Cells of origin for cancer: an updated view from prostate cancer

Cancer statistics, 2012

(2012) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Adult Murine Prostate Basal and Luminal Cells Are Self-Sustained Lineages that Can Both Serve as Targets for Prostate Cancer Initiation

(2012) Nahyun Choi et al.   CANCER CELL

Notch and TGFβ Form a Reciprocal Positive Regulatory Loop that Suppresses Murine Prostate Basal Stem/Progenitor Cell Activity

(2012) Joseph M. Valdez et al.   Cell Stem Cell

Developmental Stage and Time Dictate the Fate of Wnt/β-Catenin-Responsive Stem Cells in the Mammary Gland

(2012) Renée van Amerongen et al.   Cell Stem Cell

Developmental stage-specific contribution of LGR5+ cells to basal and luminal epithelial lineages in the postnatal mammary gland

(2012) Karin E de Visser et al.   JOURNAL OF PATHOLOGY

Production of avian retroviruses and tissue-specific somatic retroviral gene transfer in vivo using the RCAS/TVA system

(2012) Alexander von Werder et al.   Nature Protocols

Intratumor Heterogeneity and Branched Evolution Revealed by Multiregion Sequencing

(2012) Marco Gerlinger et al.   NEW ENGLAND JOURNAL OF MEDICINE

A Single Progenitor Population Switches Behavior to Maintain and Repair Esophageal Epithelium

(2012) D. P. Doupe et al.   SCIENCE

Cell of Origin of Small Cell Lung Cancer: Inactivation of Trp53 and Rb1 in Distinct Cell Types of Adult Mouse Lung

(2011) Kate D. Sutherland et al.   CANCER CELL

Regenerated Luminal Epithelial Cells Are Derived from Preexisting Luminal Epithelial Cells in Adult Mouse Prostate

(2011) June Liu et al.   MOLECULAR ENDOCRINOLOGY

Cells of origin in cancer

(2011) Jane E. Visvader   NATURE

Distinct stem cells contribute to mammary gland development and maintenance

(2011) Alexandra Van Keymeulen et al.   NATURE

The cancer stem cell: premises, promises and challenges

(2011) Hans Clevers   NATURE MEDICINE

Identifying the cellular origin of squamous skin tumors

(2011) G. Lapouge et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A Two-Step Toward Personalized Therapies for Prostate Cancer

(2011) A. S. Goldstein et al.   Science Translational Medicine

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Differential sensitivity of epidermal cell subpopulations to β-catenin-induced ectopic hair follicle formation

(2010) Christopher M. Baker et al.   DEVELOPMENTAL BIOLOGY

Subtypes of medulloblastoma have distinct developmental origins

(2010) Paul Gibson et al.   NATURE

An oncogene–tumor suppressor cascade drives metastatic prostate cancer by coordinately activating Ras and nuclear factor-κB

(2010) Junxia Min et al.   NATURE MEDICINE

Basal epithelial stem cells are efficient targets for prostate cancer initiation

(2010) D. A. Lawson et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of a Cell of Origin for Human Prostate Cancer

(2010) A. S. Goldstein et al.   SCIENCE

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

A luminal epithelial stem cell that is a cell of origin for prostate cancer

(2009) Xi Wang et al.   NATURE

Cooperativity of TMPRSS2-ERG with PI3-kinase pathway activation in prostate oncogenesis

(2009) Jennifer C King et al.   NATURE GENETICS

Aberrant ERG expression cooperates with loss of PTEN to promote cancer progression in the prostate

(2009) Brett S Carver et al.   NATURE GENETICS

Aberrant luminal progenitors as the candidate target population for basal tumor development in BRCA1 mutation carriers

(2009) Elgene Lim et al.   NATURE MEDICINE

ETS family transcription factors collaborate with alternative signaling pathways to induce carcinoma from adult murine prostate cells

(2009) Y. Zong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Medulloblastoma Can Be Initiated by Deletion of Patched in Lineage-Restricted Progenitors or Stem Cells

(2008) Zeng-Jie Yang et al.   CANCER CELL

The miR-200 family determines the epithelial phenotype of cancer cells by targeting the E-cadherin repressors ZEB1 and ZEB2

(2008) S.-M. Park et al.   GENES & DEVELOPMENT

Generation of a prostate from a single adult stem cell

(2008) Kevin G. Leong et al.   NATURE

The miR-200 family and miR-205 regulate epithelial to mesenchymal transition by targeting ZEB1 and SIP1

(2008) Philip A. Gregory et al.   NATURE CELL BIOLOGY

A causal role for ERG in neoplastic transformation of prostate epithelium

(2008) O. Klezovitch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Trop2 identifies a subpopulation of murine and human prostate basal cells with stem cell characteristics

(2008) A. S. Goldstein et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seeding and Propagation of Untransformed Mouse Mammary Cells in the Lung

(2008) K. Podsypanina et al.   SCIENCE