NEDD9/Arf6-dependent endocytic trafficking of matrix metalloproteinase 14: a novel mechanism for blocking mesenchymal cell invasion and metastasis of breast cancer

NEDD9, a novel target of miR-145, increases the invasiveness of glioblastoma

(2015) Maria Carmela Speranza et al.   Oncotarget

Monitoring and Inhibiting MT1-MMP during Cancer Initiation and Progression

(2014) Sonia Pahwa et al.   Cancers

NEDD9 Depletion Destabilizes Aurora A Kinase and Heightens the Efficacy of Aurora A Inhibitors: Implications for Treatment of Metastatic Solid Tumors

(2013) R. J. Ice et al.   CANCER RESEARCH

NEDD9 promotes lung cancer metastasis through epithelial-mesenchymal transition

(2013) Yujuan Jin et al.   INTERNATIONAL JOURNAL OF CANCER

NEDD9 Depletion Leads to MMP14 Inactivation by TIMP2 and Prevents Invasion and Metastasis

(2013) Sarah L. McLaughlin et al.   MOLECULAR CANCER RESEARCH

A requirement for Nedd9 in luminal progenitor cells prior to mammary tumorigenesis in MMTV-HER2/ErbB2 mice

(2013) J L Little et al.   ONCOGENE

Impact of the Integrin Signaling Adaptor Protein NEDD9 on Prognosis and Metastatic Behavior of Human Lung Cancer

(2012) S. Kondo et al.   CLINICAL CANCER RESEARCH

N-WASP coordinates the delivery and F-actin–mediated capture of MT1-MMP at invasive pseudopods

(2012) Xinzi Yu et al.   JOURNAL OF CELL BIOLOGY

The metastasis gene NEDD9 product acts through integrin  3 and Src to promote mesenchymal motility and inhibit amoeboid motility

(2012) J. Ahn et al.   JOURNAL OF CELL SCIENCE

Classifying collective cancer cell invasion

(2012) Peter Friedl et al.   NATURE CELL BIOLOGY

NEDD9 Stabilizes Focal Adhesions, Increases Binding to the Extra-Cellular Matrix and Differentially Effects 2D versus 3D Cell Migration

(2012) Jessie Zhong et al.   PLoS One

Abl Family Kinases Modulate T Cell-Mediated Inflammation and Chemokine-Induced Migration Through the Adaptor HEF1 and the GTPase Rap1

(2012) J. J. Gu et al.   Science Signaling

GGA3 Functions as a Switch to Promote Met Receptor Recycling, Essential for Sustained ERK and Cell Migration

(2011) Christine Anna Parachoniak et al.   DEVELOPMENTAL CELL

Phosphorylation of Membrane Type 1-Matrix Metalloproteinase (MT1-MMP) and Its Vesicle-associated Membrane Protein 7 (VAMP7)-dependent Trafficking Facilitate Cell Invasion and Migration

(2011) Karla C. Williams et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Arf6 regulates AP-1B–dependent sorting in polarized epithelial cells

(2011) Elina Shteyn et al.   JOURNAL OF CELL BIOLOGY

Intravital Imaging Illuminates Transforming Growth Factor β Signaling Switches during Metastasis

(2010) Silvia Giampieri et al.   CANCER RESEARCH

Arf GAPs: Gatekeepers of vesicle generation

(2010) Anne Spang et al.   FEBS LETTERS

Matrix Metalloproteinase-Induced Epithelial-Mesenchymal Transition in Breast Cancer

(2010) Evette S. Radisky et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Regulation of invasive behavior by vascular endothelial growth factor is HEF1-dependent

(2010) J T Lucas et al.   ONCOGENE

ARF6-mediated endocytic recycling impacts cell movement, cell division and lipid homeostasis

(2010) Jill Kuglin Schweitzer et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Proteolytic and non-proteolytic roles of membrane type-1 matrix metalloproteinase in malignancy

(2009) Alex Y. Strongin   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

The EGFR-GEP100-Arf6-AMAP1 Signaling Pathway Specific to Breast Cancer Invasion and Metastasis†

(2009) Hisataka Sabe et al.   TRAFFIC

Rac Activation and Inactivation Control Plasticity of Tumor Cell Movement

(2008) Victoria Sanz-Moreno et al.   CELL

Large ARF guanine nucleotide exchange factors in membrane trafficking

(2008) N. Anders et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Epithelial mesenchymal transition traits in human breast cancer cell lines

(2008) T. Blick et al.   CLINICAL & EXPERIMENTAL METASTASIS

Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes

(2008) Juha Hakulinen et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

The EFA6 Family: Guanine Nucleotide Exchange Factors for ADP Ribosylation Factor 6 at Neuronal Synapses

(2008) Hiroyuki Sakagami   TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE