CDK8 regulates E2F1 transcriptional activity through S375 phosphorylation

Dysregulation of CDK8 and Cyclin C in tumorigenesis

(2011) Wu Xu et al.   Journal of Genetics and Genomics

E2F1 suppresses Wnt/β-catenin activity through transactivation of β-catenin interacting protein ICAT

(2011) Z Wu et al.   ONCOGENE

Cdk5 Suppresses the Neuronal Cell Cycle by Disrupting the E2F1-DP1 Complex

(2010) J. Zhang et al.   JOURNAL OF NEUROSCIENCE

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

(2010) Avnish Kapoor et al.   NATURE

CDK8 is a positive regulator of transcriptional elongation within the serum response network

(2010) Aaron J Donner et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

The human Mediator complex: a versatile, genome-wide regulator of transcription

(2010) Dylan J. Taatjes   TRENDS IN BIOCHEMICAL SCIENCES

Revving the Throttle on an Oncogene: CDK8 Takes the Driver Seat

(2009) R. Firestein et al.   CANCER RESEARCH

Nuclear CDKs Drive Smad Transcriptional Activation and Turnover in BMP and TGF-β Pathways

(2009) Claudio Alarcón et al.   CELL

The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function

(2009) M. T. Knuesel et al.   GENES & DEVELOPMENT

Aurora B Kinase Regulates the Postmitotic Endoreduplication Checkpoint via Phosphorylation of the Retinoblastoma Protein at Serine 780

(2009) Jayasree S. Nair et al.   MOLECULAR BIOLOGY OF THE CELL

Ubiquitin Ligase Nedd4L Targets Activated Smad2/3 to Limit TGF-β Signaling

(2009) Sheng Gao et al.   MOLECULAR CELL

The Human CDK8 Subcomplex Is a Histone Kinase That Requires Med12 for Activity and Can Function Independently of Mediator

(2008) M. T. Knuesel et al.   MOLECULAR AND CELLULAR BIOLOGY

E2F1 represses β-catenin transcription and is antagonized by both pRB and CDK8

(2008) Erick J. Morris et al.   NATURE

CDK8 is a colorectal cancer oncogene that regulates β-catenin activity

(2008) Ron Firestein et al.   NATURE

A quantitative atlas of mitotic phosphorylation

(2008) N. Dephoure et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA