Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches
出版年份 2013 全文链接
标题
Prostate cancer progression after androgen deprivation therapy: mechanisms of castrate resistance and novel therapeutic approaches
作者
关键词
-
出版物
ONCOGENE
Volume 32, Issue 49, Pages 5501-5511
出版商
Springer Nature
发表日期
2013-06-11
DOI
10.1038/onc.2013.206
参考文献
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注意：仅列出部分参考文献，下载原文获取全部文献信息。- Serum caveolin-1, a biomarker of drug response and therapeutic target in prostate cancer models
- (2013) Salahaldin A. Tahir et al. CANCER BIOLOGY & THERAPY
- Caveolin-1-LRP6 Signaling Module Stimulates Aerobic Glycolysis in Prostate Cancer
- (2013) S. A. Tahir et al. CANCER RESEARCH
- Phase II trial of RAD001 and bicalutamide for castration-resistant prostate cancer
- (2012) Mari Nakabayashi et al. BJU INTERNATIONAL
- Inhibition of PI3K/mTOR Leads to Adaptive Resistance in Matrix-Attached Cancer Cells
- (2012) Taru Muranen et al. CANCER CELL
- Distinct Patterns of Dysregulated Expression of Enzymes Involved in Androgen Synthesis and Metabolism in Metastatic Prostate Cancer Tumors
- (2012) N. Mitsiades et al. CANCER RESEARCH
- Distinct Transcriptional Programs Mediated by the Ligand-Dependent Full-Length Androgen Receptor and Its Splice Variants in Castration-Resistant Prostate Cancer
- (2012) R. Hu et al. CANCER RESEARCH
- Androgen Receptor Splice Variants Mediate Enzalutamide Resistance in Castration-Resistant Prostate Cancer Cell Lines
- (2012) Y. Li et al. CANCER RESEARCH
- Pten Loss and RAS/MAPK Activation Cooperate to Promote EMT and Metastasis Initiated from Prostate Cancer Stem/Progenitor Cells
- (2012) D. J. Mulholland et al. CANCER RESEARCH
- AMPK Is a Negative Regulator of the Warburg Effect and Suppresses Tumor Growth In Vivo
- (2012) Brandon Faubert et al. Cell Metabolism
- Activation of -Catenin Signaling in Androgen Receptor-Negative Prostate Cancer Cells
- (2012) X. Wan et al. CLINICAL CANCER RESEARCH
- Diverse Functions of IGF/Insulin Signaling in Malignant and Noncancerous Prostate Cells: Proliferation in Cancer Cells and Differentiation in Noncancerous Cells
- (2012) Isabel Heidegger et al. ENDOCRINOLOGY
- Androgen-responsive and nonresponsive prostate cancer cells present a distinct glycolytic metabolism profile
- (2012) Cátia V. Vaz et al. INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY
- Up-regulation of hexokinaseII in myeloma cells: targeting myeloma cells with 3-bromopyruvate
- (2012) Ayako Nakano et al. JOURNAL OF BIOENERGETICS AND BIOMEMBRANES
- Cabozantinib in Patients With Advanced Prostate Cancer: Results of a Phase II Randomized Discontinuation Trial
- (2012) David C. Smith et al. JOURNAL OF CLINICAL ONCOLOGY
- Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
- (2012) Karim Fizazi et al. LANCET ONCOLOGY
- Wnt/β-catenin signalling in prostate cancer
- (2012) Robert M. Kypta et al. Nature Reviews Urology
- Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
- (2012) Howard I. Scher et al. NEW ENGLAND JOURNAL OF MEDICINE
- Abiraterone in Metastatic Prostate Cancer without Previous Chemotherapy
- (2012) Charles J. Ryan et al. NEW ENGLAND JOURNAL OF MEDICINE
- AR intragenic deletions linked to androgen receptor splice variant expression and activity in models of prostate cancer progression
- (2012) Y Li et al. ONCOGENE
- Functional Metabolic Screen Identifies 6-Phosphofructo-2-Kinase/Fructose-2,6-Biphosphatase 4 as an Important Regulator of Prostate Cancer Cell Survival
- (2012) Susana Ros et al. Cancer Discovery
- Androgen Receptor Gene Expression in Prostate Cancer Is Directly Suppressed by the Androgen Receptor Through Recruitment of Lysine-Specific Demethylase 1
- (2011) Changmeng Cai et al. CANCER CELL
- Cell Autonomous Role of PTEN in Regulating Castration-Resistant Prostate Cancer Growth
- (2011) David J. Mulholland et al. CANCER CELL
- Reciprocal Feedback Regulation of PI3K and Androgen Receptor Signaling in PTEN-Deficient Prostate Cancer
- (2011) Brett S. Carver et al. CANCER CELL
- Small Molecule Inhibitors Targeting the “Achilles' Heel” of Androgen Receptor Activity: Figure 1.
