induce Apoptosis in G1/S Phase

(2011) Ashish T. Baviskar et al.   JOURNAL OF MEDICINAL CHEMISTRY

A Rapid, One-Pot, Microwave-Influenced Synthesis of Spiro-2,5-diketopiperazines via a Cascade Ugi/6-Exo-TrigAza-Michael Reaction

(2011) Soumava Santra et al.   JOURNAL OF ORGANIC CHEMISTRY

ZnO nanorods as an efficient catalyst for the synthesis of imidazo[1,2-a]azines and diazines

(2011) Samahe Sadjadi et al.   MONATSHEFTE FUR CHEMIE

Robust Generation of Lead Compounds for Protein-Protein Interactions by Computational and MCR Chemistry: p53/Hdm2 Antagonists

(2010) Anna Czarna et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

General and Efficient Copper-Catalyzed Three-Component Coupling Reaction towards Imidazoheterocycles: One-Pot Synthesis of Alpidem and Zolpidem

(2010) Natalia Chernyak et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

1,4-Thienodiazepine-2,5-diones via MCR (II): Scaffold Hopping by Gewald and Ugi-Deprotection-Cyclization Strategy

(2010) Yijun Huang et al.   Chemical Biology & Drug Design

Seven-component reactions by sequential chemoselective Ugi–Mumm/Ugi–Smiles reactions

(2010) Sebastian Brauch et al.   CHEMICAL COMMUNICATIONS

Efficient Multicomponent Reaction Synthesis of the Schistosomiasis Drug Praziquantel

(2010) Haiping Cao et al.   CHEMISTRY-A EUROPEAN JOURNAL

The impact of aromatic ring count on compound developability: further insights by examining carbo- and hetero-aromatic and -aliphatic ring types

(2010) Timothy J. Ritchie et al.   DRUG DISCOVERY TODAY

Toward Pyrrolo[2,3-d]pyrimidine Scaffolds

(2010) Laurent El Kaïm et al.   JOURNAL OF ORGANIC CHEMISTRY

Towards molecular diversity: dealkylation of tert-butyl amine in Ugi-type multicomponent reaction product establishes tert-butyl isocyanide as a useful convertible isonitrile

(2010) Sankar K. Guchhait et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

One-Pot Syntheses of Chromeno[3,4-c]pyrrole-3,4-diones via Ugi-4CR and Intramolecular Michael Addition

(2010) Chao Che et al.   ORGANIC LETTERS

Novel One-Pot, Four-Component Condensation Reaction: An Efficient Approach for the Synthesis of 2,5-Disubstituted 1,3,4-Oxadiazole Derivatives by a Ugi-4CR/aza-Wittig Sequence

(2010) Ali Ramazani et al.   ORGANIC LETTERS

Concise Approach toward Tetrazolo[1,5-a][1,4]benzodiazepines via a Novel Multicomponent Isocyanide-Based Condensation

(2010) Roman S. Borisov et al.   ORGANIC LETTERS

DMAP-catalyzed cyanation of aldehydes and ketones with ethyl cyanoformate

(2010) Shohei Aoki et al.   TETRAHEDRON LETTERS

One-pot three-component synthesis of α-aminonitriles using potassium hexacyanoferrate(II) as an eco-friendly cyanide source

(2010) Zheng Li et al.   TETRAHEDRON LETTERS

Groebke–Blackburn–Bienaymé multicomponent reaction in scaffold-modification of adenine, guanine, and cytosine: synthesis of aminoimidazole-condensed nucleobases

(2010) Sankar K. Guchhait et al.   TETRAHEDRON LETTERS

Chemical space as a source for new drugs

(2010) Jean-Louis Reymond et al.   MedChemComm

Natural Product Synthesis Using Multicomponent Reaction Strategies

(2009) Barry B. Touré et al.   CHEMICAL REVIEWS

An Efficient, Regioselective, Versatile Synthesis of N-Fused 2- and 3-Aminoimidazoles via Ugi-Type Multicomponent Reaction Mediated by Zirconium(IV) Chloride in Polyethylene Glycol-400

(2009) Sankar Guchhait et al.   SYNLETT

A Highly Flexible and Efficient Ugi-Type Multicomponent Synthesis of Versatile N-Fused Aminoimidazoles

(2009) Sankar Guchhait et al.   SYNTHESIS-STUTTGART

Silica-sulfuric acid: a highly efficient catalyst for the synthesis of imidazo[1,2-a]pyridines using trimethysilyl cyanide or cyanohydrins

(2009) Anatoliy I. Polyakov et al.   TETRAHEDRON LETTERS

Biaryl Phosphane Ligands in Palladium-Catalyzed Amination

(2008) David S. Surry et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Isocyanide-based multicomponent reactions in drug discovery

(2008) Irini Akritopoulou-Zanze   CURRENT OPINION IN CHEMICAL BIOLOGY

Greater variety in Groebke–Blackburn type 3-arylaminoimidazo[1,2-a]azines accessed via Pd-catalyzed arylation of a primary amine precursor

(2008) Yuri Sandulenko et al.   TETRAHEDRON LETTERS