Review
Optics
Anton Sdobnov, Gennadii Piavchenko, Alexander Bykov, Igor Meglinski
Summary: Dynamic light scattering (DLS) is a fascinating approach allowing for real-time, non-invasive characterization of small particles undergoing Brownian motion in randomly inhomogeneous turbid scattering medium. The DLS-based techniques are widely used for blood flow and perfusion analysis in biological tissues. In this work, a review of the recent advances in DLS imaging is presented.
LASER & PHOTONICS REVIEWS
(2023)
Article
Multidisciplinary Sciences
Lionel D. Fiske, Maurice C. G. Aalders, Mitra Almasian, Ton G. van Leeuwen, Aggelos K. Katsaggelos, Oliver Cossairt, Dirk J. Faber
Summary: Optical coherence tomography (OCT) is an optical technique for volumetric visualization of translucent materials, with additional information gained through depth-resolved attenuation analysis. Despite the presence of speckle causing fluctuations in OCT images, depth-resolved attenuation analysis can still provide insight into tissue structure and organization.
SCIENTIFIC REPORTS
(2021)
Article
Optics
Xi Zhang, Zhongliang Li, Nan Nan, Xiangzhao Wang
Summary: An OCT image denoising algorithm based on sparse representation using noise estimation and global dictionary is proposed in this paper. The algorithm can efficiently remove speckle noise from OCT images and improve image quality.
Article
Optics
Jianan Fang, Kun Huang, E. Wu, Ming Yan, Heping Zeng
Summary: This article introduces an infrared 3D imaging system capable of detecting three-dimensional structure and reflectivity information. The system operates at single-photon sensitivity and femtosecond timing resolution, enabling imaging under low-light conditions. By nonlinear frequency upconversion and recording with a silicon camera, the presented system achieves high lateral and depth resolutions for 3D reconstruction. Additionally, a numerical denoiser based on spatiotemporal correlation allows the retrieval of object profile and reflectivity even with a detected flux below 0.05 photons/pixel/second. This infrared 3D imager features high detection sensitivity, precise timing resolution, and wide-field operation, offering new possibilities in life and material sciences.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Optics
Austin W. Steinforth, Jose A. Rivera, J. Gary Eden
Summary: A laser resonator architecture with an internal array of microlenses is described, allowing for continuous variation of spatial coherence and speckle contrast ratio. This architecture enables high-resolution optical imaging of dynamic objects and phenomena, with the potential for imaging through fog.
Article
Chemistry, Multidisciplinary
Amalia Coro, Ada Herrero Ruiz, Mateo Pazo-Gonzalez, Alonso Sanchez-Cruz, Tobias Busch, Alejandro Hernandez Medel, Erving C. Ximendes, Dirk H. Ortgies, Rosalia Lopez-Mendez, Ana Espinosa, Dorleta Jimenez de Aberasturi, Daniel Jaque, Nuria Fernandez Monsalve, Enrique J. de la Rosa, Catalina Hernandez-Sanchez, Emma Martin Rodriguez, Beatriz H. Juarez
Summary: In this study, the application of Ag2S nanoparticles in ocular imaging was extended by preparing them with a biocompatible amphiphilic block copolymer. This method protects the photoluminescence properties of the nanoparticles and allows for the controlled preparation of submicrometric scattering centers, enhancing colloidal stability and biocompatibility. The resulting nanoparticles exhibit improved contrast for optical coherence tomography and near-infrared imaging.
Article
Physics, Multidisciplinary
Lishuang Li, Yanan Sun, Honghui He, Gaiying He, Shuhua Ma, Weifeng Yang, Yi Wang
Summary: This study established a real-time, non-invasive system to monitor angiogenesis during wound healing, which is of great significance for evaluating new treatments for wound healing.
FRONTIERS IN PHYSICS
(2022)
Article
Multidisciplinary Sciences
Shuaibin Chang, Divya Varadarajan, Jiarui Yang, Ichun Anderson Chen, Sreekanth Kura, Caroline Magnain, Jean C. Augustinack, Bruce Fischl, Douglas N. Greve, David A. Boas, Hui Wang
Summary: This study established a generalized linear model based on Mie scattering theory that quantitatively links tissue scattering to myelin content and neuron density in the human brain. A strong linear relationship between scattering coefficient and myelin content was reported across different regions of the brain, with neuronal cell body being a secondary contribution to overall scattering. The optical property of OCT provides a label-free solution for quantifying volumetric myelin content and neuron cells in the human brain.
SCIENTIFIC REPORTS
(2022)
Article
Biochemical Research Methods
Filipp Kashirtsev, John Tressel, Jacob C. Simon, Daniel Fried
Summary: Dental fluorosis is a dental problem caused by overexposure to fluoride, the severity of which is difficult to quantitatively assess. Imaging methods in visible light and SWIR wavelengths show differences in detecting and monitoring fluorosis, with SWIR wavelengths displaying high contrast and potentially being better suited for monitoring hypomineralization on tooth surfaces.
JOURNAL OF BIOPHOTONICS
(2021)
Article
Biochemical Research Methods
Zhuo Xu, Hui Zhu, Hui Wang
Summary: In this study, speckle variation induced by intracellular motion in the urothelium was observed in OCT images, providing a dynamic contrast for segmenting urothelial cells. The distribution of intracellular motion was found to be heterogeneous, but quantifiable through decorrelation time. Utilizing intracellular motion as a dynamic contrast allowed for accurate segmentation of the urothelium, even when the urothelial layer was not visible in normal OCT images.