- (2011) Marianne D. Sadar CANCER RESEARCH
- Overcoming Trastuzumab Resistance in Breast Cancer by Targeting Dysregulated Glucose Metabolism
- (2011) Y. Zhao et al. CANCER RESEARCH
- Androgen Deprivation Causes Epithelial-Mesenchymal Transition in the Prostate: Implications for Androgen-Deprivation Therapy
- (2011) Y. Sun et al. CANCER RESEARCH
- The androgen receptor fuels prostate cancer by regulating central metabolism and biosynthesis
- (2011) Charles E Massie et al. EMBO JOURNAL
- Androgen receptor levels are upregulated by Akt in prostate cancer
- (2011) S. Ha et al. ENDOCRINE-RELATED CANCER
- Alternatively spliced androgen receptor variants
- (2011) Scott M Dehm et al. ENDOCRINE-RELATED CANCER
- The role of HGF/c-Met signaling in prostate cancer progression and c-Met inhibitors in clinical trials
- (2011) Andreas Varkaris et al. EXPERT OPINION ON INVESTIGATIONAL DRUGS
- Negative Androgen-Response Elements Mediate Androgen-Dependent Transcriptional Inhibition of TGF- 1 and CDK2 Promoters in the Prostate Gland
- (2011) W. Qi et al. JOURNAL OF ANDROLOGY
- Effects of Abiraterone Acetate on Androgen Signaling in Castrate-Resistant Prostate Cancer in Bone
- (2011) Eleni Efstathiou et al. JOURNAL OF CLINICAL ONCOLOGY
- The diversity of sex steroid action: novel functions of hydroxysteroid (17β) dehydrogenases as revealed by genetically modified mouse models
- (2011) Taija Saloniemi et al. JOURNAL OF ENDOCRINOLOGY
- Novel Therapies for Metastatic Castrate-Resistant Prostate Cancer
- (2011) F. Dayyani et al. JNCI-Journal of the National Cancer Institute
- Caveolin-1 Upregulation Contributes to c-Myc-Induced High-Grade Prostatic Intraepithelial Neoplasia and Prostate Cancer
- (2011) G. Yang et al. MOLECULAR CANCER RESEARCH
- SMAD4-dependent barrier constrains prostate cancer growth and metastatic progression
- (2011) Zhihu Ding et al. NATURE
- Abiraterone and Increased Survival in Metastatic Prostate Cancer
- (2011) Johann S. de Bono et al. NEW ENGLAND JOURNAL OF MEDICINE
- NANOG promotes cancer stem cell characteristics and prostate cancer resistance to androgen deprivation
- (2011) C R Jeter et al. ONCOGENE
- Advancing a clinically relevant perspective of the clonal nature of cancer
- (2011) C. Ruiz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dihydrotestosterone synthesis bypasses testosterone to drive castration-resistant prostate cancer
- (2011) K.-H. Chang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A snapshot of the expression signature of androgen receptor splicing variants and their distinctive transcriptional activities
- (2011) Rong Hu et al. PROSTATE
- Androgen stimulates glycolysis forde novolipid synthesis by increasing the activities of hexokinase 2 and 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 2 in prostate cancer cells
- (2010) Jong-Seok Moon et al. BIOCHEMICAL JOURNAL
- FGF signalling in prostate development, tissue homoeostasis and tumorigenesis
- (2010) Yongshun Lin et al. BIOSCIENCE REPORTS
- Integrative Genomic Profiling of Human Prostate Cancer
- (2010) Barry S. Taylor et al. CANCER CELL
- Distinct Genomic Alterations in Prostate Cancers in Chinese and Western Populations Suggest Alternative Pathways of Prostate Carcinogenesis
- (2010) X. Mao et al. CANCER RESEARCH
- Compensatory Upregulation of Tyrosine Kinase Etk/BMX in Response to Androgen Deprivation Promotes Castration-Resistant Growth of Prostate Cancer Cells
- (2010) B. Dai et al. CANCER RESEARCH
- The retinoblastoma tumor suppressor controls androgen signaling and human prostate cancer progression
- (2010) Ankur Sharma et al. JOURNAL OF CLINICAL INVESTIGATION
- Castration resistance in human prostate cancer is conferred by a frequently occurring androgen receptor splice variant
- (2010) Shihua Sun et al. JOURNAL OF CLINICAL INVESTIGATION
- The PI3K Pathway As Drug Target in Human Cancer
- (2010) Kevin D. Courtney et al. JOURNAL OF CLINICAL ONCOLOGY
- Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1–2 study
- (2010) Howard I Scher et al. LANCET
- Sipuleucel-T Immunotherapy for Castration-Resistant Prostate Cancer
- (2010) Philip W. Kantoff et al. NEW ENGLAND JOURNAL OF MEDICINE
- MYC Overexpression Induces Prostatic Intraepithelial Neoplasia and Loss of Nkx3.1 in Mouse Luminal Epithelial Cells
- (2010) Tsuyoshi Iwata et al. PLoS One
- Bypass Mechanisms of the Androgen Receptor Pathway in Therapy-Resistant Prostate Cancer Cell Models
- (2010) Rute B. Marques et al. PLoS One
- Integrated data from 2 randomized, double-blind, placebo-controlled, phase 3 trials of active cellular immunotherapy with sipuleucel-T in advanced prostate cancer
- (2009) Celestia S. Higano et al. CANCER
- Steroid Hormone Receptors in Prostate Cancer: A Hard Habit to Break?
