期刊
OPTICS EXPRESS
卷 18, 期 10, 页码 10538-10550出版社
OPTICAL SOC AMER
DOI: 10.1364/OE.18.010538
关键词
-
类别
资金
- Department of Defense [W81XWH-08-1-0323, W81XWH05-1-0396]
- Pew Scholar in the Biomedical Sciences Award
In this paper, we present a method to determine, for the first time, the ratio of forward-propagating second harmonic (SHG) signal to back-propagating SHG signal (F/B) in vivo on the surface of intact tissue samples without any biopsy or tissue sectioning, using only epidetection (i.e., via a single objective lens). This method has the additional benefit of using the confocal detection apparatus already contained within common commercially available two-photon laser-scanning microscopes, and hence can allow the measurement of the SHG F/B ratio in vivo with minimal purchase of new equipment. (C) 2010 Optical Society of America
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据