Molecular Pathogenesis of Pancreatic Cancer and Clinical Perspectives

Genome profiling of pancreatic adenocarcinoma

(2011) David J. Birnbaum et al.   GENES CHROMOSOMES & CANCER

Roles and Mechanisms of MicroRNAs in Pancreatic Cancer

(2011) Lidong Zhang et al.   WORLD JOURNAL OF SURGERY

Differential methylation of cell-free circulating DNA among patients with pancreatic cancer versus chronic pancreatitis

(2010) Thomas Liggett et al.   CANCER

Sensitive and quantitative detection of KRAS2 gene mutations in pancreatic duct juice differentiates patients with pancreatic cancer from chronic pancreatitis, potential for early detection

(2010) Chanjuan Shi et al.   CANCER BIOLOGY & THERAPY

Implication of microRNAs in drug resistance for designing novel cancer therapy

(2010) Fazlul H. Sarkar et al.   DRUG RESISTANCE UPDATES

miR-301a as an NF-κB activator in pancreatic cancer cells

(2010) Zhongxin Lu et al.   EMBO JOURNAL

LKB1 Haploinsufficiency Cooperates With Kras to Promote Pancreatic Cancer Through Suppression of p21-Dependent Growth Arrest

(2010) Jennifer P. Morton et al.   GASTROENTEROLOGY

CUX1: target of Akt signalling and mediator of resistance to apoptosis in pancreatic cancer

(2010) S. Ripka et al.   GUT

The patterns and dynamics of genomic instability in metastatic pancreatic cancer

(2010) Peter J. Campbell et al.   NATURE

Distant metastasis occurs late during the genetic evolution of pancreatic cancer

(2010) Shinichi Yachida et al.   NATURE

Acquisition of Epithelial-Mesenchymal Transition Phenotype of Gemcitabine-Resistant Pancreatic Cancer Cells Is Linked with Activation of the Notch Signaling Pathway

(2009) Z. Wang et al.   CANCER RESEARCH

Epithelial to Mesenchymal Transition Contributes to Drug Resistance in Pancreatic Cancer

(2009) T. Arumugam et al.   CANCER RESEARCH

SMAD4 Gene Mutations Are Associated with Poor Prognosis in Pancreatic Cancer

(2009) A. Blackford et al.   CLINICAL CANCER RESEARCH

PTEN regulate angiogenesis through PI3K/Akt/VEGF signaling pathway in human pancreatic cancer cells

(2009) Jiachi Ma et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Chemokine Receptor CXCR4 Enhances Proliferation in Pancreatic Cancer Cells Through AKT and ERK Dependent Pathways

(2009) Xiaoming Shen et al.   PANCREAS

Uncoupling of the LKB1-AMPKα Energy Sensor Pathway by Growth Factors and Oncogenic BRAFV600E

(2009) Rosaura Esteve-Puig et al.   PLoS One

Exomic Sequencing Identifies PALB2 as a Pancreatic Cancer Susceptibility Gene

(2009) S. Jones et al.   SCIENCE

Molecular Characterization of Pancreatic Neoplasms

(2008) Chanjuan Shi et al.   ADVANCES IN ANATOMIC PATHOLOGY

Survival of Cancer Cells Is Maintained by EGFR Independent of Its Kinase Activity

(2008) Zhang Weihua et al.   CANCER CELL

Absence of E-Cadherin Expression Distinguishes Noncohesive from Cohesive Pancreatic Cancer

(2008) J. M. Winter et al.   CLINICAL CANCER RESEARCH

Increased Risk of Cancer Other Than Melanoma in CDKN2A Founder Mutation (p16-Leiden)-Positive Melanoma Families

(2008) F. A. de Snoo et al.   CLINICAL CANCER RESEARCH

The chemokine receptor CXCR4 is expressed in pancreatic intraepithelial neoplasia

(2008) R M Thomas et al.   GUT

Intracranial Granulocytic Sarcoma After Chemotherapy for Pineal Germinoma and Testicular Cancer

(2008) Maria Grazia Passarin et al.   JOURNAL OF CLINICAL ONCOLOGY

Methylation profile of circulating plasma DNA in patients with pancreatic cancer

(2008) Anatoliy A. Melnikov et al.   JOURNAL OF SURGICAL ONCOLOGY

LNA-mediated microRNA silencing in non-human primates

(2008) Joacim Elmén et al.   NATURE

Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon

(2008) Kevin M Haigis et al.   NATURE GENETICS

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

(2008) S. Jones et al.   SCIENCE