Computational design of a thermostable mutant of cocaine esterase via molecular dynamics simulations
出版年份 2011 全文链接
标题
Computational design of a thermostable mutant of cocaine esterase via molecular dynamics simulations
作者
关键词
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出版物
ORGANIC & BIOMOLECULAR CHEMISTRY
Volume 9, Issue 11, Pages 4138
出版商
Royal Society of Chemistry (RSC)
发表日期
2011-03-04
DOI
10.1039/c0ob00972e
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- (2010) Diwahar Narasimhan et al. PROTEIN ENGINEERING DESIGN & SELECTION
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- (2009) Karen Rutherford et al. BIOCHEMISTRY
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- (2009) Wenchao Yang et al. BIOPHYSICAL JOURNAL
- Effects of cocaine esterase following its repeated administration with cocaine in mice
- (2009) Mei-Chuan Ko et al. DRUG AND ALCOHOL DEPENDENCE
- Cold Adaptation of Zinc Metalloproteases in the Thermolysin Family from Deep Sea and Arctic Sea Ice Bacteria Revealed by Catalytic and Structural Properties and Molecular Dynamics
- (2009) Bin-Bin Xie et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Cocaine Esterase Prevents Cocaine-Induced Toxicity and the Ongoing Intravenous Self-Administration of Cocaine in Rats
- (2009) G. T. Collins et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Structure and Dynamics of Cold-Adapted Enzymes as Investigated by FT-IR Spectroscopy and MD. The Case of an Esterase fromPseudoalteromonas haloplanktis
- (2009) Vincenzo Aurilia et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Fundamental Reaction Mechanism and Free Energy Profile for (−)-Cocaine Hydrolysis Catalyzed by Cocaine Esterase
- (2009) Junjun Liu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Rational stabilization of enzymes by computational redesign of surface charge–charge interactions
- (2009) Alexey V. Gribenko et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Bacterial Cocaine Esterase Protects Against Cocaine-Induced Epileptogenic Activity and Lethality
- (2008) Emily M. Jutkiewicz et al. ANNALS OF EMERGENCY MEDICINE
- Macromolecular Modeling with Rosetta
- (2008) Rhiju Das et al. Annual Review of Biochemistry
- Computational Design of Calmodulin Mutants with up to 900-Fold Increase in Binding Specificity
- (2008) Eliyahu Yosef et al. JOURNAL OF MOLECULAR BIOLOGY
- Synthetic affinity ligands as a novel tool to improve protein stability
- (2008) I. T. Sousa et al. JOURNAL OF MOLECULAR RECOGNITION
- Flexibility of Human Cytochromes P450: Molecular Dynamics Reveals Differences between CYPs 3A4, 2C9, and 2A6, which Correlate with Their Substrate Preferences
- (2008) Josef Skopalík et al. JOURNAL OF PHYSICAL CHEMISTRY B
- Modeling the Catalysis of Anti-Cocaine Catalytic Antibody: Competing Reaction Pathways and Free Energy Barriers
- (2008) Yongmei Pan et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Most Efficient Cocaine Hydrolase Designed by Virtual Screening of Transition States
- (2008) Fang Zheng et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Thermostable Variants of Cocaine Esterase for Long-Time Protection against Cocaine Toxicity
- (2008) D. Gao et al. MOLECULAR PHARMACOLOGY
- Identifying stabilizing key residues in proteins using interresidue interaction energy matrix
- (2008) Lada Bendová-Biedermannová et al. PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
- Using a strategy based on the concept of convergent evolution to identify residue substitutions responsible for thermal adaptation
- (2008) Yeong-Shin Lin PROTEINS-STRUCTURE FUNCTION AND BIOINFORMATICS
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