Article
Multidisciplinary Sciences
Albert Van Eeckhout, Enrique Garcia-Caurel, Teresa Garnatje, Juan Carlos Escalera, Merce Durfort, Josep Vidal, Jose J. Gil, Juan Campos, Angel Lizana
Summary: Polarimetric microscopy is a mature technique in biophotonics, but is not commonly used in botany, with only specific observables like birefringence being utilized. A study on using polarimetric microscopy for plant inspection shows its potential advantages compared to standard techniques, highlighting its non-destructive nature, cost-effectiveness, and time efficiency.
SCIENTIFIC REPORTS
(2021)
Article
Materials Science, Multidisciplinary
Xiaoting Wang, Fang Zhong, Jun Kang, Can Liu, Ming Lei, Longfei Pan, Hailu Wang, Fang Wang, Ziqi Zhou, Yu Cui, Kaihui Liu, Jianlu Wang, Guozhen Shen, Chongxin Shan, Jingbo Li, Weida Hu, Zhongming Wei
Summary: The study demonstrates the utilization of a two-dimensional alpha-GeSe semiconductor to realize a polarizer-free polarization-sensitive visible/near-infrared photodetector/imager. The device exhibits impressive performances and unique polarization sensitivity. The proposed imager has the ability to sense dual-band polarization signals in the scene without polarizers, paving the way for advanced applications.
SCIENCE CHINA-MATERIALS
(2021)
Article
Astronomy & Astrophysics
Aleksei Zhuravlev, Roberto Taverna, Roberto Turolla
Summary: Investigated the impact of photon-axion mixing on the thermal spectra and polarization observables of cooling neutron stars. Found that mixing can limit the geometric configurations that reproduce the observed linear polarization fraction.
ASTROPHYSICAL JOURNAL
(2022)
Review
Chemistry, Inorganic & Nuclear
Vinayak Juvekar, Sang Jun Park, Juyoung Yoon, Hwan Myung Kim
Summary: Two-photon microscopy combined with two-photon fluorescent probes enables visualization of metal ion distribution in live tissues, facilitating the development of probes for metal ion detection. Recent progress between 2014 and 2020, including design strategies, history, and specific applications, was summarized in this review.
COORDINATION CHEMISTRY REVIEWS
(2021)
Review
Chemistry, Analytical
Hyo Won Lee, Vinayak Juvekar, Dong Joon Lee, Hwan Myung Kim
Summary: Biological events occur in specific cellular organelles to perform specialized roles in cells and collaborate with other organelles. Various methods have been used to study organelle dynamics, including two photon microscopy. This review focuses on the design strategies, photo-physical properties, and bioimaging applications of recent two-photon probes specifically localized in the endoplasmic reticulum, Golgi, lipid droplets, lysosomes, plasma membrane, and mitochondria. The summary is limited to research from 2017 onwards. © 2023 Elsevier B.V. All rights reserved.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2023)
Article
Computer Science, Artificial Intelligence
Jinyu Zhao, Yusuke Monno, Masatoshi Okutomi
Summary: This paper proposes a novel 3D reconstruction method that effectively utilizes geometric, photometric, and polarimetric cues extracted from input multi-view color-polarization images. The method estimates camera poses and an initial 3D model using standard structure-from-motion and multi-view stereo techniques, and then refines the model by optimizing photometric rendering errors and polarimetric errors. Experimental results show that the proposed method can reconstruct detailed 3D shapes without assuming specific surface materials and lighting conditions.
IEEE TRANSACTIONS ON PATTERN ANALYSIS AND MACHINE INTELLIGENCE
(2023)
Article
Optics
Colin J. R. Sheppard, Marco Castello, Giorgio Tortarolo, Alessandro Zunino, Eli Slenders, Paolo Bianchini, Giuseppe Vicidomini, Alberto Diaspro
Summary: We discuss the properties of signal strength and integrated intensity in two-photon excitation confocal microscopy and image scanning microscopy. The resolution, optical sectioning, and background rejection are all improved over nonconfocal two-photon microscopy. Replacing the pinhole of confocal two-photon microscopy with a detector array increases the peak intensity of the point spread function. The outer pixels of a detector array give signals from defocused regions, and thus the processing of these, such as through subtraction, can further improve optical sectioning and background rejection.
Article
Optics
Robert Shreiner, Kai Hao, Amy Butcher, Alexander A. High
Summary: Researchers demonstrated electrically controllable chirality by exploiting doping-dependent valley polarization of excitonic states in monolayer tungsten diselenide. They reported electrically controllable chirality in a nanophotonic interface, enabling propagation direction-dependent interactions between guided optical modes and circularly dichroic materials. This work could provide optical control over excitonic and charge-carrier behavior in integrated photonics with van der Waals heterostructures.