JOURNAL OF BIOMEDICAL OPTICS
(2021)
Review
Medicine, Research & Experimental
Arash Dadkhah, Shuliang Jiao
Summary: Photoacoustic microscopy is a hybrid optical imaging technology that provides high-resolution anatomical and functional imaging of biological tissues by imaging optical absorption contrasts with low acoustic scattering. When combined with other imaging modalities, it can reveal complementary information of tissues. Sharing the ultrasonic transducer or light source in a multimodal photoacoustic microscopy system can achieve intrinsically and precisely registered images. The recently developed penta-modal photoacoustic microscopy system features a dynamic focusing technique enabled by OCT contour scan.
EXPERIMENTAL BIOLOGY AND MEDICINE
(2021)
Review
Chemistry, Multidisciplinary
Daewoon Seong, Changho Lee, Mansik Jeon, Jeehyun Kim
Summary: In the field of otology, optical coherence tomography (OCT) has played a crucial role in non-invasively obtaining morphological structure of tissues, especially in measuring the entire region of tympanic membrane. Doppler OCT, as a functional extension of OCT, has been applied to combine motion information with structural data of tissue in otology. Over the years, Doppler OCT systems have evolved in various forms to improve the measuring sensitivity of phase difference.
APPLIED SCIENCES-BASEL
(2021)
Article
Physics, Applied
J. Hope, M. Goodwin, F. Vanholsbeeck
Summary: This study investigates changes in optical coherence tomography (OCT) images in response to evoked neural activity in the sciatic nerve of rats in vitro. The observed changes in OCT signal intensity and frequency spectra during neural activity suggest the potential for detecting osmotic swelling from ion currents in myelinated fibers using OCT. This imaging technique opens up new possibilities for functional imaging in the peripheral and central nervous systems.
JOURNAL OF PHYSICS D-APPLIED PHYSICS
(2021)
Article
Optics
Y. Chang, W. Gao
Summary: A Mueller matrix polarization parameter tomographic imaging (MMPPTI) in backscattering configuration is described for generating depth-resolved cross sectional images of biological tissue polarization parameters. Theoretical model proposed and calibration using porcine liver demonstrate the capability of the method.
OPTICS AND LASERS IN ENGINEERING
(2021)
Article
Optics
Masoud Pahlevaninezhad, Yao-Wei Huang, Majid Pahlevani, Brett Boumats, Melissa J. Suter, Federico Capasso, Hamid Pahlevaninezhad
Summary: This study demonstrates a method of achieving high-resolution optical imaging using metasurfaces, which overcome the limitations imposed by diffraction and enable imaging over a large depth range. The method was validated in optical coherence tomography and has potential for widespread applications.
Article
Biochemical Research Methods
Zhijia Yuan, Zhenguo Wang, Rubin Pan, Jingxuan Liu, Harris Cohen, Yingtian Pan
JOURNAL OF BIOMEDICAL OPTICS
(2008)
Article
Materials Science, Multidisciplinary
Maricris R. Silva, Zhijia Yuan, Jae Hun Kim, Zhenguo Wang, Melissa Hoyos, Yingtian Pan, Andrew Gouldstone
JOURNAL OF MATERIALS RESEARCH
(2009)
Article
Optics
Qi Yang, Charles A. Reisman, Zhenguo Wang, Yasufumi Fukuma, Masanori Hangai, Nagahisa Yoshimura, Atsuo Tomidokoro, Makoto Araie, Ali S. Raza, Donald C. Hood, Kinpui Chan
Article
Cell & Tissue Engineering
Zhenguo Wang, Hui Pan, Zhijia Yuan, Jingxuan Liu, Weiliam Chen, Yingtian Pan
TISSUE ENGINEERING PART C-METHODS
(2008)
Article
Biochemical Research Methods
Ying T. Pan, Zi L. Wu, Zhi J. Yuan, Zheng G. Wang, Cong W. Du
JOURNAL OF BIOMEDICAL OPTICS
(2007)
Article
Biochemical Research Methods
Zhenguo Wang, Christopher S. D. Lee, Wayne C. Waltzer, Jingxuan Liu, Huikai Xie, Zhijia Yuan, Yingtian Pan
JOURNAL OF BIOMEDICAL OPTICS
(2007)
Article
Emergency Medicine
Adam J. Singer, Zhenguo Wang, Steve A. McClain, Yingtian Pan
ACADEMIC EMERGENCY MEDICINE
(2007)
Article
Optics
Zhenguo Wang, Zhijia Yuan, Hongyu Wang, Yingtian Pan
Article
Urology & Nephrology
ZG Wang, DB Durand, M Schoenberg, YT Pan
JOURNAL OF UROLOGY
(2005)
Article
Optics
YT Pan, Q Wu, ZG Wang, PR Brink, CW Du
Article
Optics
TQ Xie, ZG Wang, YT Pan
Article
Computer Science, Software Engineering
Zhenguo Wang, Christopher S. D. Lee, Wayne C. Waltzer, Zhijia Yuan, Yingtian Pan
INTERNATIONAL JOURNAL OF IMAGE AND GRAPHICS
(2007)
Meeting Abstract
Emergency Medicine
AJ Singer, Z Wang, SA McClain, Y Pan
ANNALS OF EMERGENCY MEDICINE
(2005)
Article
Optics
TQ Xie, ZG Wang, YT Pan