期刊
OPTICS EXPRESS
卷 19, 期 17, 页码 15777-15791出版社
OPTICAL SOC AMER
DOI: 10.1364/OE.19.015777
关键词
-
类别
资金
- Program for New Century Excellent Talents in University [NCET-08-0213]
- National High Technology Research and Development Program of China [2007AA02Z303]
- National Natural Science Foundation of China [30970964, 30800339, 30801482, 30800313]
- Ph.D. Programs Foundation of Ministry of Education of China [20090142110054]
Automatic separation of arteries and veins in optical cerebral cortex images is important in clinical practice and preclinical study. In this paper, a simple but effective automatic artery-vein separation method which utilizes single-wavelength coherent illumination is presented. This method is based on the relative temporal minimum reflectance analysis of laser speckle images. The validation is demonstrated with both theoretic simulations and experimental results applied to the rat cortex. Moreover, this method can be combined with laser speckle contrast analysis so that the artery-vein separation and blood flow imaging can be simultaneously obtained using the same raw laser speckle images data to enable more accurate analysis of changes of cerebral blood flow within different tissue compartments during functional activation, disease dynamic, and neurosurgery, which may broaden the applications of laser speckle imaging in biology and medicine. (C) 2011 Optical Society of America
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据