Letter
Ophthalmology
Federico Zicarelli, Giovanni Staurenghi, Alessandro Invernizzi
Summary: Clinical grading of vitreous haze has limitations, while the use of Anterior Segment Optical Coherence Tomography (AS-OCT) imaging can provide an objective characterization of inflammatory changes in the anterior vitreous.
OCULAR IMMUNOLOGY AND INFLAMMATION
(2023)
Article
Ophthalmology
Fang Liu, Fei Xia, Lingling Niu, Jing Zhao, Xiaoying Wang, Xingtao Zhou
Summary: The study investigated early changes in circumferential anterior segment structures after ICL V4c implantation, providing a better understanding of the characteristics of anterior segment structures after ICL V4c surgery.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Medicine, General & Internal
Hiroshi Keino, Takuto Aman, Ryota Furuya, Makiko Nakayama, Annabelle A. Okada, Wataru Sunayama, Yuji Hatanaka
Summary: This study aimed to develop an automated method for evaluating anterior chamber (AC) cells in uveitis using optical coherence tomography (OCT) images. By analyzing the images with software and an automated algorithm, approximate AC grading values were obtained based on the correlation with Standardization of Uveitis Nomenclature (SUN) grading scores. The results showed significant correlations between the automated cellular spots analysis and the clinical scores, providing continuous AC grading values. This method improves the accuracy of quantitative assessment and allows objective and rapid evaluation of anterior segment inflammation in uveitis.
Article
Biochemical Research Methods
Steve Frisken, Trevor Anderson, Armin Segref, Dirk Lorenser, Grant Frisken
Summary: HP-OCT is a parallel spectral domain imaging technology that is well-suited for imaging the anterior segment of the eye. This study demonstrates that sparsely sampled volumes can be registered without active eye tracking to produce motion artifact-free 3D volumes. The anterior volume provides comprehensive 3D biometric information, including lens position, curvature, epithelial thickness, tilt, and axial length. Moreover, by changing a detachable lens, high-resolution anterior volumes and posterior volume images for preoperative assessment of the posterior segment can be captured. Importantly, the retinal volumes have the same Nyquist range as the anterior imaging mode.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Ophthalmology
Yukihito Kato, Takashi Kojima, Akeno Tamaoki, Kei Ichikawa, Kensei Tamura, Kazuo Ichikawa
Summary: The study evaluated the refractive error after cataract surgery using an optical biometer equipped with anterior segment optical coherence tomography (AS-OCT). The results showed significant differences between AS-OCT and OCT in various parameters, and AS-OCT exhibited significantly larger refractive prediction error than OCT in all three formulas. This suggests that the two methods could lead to meaningful differences in intraocular lens selection.
JOURNAL OF CATARACT AND REFRACTIVE SURGERY
(2022)
Article
Ophthalmology
Martin Arman Sorkhabi, Ivan O. Potapenko, Tomas Ilginis, Mark Alberti, Javier Cabrerizo
Summary: This study developed an automated AI-based method to quantify inflammation in the anterior chamber (AC) using AS-OCT and found a significant correlation between AI-assisted AS-OCT based inflammation analysis and clinical grading of anterior uveitis. The AI software accurately segmented AC boundaries and detected particles within the AC borders, showing potential application in early detection and management of anterior uveitis.
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2022)
Article
Ophthalmology
Stefan Georgiev, Manuel Ruiss, Andreea Dana-Fisus, Rainer A. Leitgeb, Oliver Findl
Summary: This study compared the corneal aberrations measured by two different ophthalmic devices in elderly cataract patients and found that there was a certain agreement between the two devices. However, caution should be exercised when interpreting higher order aberration parameters for surgical decision-making.
Article
Multidisciplinary Sciences
Yun Jeong Lee, Sukkyu Sun, Young Kook Kim
Summary: This study aims to predict demographic characteristics from AS-OCT images of the eyeball using a deep learning model, and assess the importance of specific anterior segment areas. A large-scale, retrospective cross-sectional study will be conducted using a clinical data warehouse to collect AS-OCT images and demographic characteristics. A Vision Transformer model will be built for prediction, and the regions in the AS-OCT images that contribute to the model's decisions will be visualized. Model performance will be evaluated using accuracy, sensitivity, specificity, and AUC.
Article
Engineering, Biomedical
Pedro Tana-Sanz, Maria Ruiz-Santos, Maria Dolores Rodriguez-Carrillo, Salvador Aguilar-Corcoles, Robert Montes-Mico, Pedro Tana-Rivero
Summary: The study evaluated the agreement of different biometric parameters obtained using intraoperative spectral-domain optical coherence tomography (SD-OCT) and two swept-source optical coherence tomography (SS-OCT) based biometers. Results showed that SS-OCT biometers demonstrated good agreement for anterior chamber depth (ACD), central corneal thickness (CCT), white-to-white (WTW) and lens thickness (LT), while SD-OCT showed discrepancies in ACD, CCT, and WTW values compared to SS-OCT biometers, but excellent agreement in LT measurements.
EXPERT REVIEW OF MEDICAL DEVICES
(2021)
Article
Biology
Sara Ortiz-Toquero, Carlota Fuente, Clara Auladell, Francisco Arnalich-Montiel
Summary: In order to determine consistent change over time in keratoconus disease, this study analyzed the accuracy of corneal parameters using Scheimpflug tomography and anterior segment optical coherence tomography. The results showed that the Casia device presented better repeatability and reproducibility compared to the Pentacam. The cut-off values for indicating real progressive in keratoconus varied depending on the severity of the disease.
Article
Biochemical Research Methods
Marco Ruggeri, Giulia Belloni, Yu-Cherng Chang, Heather Durkee, Ettore Masetti, Florence Cabot, Sonia H. Yoo, Arthur Ho, Jean-Marie Parel, Fabrice Manns
Summary: The system combines AS-OCT and a wavefront-based aberrometer to continuously and in real-time acquire OCT images and refractive error measurements. It measures refractive error with accuracy and precision comparable to clinical autorefractors, suitable for guiding cataract surgery or simultaneous autorefraction and ocular biometry.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Biochemical Research Methods
Duardo Martinez-Enriquez, Andrea Curatolo, Alberto de Castro, Judith S. Birkenfeld, Ana M. Gonzalez, Ashik Mohamed, Marco Ruggeri, Fabrice Manns, Zvietcovich Fernando, Susana Marcos
Summary: In this study, we successfully estimated the full shape of the in vivo crystalline lens using the eigenlenses method, which only utilizes information visible through the pupil. Compared to previous methods, eigenlenses showed improved repeatability, robustness, and computational resource utilization in estimating crystalline lens shape. Eigenlenses can efficiently describe the full shape changes of the crystalline lens with accommodation and refractive error.
BIOMEDICAL OPTICS EXPRESS
(2023)
Review
Ophthalmology
Jeewan S. Titiyal, Manpreet Kaur, Sridevi Nair, Namrata Sharma
Summary: Intraoperative optical coherence tomography (iOCT) provides real-time visualization of ocular structures during surgery, aiding in decision-making and guidance for various anterior segment surgeries. Its efficacy and feasibility have been well established, particularly in lamellar keratoplasty and endothelial keratoplasty. iOCT also has applications in phacoemulsification, glaucoma surgeries, and pediatric patients, while ongoing technological advances aim to improve limitations related to instrument compatibility and real-time image analysis.
SURVEY OF OPHTHALMOLOGY
(2021)
Article
Biochemical Research Methods
Eduardo Martinez-Enriquez, Bianca Maceo Heilman, Alberto de Castro, Ashik Mohamed, Marco Ruggeri, Fermamdp Zvietcovich, Fabrice Manns, Susana Marcos
Summary: Quantifying the geometry of human crystalline lens as a function of age and accommodation is crucial for better treatments of cataract and presbyopia. This study validates the use of eigenlenses to estimate the full shape of dis-accommodated lenses in vivo. The results demonstrate that eigenlenses can accurately estimate the shape of dis-accommodated lenses.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Pharmacology & Pharmacy
A. C. Ormeci, S. Bayraktar, A. O. Isik, B. Cavus, R. Akas, Z. Istemihan, M. K. Saridal, F. Akyuz, F. Besisik, S. Kaymakoglu, B. Izgi, K. Demir
Summary: The study demonstrates that AS-OCT has a higher sensitivity in detecting KF rings compared to slit-lamp biomicroscopic examination. It can effectively detect the early stage of KF rings in patients with Wilson's Disease.
