Article
Orthopedics
Junaid Sayani, Tobias Plotkin, Daniel Timothy Burchette, Joideep Phadnis
Summary: A systematic review of treatment studies on OCD of the capitellum from 1975 to 2020 found that nonoperative treatment was comparable to surgical treatment for low-grade lesions, while surgical treatment was superior for high-grade lesions. Factors such as capitellar physeal status, lesion location, and type of sports participation can influence treatment outcomes.
AMERICAN JOURNAL OF SPORTS MEDICINE
(2021)
Article
Radiology, Nuclear Medicine & Medical Imaging
Andrea Sprlakova-Pukova, Alena Stouracova, Martin Repko, Eva Koritakova, Jaroslav Tintera, Marek Dostal, Tomas Otasevic
Summary: The study found that there were no significant differences in the treatment effects of microfractures and scaffold implantation on cartilage defects at 6, 12, and 18 months. More substantial decrease in GAGs concentration was observed at month 6 with microfracture treatment, while the greatest decline was seen at month 12 with implantation. The decline in GAGs content and cartilage quality was also significant in the reference area and close surroundings.
ACADEMIC RADIOLOGY
(2021)
Article
Veterinary Sciences
Samuel P. Franklin, Aaron M. Stoker, Sean M. Murphy, Michael P. Kowaleski, Mitchell Gillick, Stanley E. Kim, Michael Karlin, Alan Cross, James L. Cook
Summary: This retrospective study aimed to analyze outcomes and complications associated with osteochondral allograft transplantation in dogs with chondral and osteochondral lesions. Results indicated that graft failure led to unacceptable outcomes, with a success rate of 30 out of 35 cases.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Nanoscience & Nanotechnology
Yan Lu, Yuxiang Wang, Hanjie Zhang, Zizhao Tang, Xiaolin Cui, Xing Li, Jie Liang, Qiguang Wang, Yujiang Fan, Xingdong Zhang
Summary: The study demonstrated that functionalizing collagen scaffolds with porcine decellularized extracellular matrix can promote neocartilage regeneration. Results showed that the solution form of ECM performed better in cell recruitment, proliferation, and chondrogenesis, quickly providing a favorable chondrogenic microenvironment for endogenous BMSCs.
ACS APPLIED MATERIALS & INTERFACES
(2021)
Article
Orthopedics
Matthias Pallamar, Theresa Eder, Rudolf Ganger, Sebastian Farr
Summary: This study assessed the clinical and radiographic outcomes of different surgical procedures for atraumatic osteochondrosis dissecans (OCD) of the talus in youth and adolescence. The results showed that drilling procedures had better clinical scores and a lower prevalence of joint degeneration compared to combined fixation and reconstruction procedures in stable OCD.
FOOT AND ANKLE SURGERY
(2022)
Article
Orthopedics
Anna Gussner, Danika Baskar, Matt Rohde, Ted Ganley, Kevin Shea
Summary: With the rise of social media, patients with osteochondritis dissecans (OCD) and their families are using online platforms such as Facebook, Instagram, YouTube, and TikTok to seek information and support. However, the quality of information shared in these groups is a concern. It is important to increase physician involvement and awareness of the information shared on social media platforms to improve accuracy and reliability.
JOURNAL OF PEDIATRIC ORTHOPAEDICS
(2022)
Article
Veterinary Sciences
Pearce B. Sloan, Brad White, Elizabeth M. Santschi
Summary: Osteochondrosis dissecans (OCD) is common in Thoroughbred yearlings for sale at auction, and its impact on racing outcomes is uncertain. This retrospective study investigated femoropatellar OCD in juvenile Thoroughbreds and compared the racing performance of affected horses to siblings and unaffected horses from the same sale.
EQUINE VETERINARY JOURNAL
(2023)
Article
Orthopedics
Sebastian Farr, Matthias Pallamar, Theresa Eder, Rudolf Ganger
Summary: This study achieved promising clinical outcomes in adolescent patients with advanced OCD using a novel surgical treatment combination. Radiographic results showed partial healing, indicating the need for long-term monitoring of residual changes.
