Bis(acetylacetonato)copper(II) catalyzed oxidative cross-dehydrogenative coupling (CDC) for the synthesis of cc-acyloxy ethers through direct activation of α-C(sp3)-H bond of cyclic ether

A bis(acetylacetonato)copper(II)catalyzed convenient protocol has been developed for the synthesis of cc-acyloxy ethers via cross-dehydrogenative coupling (CDC) using tertiary-butylhydroperoxide (TBHP) as the oxidant. A radical mechanism is suggested for the reaction. (C) 2015 Elsevier Ltd. All rights reserved.