EUROPEAN REVIEW FOR MEDICAL AND PHARMACOLOGICAL SCIENCES
(2022)
Article
Ophthalmology
Jaya Dantam, David Joseph McCanna, Lakshman N. Subbaraman, Dominik Papinski, Carol Lakkis, Aftab Mirza, David A. Berntsen, Philip Morgan, Jason J. Nichols, Lyndon W. Jones
OPTOMETRY AND VISION SCIENCE
(2016)
Article
Ophthalmology
Stephanie M. Cox, David A. Berntsen, Neil Chatterjee, Sheila B. Hickson-Curran, Lyndon W. Jones, Amir M. Moezzi, Philip B. Morgan, Jason J. Nichols
OPTOMETRY AND VISION SCIENCE
(2016)
Article
Ophthalmology
David A. Berntsen, Sheila B. Hickson-Curran, Lyndon W. Jones, Jessica H. Mathew, Carole Maldonado-Codina, Philip B. Morgan, Marc M. Schulze, Jason J. Nichols
OPTOMETRY AND VISION SCIENCE
(2016)
Article
Ophthalmology
Marc-Matthias Schulze, Sruthi Srinivasan, Sheila B. Hickson-Curran, David A. Berntsen, Gillian F. Howarth, Youssef Toubouti, Philip Morgan, Jason J. Nichols, Lyndon W. Jones
OPTOMETRY AND VISION SCIENCE
(2016)
Article
Ophthalmology
Negar Babaei Omali, Miriam Heynen, Lakshman N. Subbaraman, Dominik Papinski, Carol Lakkis, Sarah L. Smith, Philip B. Morgan, David A. Berntsen, Jason J. Nichols, Lyndon W. Jones
OPTOMETRY AND VISION SCIENCE
(2016)
Article
Ophthalmology
Kelly E. Moore, Julia S. Benoit, David A. Berntsen
OPTOMETRY AND VISION SCIENCE
(2017)
Article
Ophthalmology
Mylan T. Nguyen, David A. Berntsen
OPTOMETRY AND VISION SCIENCE
(2017)
Article
Ophthalmology
Jeffrey J. Walline, Amber Gaume Giannoni, Loraine T. Sinnott, Moriah A. Chandler, Juan Huang, Donald O. Mutti, Lisa A. Jones-Jordan, David A. Berntsen
OPTOMETRY AND VISION SCIENCE
(2017)
Article
Ophthalmology
Stephanie M. Cox, David A. Berntsen, Katherine M. Bickle, Jessica H. Mathew, Daniel R. Powell, B. Kim Little, Kathrine Osborn Lorenz, Jason J. Nichols
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2018)
Article
Ophthalmology
Krystal L. Schulle, David A. Berntsen, Loraine T. Sinnott, Katherine M. Bickle, Anita T. Gostovic, Gilbert E. Pierce, Lisa A. Jones-Jordan, Donald O. Mutti, Jeffrey J. Walline
OPTOMETRY AND VISION SCIENCE
(2018)
Letter
Ophthalmology
Mark A. Bullimore, David A. Berntsen
JAMA OPHTHALMOLOGY
(2018)
Article
Ophthalmology
David A. Berntsen, Stephanie M. Cox, Katherine M. Bickle, Jessica H. Mathew, Daniel R. Powell, Scott H. Seidman, Borm Kim Little, Kathrine Osborn Lorenz, Jason J. Nichols
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2019)
Article
Ophthalmology
Donald O. Mutti, Loraine T. Sinnott, Kathleen S. Reuter, Maria K. Walker, David A. Berntsen, Lisa A. Jones-Jordan, Jeffrey J. Walline, Donald F. Everett, Kimberly J. Shaw, Juan Huang, Bradley E. Dougherty, Pamela Wessel, Jihyun Lee, Luke A. Bobay, Tina Opoku, Laura Cardenas, Krystal L. Schulle, Dashaini Retnasothie, Amber Gaume Giannoni, Anita Ticak Gostovic, Moriah A. Chandler, Mylan Nguyen, Lea Hair, Jill A. Myers, Alex D. Nixon, Katherine M. Bickle, Gilbert E. Pierce, Dustin J. Gardner, Andrew D. Pucker, Matthew Kowalski, Ann Morrison, Danielle J. Orr, Janet T. Holbrook, Jane Gwiazda, Timothy B. Edrington, John Mark Jackson, Charlotte E. Joslin
TRANSLATIONAL VISION SCIENCE & TECHNOLOGY
(2019)
Review
Ophthalmology
Augustine N. Nti, David A. Berntsen
CLINICAL AND EXPERIMENTAL OPTOMETRY
(2020)
Article
Ophthalmology
James S. Wolffsohn, Pete S. Kollbaum, David A. Berntsen, David A. Atchison, Alexandra Benavente, Arthur Bradley, Hetal Buckhurst, Michael Collins, Takashi Fujikado, Takahiro Hiraoka, Masakazu Hirota, Debbie Jones, Nicola S. Logan, Linda Lundstrom, Hidemasa Torii, Scott A. Read, Kovin Naidoo
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2019)