ARCHIVES OF ORTHOPAEDIC AND TRAUMA SURGERY
(2021)
Article
Biology
Adrian Deichsel, Lucas Klaus Palma Kries, Michael J. Raschke, Christian Peez, Thorben Briese, Johannes Glasbrenner, Elmar Herbst, Christoph Kittl
Summary: Osteochondrosis dissecans (OCD) is a disease affecting the subchondral bone and the overlying articular cartilage, and treatment often involves refixation with implants. In this case report, a 13-year-old female patient with knee pain underwent refixation using headless magnesium compression screws after conservative treatment and subsequent displacement of the osteochondral fragment. The patient showed successful healing and pain relief at the 6-month follow-up.
Article
Orthopedics
Bryon J. X. Teo, Cheryl Gatot, Daryl Z. C. Cheng, Kevin Koo
Summary: Osteochondral defects are commonly found in Asian patients undergoing surgery for chronic lateral ankle instability, with medial lesions being prevalent and larger, while central lesions are rare. The morphology and severity of these defects may differ in Asian populations compared to what has been traditionally described.
JOURNAL OF FOOT & ANKLE SURGERY
(2021)
Article
Orthopedics
Derek T. Dee, Victor T. Hung, Connor J. Schamblin, Gregory M. Lupica, Hunter R. Hitchens, Michelle H. McGarry, Thay Q. Lee
Summary: This article introduces a novel hybrid reconstruction technique for repairing osteochondral defects of the elbow radiocapitellar joint (RC), and compares the contact characteristics before and after defect repair through biomechanical analysis. The results of the study indicate that the procedure can restore contact pressure to the intact condition while avoiding increased peak contact pressure or edge loading.
ORTHOPAEDIC JOURNAL OF SPORTS MEDICINE
(2022)
Article
Orthopedics
Mitchel R. Obey, Travis J. Hillen, J. Sam Broughton, Matthew Smith, Charles A. Goldfarb
Summary: This study describes the MRI appearance of cartilage after marrow stimulation for capitellar osteochondritis dissecans (OCD) and assesses differences between symptomatic and asymptomatic patients. The findings suggest that incomplete cartilage fill and subchondral bone edema were common, and clinical scores did not correlate with MRI cartilage findings.
JOURNAL OF HAND SURGERY-AMERICAN VOLUME
(2023)
Article
Orthopedics
Mark Ayzenberg, Benjamin Clippinger, Emily L. Slate, Scott H. Kozin, Dan A. Zlotolow
Summary: Based on the study of 15 patients who underwent osteochondral autograft transplantations for osteochondritis dissecans of the capitellum, it was found that the surgery had excellent clinical and radiographic outcomes, with good recovery and a high level of return to sports.
JOURNAL OF HAND SURGERY-AMERICAN VOLUME
(2021)
Article
Orthopedics
Tyler B. Hall, Max J. Hyman, Neeraj M. Patel
Summary: This study compared the rate of reoperation among children and adolescents undergoing osteochondral autograft (OAU) or osteochondral allograft (OAL) transfer for knee injuries. The findings showed that the overall reoperation rate was similar for OAU and OAL, but the rate was higher for open OAU procedures compared to open OAL procedures.
Article
Cell & Tissue Engineering
Frank A. Petrigliano, Nancy Q. Liu, Siyoung Lee, Jade Tassey, Arijita Sarkar, Yucheng Lin, Liangliang Li, Yifan Yu, Dawei Geng, Jiankang Zhang, Ruzanna Shkhyan, Jacob Bogdanov, Ben Van Handel, Gabriel B. Ferguson, Youngjoo Lee, Svenja Hinderer, Kuo-Chang Tseng, Aaron Kavanaugh, J. Gage Crump, April D. Pyle, Katja Schenke-Layland, Fabrizio Billi, Liming Wang, Jay Lieberman, Mark Hurtig, Denis Evseenko
Summary: Osteoarthritis affects millions worldwide, with injuries to the articular surface being a major risk factor. Current cartilage repair strategies are only moderately effective, but a newly developed stem cell-derived formulation shows potential for long-term functional repair.
NPJ REGENERATIVE MEDICINE
(2021)
