Loss of microRNA-143/145 disturbs cellular growth and apoptosis of human epithelial cancers by impairing the MDM2-p53 feedback loop

Traveling Bax and Forth from Mitochondria to Control Apoptosis

(2011) Maria Eugenia Soriano et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The miR-143/145 Cluster Is a Novel Transcriptional Target of Jagged-1/Notch Signaling in Vascular Smooth Muscle Cells

(2011) Joshua M. Boucher et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

microRNA-34a expression correlates with MDM2 SNP309 polymorphism and treatment-free survival in chronic lymphocytic leukemia

(2010) D. Asslaber et al.   BLOOD

miR-145 and miR-133a function as tumour suppressors and directly regulate FSCN1 expression in bladder cancer

(2010) T Chiyomaru et al.   BRITISH JOURNAL OF CANCER

Putative tumor suppressor miR-145 inhibits colon cancer cell growth by targeting oncogene friend leukemia virus integration 1 gene

(2010) Jianjun Zhang et al.   CANCER

MicroRNA-137 promoter methylation is associated with poorer overall survival in patients with squamous cell carcinoma of the head and neck

(2010) Scott M. Langevin et al.   CANCER

MDM2 antagonist nutlin plus proteasome inhibitor velcade combination displays a synergistic anti-myeloma activity

(2010) Manujendra N. Saha et al.   CANCER BIOLOGY & THERAPY

An ARF-Independent c-MYC-Activated Tumor Suppression Pathway Mediated by Ribosomal Protein-Mdm2 Interaction

(2010) Everardo Macias et al.   CANCER CELL

Phosphorylation by Casein Kinase I Promotes the Turnover of the Mdm2 Oncoprotein via the SCFβ-TRCP Ubiquitin Ligase

(2010) Hiroyuki Inuzuka et al.   CANCER CELL

Downregulation of p53-inducible microRNAs 192, 194, and 215 Impairs the p53/MDM2 Autoregulatory Loop in Multiple Myeloma Development

(2010) Flavia Pichiorri et al.   CANCER CELL

Role of anti-oncomirs miR-143 and -145 in human colorectal tumors

(2010) Y Akao et al.   CANCER GENE THERAPY

Repression of the miR-143/145 cluster by oncogenic Ras initiates a tumor-promoting feed-forward pathway

(2010) O. A. Kent et al.   GENES & DEVELOPMENT

The Mdm2-p53 relationship evolves: Mdm2 swings both ways as an oncogene and a tumor suppressor

(2010) J. J. Manfredi   GENES & DEVELOPMENT

MicroRNA expression profiles of head and neck squamous cell carcinoma with docetaxel-induced multidrug resistance

(2010) Yuemeng Dai et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

MicroRNAs and Their Therapeutic Potential for Human Diseases: MicroRNAs, miR-143 and -145, Function as Anti-oncomirs and the Application of Chemically Modified miR-143 as an Anti-cancer Drug

(2010) Yukio Kitade et al.   JOURNAL OF PHARMACOLOGICAL SCIENCES

MiR-145, a new regulator of the DNA Fragmentation Factor-45 (DFF45)-mediated apoptotic network

(2010) Jianjun Zhang et al.   Molecular Cancer

Jmjd2c histone demethylase enhances the expression of Mdm2 oncogene

(2009) Akihiko Ishimura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MicroRNA-145 Suppresses Cell Invasion and Metastasis by Directly Targeting Mucin 1

(2009) M. Sachdeva et al.   CANCER RESEARCH

TGF-β1–induced expression of human Mdm2 correlates with late-stage metastatic breast cancer

(2009) Shinako Araki et al.   JOURNAL OF CLINICAL INVESTIGATION

Modulation of microRNA processing by p53

(2009) Hiroshi I. Suzuki et al.   NATURE

Exploiting and antagonizing microRNA regulation for therapeutic and experimental applications

(2009) Brian D. Brown et al.   NATURE REVIEWS GENETICS

Role of miR-143 targeting KRAS in colorectal tumorigenesis

(2009) X Chen et al.   ONCOGENE

p53 represses c-Myc through induction of the tumor suppressor miR-145

(2009) M. Sachdeva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mdm2 Promotes Genetic Instability and Transformation Independent of p53

(2008) A. Bouska et al.   MOLECULAR AND CELLULAR BIOLOGY