Article
Biochemical Research Methods
Carla Rodriguez, Albert Van Eeckhout, Laia Ferrer, Enrique Garcia-caurel, Emilio Gonzalez-arnay, Juan Campos, Angel Lizana
Summary: The potential of a predictive optical model method for tissue recognition based on statistical analysis of polarimetric indicators was highlighted. By analyzing experimental Mueller matrices of four biological tissues from 157 ex-vivo chicken samples, a logistic regression-based algorithm was developed to identify which tissue category a sample belongs to in a single dynamic measurement.
BIOMEDICAL OPTICS EXPRESS
(2021)
Article
Optics
Cam Nhung Vu, Zakarya Ouzit, Clotilde Lethiec, Michel Pellarin, Agnes Maitre, Frederic Lerouge, Laurent Coolen, Julien Laverdant
Summary: This article focuses on determining the 3D orientation of single gold nano-bipyramids (AuBPs) and deducing orientation through polarization resolved dark-field scattering. The study presents a specific experiment for selecting, analyzing, and resolving the scattering angles of individual nanoparticles. The accuracy of polarimetric measurements is evaluated through a comparison with a complete measurement of the degree of polarization (DOP) as a function of the collected numerical aperture.
OPTICS COMMUNICATIONS
(2022)
Review
Chemistry, Analytical
Vinayak Juvekar, Hyo Won Lee, Dong Joon Lee, Hwan Myung Kim
Summary: Two-photon microscopy is an important tool for deep-tissue imaging, providing high-resolution fluorescence images beyond millimeter depths. Recent research has focused on developing innovative strategies and probes for quantitative analysis using two-photon fluorescence.
TRAC-TRENDS IN ANALYTICAL CHEMISTRY
(2022)
Article
Geochemistry & Geophysics
Zejun Dong, Xuan Feng, Haoqiu Zhou, Cai Liu, Minghe Zhang, Wenjing Liang
Summary: This article investigates the polarimetric response of full-polarimetric ground-penetrating radar (FP-GPR) from anisotropic media. A mathematical relation between the measured scattering matrix affected by anisotropies and the real scattering matrix is derived, and a coefficient to characterize the polarization rotation effects is proposed. The computation results indicate that e(z)/e(x), s(z)/s(x), and antenna interval have complex effects on the polarization rotation coefficient and the H-Alpha decomposition results of three types of typical targets.
IEEE TRANSACTIONS ON GEOSCIENCE AND REMOTE SENSING
(2023)
Article
Optics
Haofeng Hu, Yilin Han, Xiaobo Li, Liubing Jiang, Li Che, Tiegen Liu, Jingsheng Zhai
Summary: This paper proposes an effective solution combining polarimetric physical model and deep neural network for suppressing scattered light and restoring target signals in underwater imaging. Experimental results demonstrate that this method improves image quality and outperforms other existing methods, even in high turbidity conditions.
Article
Optics
Kazunori Shibata
Summary: Research indicates that the quantum nature of vacuum affects electromagnetic fields, resulting in nonlinear Maxwell's equations. By extending the finite-difference time-domain (FDTD) method with quartic nonlinear electromagnetic Lagrangian, the nonlinear Maxwell's equations can be numerically solved without assumptions on the electromagnetic field. Examples of self-modulations of nonlinear electromagnetic waves in a one-dimensional cavity show that even a small nonlinear correction can accumulate to achieve significant self-modulation over a long timescale, regardless of the strength of the electromagnetic field.
Article
Astronomy & Astrophysics
Satoshi Higashino, Yuichiro Mori, Yosuke Takubo, Takeo Higuchi, Akimasa Ishikawa, Izumi Tsutsui
Summary: This study demonstrates the feasibility of utilizing weak value amplification technique in high-energy particle physics to prolong the effective lifetime of decay modes and improve the measurement precision of CP-violating parameters.
Article
Parasitology
Hend H. A. M. Abdulla, Dina Aboelsoued, Tarek K. Fang, Sobhy Abdel-Shaft, Kadria N. Abdel Megeed, Philippe Parola, Didier Raoult, Oleg Mediannikov
Summary: This study investigated equine vector-borne diseases (EVBDs) in Egypt using molecular analyses, leading to the discovery of new pathogens such as Candidatus Ehrlichia rustica and a new Ehrlichia species. The study also identified a new Theileria species Africa, along with other pathogens in donkeys and horses.