- (2009) Gerhardt Attard et al. CANCER CELL
- Inhibition of Tumor Growth Progression by Antiandrogens and mTOR Inhibitor in a Pten-Deficient Mouse Model of Prostate Cancer
- (2009) W. Zhang et al. CANCER RESEARCH
- Treatment-Dependent Androgen Receptor Mutations in Prostate Cancer Exploit Multiple Mechanisms to Evade Therapy
- (2009) M. P. Steinkamp et al. CANCER RESEARCH
- Androgen Receptor Regulates a Distinct Transcription Program in Androgen-Independent Prostate Cancer
- (2009) Qianben Wang et al. CELL
- Wnt/Fz signaling and the cytoskeleton: potential roles in tumorigenesis
- (2009) Shih-Lei Lai et al. CELL RESEARCH
- Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases
- (2009) Bryan T. MacDonald et al. DEVELOPMENTAL CELL
- Targeting TGF-β in prostate cancer: therapeutic possibilities during tumor progression
- (2009) Elisabeth Jones et al. EXPERT OPINION ON THERAPEUTIC TARGETS
- Role of androgens and the androgen receptor in epithelial-mesenchymal transition and invasion of prostate cancer cells
- (2009) Meng-Lei Zhu et al. FASEB JOURNAL
- Caveolin-1 Promotes Autoregulatory, Akt-Mediated Induction of Cancer-Promoting Growth Factors in Prostate Cancer Cells
- (2009) L. Li et al. MOLECULAR CANCER RESEARCH
- The role of caveolin-1 in prostate cancer: clinical implications
- (2009) T C Thompson et al. PROSTATE CANCER AND PROSTATIC DISEASES
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Development of a Second-Generation Antiandrogen for Treatment of Advanced Prostate Cancer
- (2009) C. Tran et al. SCIENCE
- Interplay of Cadherin-Mediated Cell Adhesion and Canonical Wnt Signaling
- (2009) J. Heuberger et al. Cold Spring Harbor Perspectives in Biology
- Androgen deprivation therapy: progress in understanding mechanisms of resistance and optimizing androgen depletion
- (2009) William P Harris et al. Nature clinical practice. Urology
- Transcriptional regulation of theTGF-β1promoter by androgen receptor
- (2008) Wei Qi et al. BIOCHEMICAL JOURNAL
- Tumor Cell-Secreted Caveolin-1 Has Proangiogenic Activities in Prostate Cancer
- (2008) S. A. Tahir et al. CANCER RESEARCH
- Androgen Levels Increase by Intratumoral De novo Steroidogenesis during Progression of Castration-Resistant Prostate Cancer
- (2008) J. A. Locke et al. CANCER RESEARCH
- Maintenance of Intratumoral Androgens in Metastatic Prostate Cancer: A Mechanism for Castration-Resistant Tumor Growth
- (2008) R. B. Montgomery et al. CANCER RESEARCH
- Portrait of PTEN: Messages from mutant mice
- (2008) Akira Suzuki et al. CANCER SCIENCE
- Roles of TGFβ in metastasis
- (2008) David Padua et al. CELL RESEARCH
- Caveolin-1: A tumor-promoting role in human cancer
- (2008) Maria Shatz et al. INTERNATIONAL JOURNAL OF RADIATION BIOLOGY
- Nuclear MYC protein overexpression is an early alteration in human prostate carcinogenesis
- (2008) Bora Gurel et al. MODERN PATHOLOGY
- Regulation of androgen receptor transcriptional activity by rapamycin in prostate cancer cell proliferation and survival
- (2008) Y Wang et al. ONCOGENE
- Promoter methylation correlates with reduced Smad4 expression in advanced prostate cancer
- (2008) Alan A. Aitchison et al. PROSTATE
- Mechanisms mediating androgen receptor reactivation after castration
- (2008) Xin Yuan et al. UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS
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