Article
Optics
Tengfei Wu, Marc Guillon, Clemence Gentner, Herve Rigneault, Gilles Tessier, Pierre Bon, Pascal Berto
Summary: In this report, a simple and effective method for superlocalizing plasmonic nanoparticles in 3D is presented, which utilizes a thin diffuser placed in the close vicinity of a camera sensor and holographic reconstruction. Experimental results demonstrate that this method enables real-time localization of 100nm gold nanoparticles with nanometer precision using a standard bright-field microscope.
Article
Computer Science, Artificial Intelligence
Stephanie Guerit, Siddharth Sivankutty, John Lee, Herve Rigneault, Laurent Jacques
Summary: Fluorescence imaging through ultrathin fibers is a promising approach to achieve high-resolution imaging at greater depths. This study proposes a novel scanning scheme called partial speckle scanning, inspired by compressive sensing theory, to perform lensless endoscopy with reduced acquisition time and without photo-bleaching. The proposed approach utilizes the subexponential random fields of speckles and the memory effect of multicore fibers to achieve higher reconstruction quality with fewer observations.
SIAM JOURNAL ON IMAGING SCIENCES
(2022)
Article
Optics
D. Septier, V Mytskaniuk, R. Habert, D. Labat, K. Baudelle, A. Cassez, G. Brevalle-Wasilewski, M. Conforti, G. Bouwmans, H. Rigneault, A. Kudlinski
Summary: We present a highly multimodal nonlinear micro-endoscope with a diameter of 2 mm, which enables label-free imaging of biological tissues. The micro-endoscope utilizes double-clad antiresonant hollow core fiber and graded-index fiber technology, allowing for various imaging modes and achieving high-resolution images.
Article
Nanoscience & Nanotechnology
Fatima El Moussawi, Matthias Hofer, Damien Labat, Andy Cassez, Geraud Bouwmans, Siddharth Sivankutty, Rosa Cossart, Olivier Vanvincq, Herve Rigneault, Esben Ravn Andresen
Summary: This study presents a novel tapered multicore fiber (MCF) component for ultraminiaturized endoscopes, addressing the power delivery issue faced by MCF-based lensless endoscopes and achieving a significant increase in two-photon signal yield.
Article
Optics
Sylvain Gigan, Ori Katz, Hilton B. de Aguiar, Esben Ravn Andresen, Alexandre Aubry, Jacopo Bertolotti, Emmanuel Bossy, Dorian Bouchet, Joshua Brake, Sophie Brasselet, Yaron Bromberg, Hui Cao, Thomas Chaigne, Zhongtao Cheng, Wonshik Choi, Tomas Cizmar, Meng Cui, Vincent R. Curtis, Hugo Defienne, Matthias Hofer, Ryoichi Horisaki, Roarke Horstmeyer, Na Ji, Aaron K. LaViolette, Jerome Mertz, Christophe Moser, Allard P. Mosk, Nicolas C. Pegard, Rafael Piestun, Sebastien Popoff, David B. Phillips, Demetri Psaltis, Babak Rahmani, Herve Rigneault, Stefan Rotter, Lei Tian, Ivo M. Vellekoop, Laura Waller, Lihong Wang, Timothy Weber, Sheng Xiao, Chris Xu, Alexey Yamilov, Changhuei Yang, Hasan Yilmaz
Summary: In the last decade, various tools such as wavefront shaping and computational methods have been developed to understand and control the propagation of light in complex mediums. This field has revolutionized the possibility of diffraction-limited imaging at depth in tissues, and a vibrant community is actively working on it.
JOURNAL OF PHYSICS-PHOTONICS
(2022)
Article
Optics
Sandro Heuke, Xavier Audier, Herve Rigneault
Summary: A double modulation scheme is proposed for stimulated Raman microscopy, where both the pump and Stokes beams are modulated at fm and 2fm. By exploiting aliasing and reduction of repetition rate, the proposed scheme amplifies the signal amplitude by a factor of 1.5, 2, and 4 for different modulation frequencies and experimental realizations at the same average power. The derived noise power for different sources shows that the double modulation scheme can achieve up to 16-fold speed improvement in stimulated Raman scattering imaging compared to single beam modulation.
Article
Chemistry, Physical
Romain Appay, Barbara Sarri, Sandro Heuke, Sebastien Boissonneau, Chang Liu, Etienne Dougy, Laurent Daniel, Didier Scavarda, Henry Dufour, Dominique Figarella-Branger, Herve Rigneault
Summary: Central nervous system tumors are a diverse group of neoplasms with different outcomes and treatment strategies. The classification of these tumors is now based on molecular parameters in addition to histopathology. Genomic characterization is crucial for identifying targeted therapies. Stimulated Raman histology (SRH) is a non-destructive imaging technique that allows for rapid examination of tissue samples without labeling or sectioning.
JOURNAL OF PHYSICAL CHEMISTRY B
(2023)
Article
Optics
Zhouping Lyu, Ksenia Abrashitova, Johannes F. de Boer, Esben R. Andresen, Herve Rigneault, Lyubov Amitonova
Summary: In this study, a flexible probe based on a multicore-multimode fiber is proposed and experimentally demonstrated for sub-diffraction imaging. The probe consists of a multicore part with 120 single-mode cores and a multimode part for structured light illumination. The results show perturbation-resilient fast sub-diffraction fiber imaging by computational compressive sensing.
Article
Optics
Jeremy Saucourt, Antonin Moreau, Julien Lumeau, Herve Rigneault, Thomas Chaigne
Summary: Optical detection of ultrasound for photoacoustic imaging using Fabry-Perot cavity sensors allows for higher spatial resolutions compared to conventional piezoelectric detection. However, precise control of the interrogation beam wavelength is required for optimal sensitivity. This study proposes the use of a broadband source and a fast-tunable acousto-optic filter to adjust the interrogation wavelength at each pixel within microseconds, overcoming fabrication constraints and improving acquisition speed.
Article
Optics
Naveen Gajendra Kumar, Siddharth Sivankutty, Victor Tsvirkun, Andy Cassez, Damien Labat, Rosa Cossart, Geraud Bouwmans, Esben Ravn Andresen, Herve Rigneault
Summary: We present a modified fiber geometry for a bending-insensitive multi-core fiber (MCF) that allows optimal light coupling in and out of the individual cores, addressing the coupling complexity and potential degradation issues of previously reported twisted MCFs. By introducing a section with straight and parallel cores at the ends of the MCF, we rectify the coupling and output light problems, enabling the development of bend-insensitive lensless endoscopes.
Article
Physics, Applied
Siddarth Shivkumar, Dekel Ranann, Samuel Metais, Sisira Suresh, Nicolas Forget, Randy Bartels, Dan Oron, Herve Rigneault
Summary: Impulsive stimulated Raman scattering (ISRS) is a promising technique for vibrational imaging below 200 cm(-1) by using a single short femtosecond pump pulse. However, ISRS lacks vibrational selectivity as all vibrational bonds within the pump-pulse bandwidth are excited. In this work, we propose two pulse-shaping strategies for selective vibrational detection by shaping the probe pulse in time.
PHYSICAL REVIEW APPLIED
(2023)
Article
Optics
Camille Scotte, Frederic Galland, Herve Rigneault
Summary: In a single-pixel camera, the object is illuminated by intensity patterns and reconstructed computationally from the total reflected or transmitted intensity measured by a single-pixel detector. We investigate whether a single-pixel camera performs better than point raster scanning in the presence of photon-noise, and find that positive intensity modulation based on Hadamard or Cosine patterns does not necessarily improve the single-to-noise ratio (SNR) of single-pixel cameras. However, the SNR is improved on object pixels at least k times brighter than the object mean signal, where k depends on the modulation scheme.
JOURNAL OF PHYSICS-PHOTONICS
(2023)
Article
Engineering, Electrical & Electronic
D. Septier, D. Labat, A. Pastre, R. Bernard, G. Brevalle-Wasilewski, H. Rigneault, G. Bouwmans, A. Kudlinski
Summary: We designed, fabricated, and characterized the first hollow core double-clad fiber coupler for nonlinear micro-endoscopy. The coupler consists of a pure silica negative curvature hollow core double-clad fiber and a highly multimode fiber fused together. The use of a low fusion temperature soft (borosilicate) glass multimode fiber enabled the fabrication of this coupler without altering the geometry of the negative curvature fiber. A power transfer of 60% from the double-clad fiber to the multimode fiber was measured at 500 nm. The applicability of the coupler was demonstrated through two-photon fluorescence and second harmonic generation imaging of unlabeled biological tissues using an endoscopic head mounted on the hollow core double-clad fiber coupler. This device greatly simplifies the integration of nonlinear micro-endoscopes based on hollow core double clad fibers.
JOURNAL OF LIGHTWAVE TECHNOLOGY
(2023)
Article
Optics
Sandro Heuke, Carla Silva Martins, Remi Andre, Loic Legoff, Herve Rigneault
Summary: Two-photon excited fluorescence (2PEF) microscopy is a popular nonlinear imaging method for biomedical samples. It uses multiple detectors and spectral filter sets to discriminate different fluorophores based on their emission behavior. However, 2PEF suffers from the loss of fluorescence photons outside the filter transmission range and may fail to discriminate fluorophores with similar emission profiles. Here, we propose an alternative 2PEF method that discriminates fluorophores based on their excitation spectra.
