PKA phosphorylation redirects ERα to promoters of a unique gene set to induce tamoxifen resistance

microRNA-Associated Progression Pathways and Potential Therapeutic Targets Identified by Integrated mRNA and microRNA Expression Profiling in Breast Cancer

(2011) F. M. Buffa et al.   CANCER RESEARCH

A Gene Expression Signature from Human Breast Cancer Cells with Acquired Hormone Independence Identifies MYC as a Mediator of Antiestrogen Resistance

(2011) T. W. Miller et al.   CLINICAL CANCER RESEARCH

Androgen receptor driven transcription in molecular apocrine breast cancer is mediated by FoxA1

(2011) Jessica L L Robinson et al.   EMBO JOURNAL

Estrogen Induces c-mycGene Expression via an Upstream Enhancer Activated by the Estrogen Receptor and the AP-1 Transcription Factor

(2011) Chunyu Wang et al.   MOLECULAR ENDOCRINOLOGY

Aryl Hydrocarbon Receptor Modulation of Estrogen Receptor α-Mediated Gene Regulation by a Multimeric Chromatin Complex Involving the Two Receptors and the Coregulator RIP140

(2011) Zeynep Madak-Erdogan et al.   TOXICOLOGICAL SCIENCES

PKA-induced phosphorylation of ERα at serine 305 and high PAK1 levels is associated with sensitivity to tamoxifen in ER-positive breast cancer

(2010) Marleen Kok et al.   BREAST CANCER RESEARCH AND TREATMENT

Estrogen Receptor-  Phosphorylation at Serine 305, Nuclear p21-Activated Kinase 1 Expression, and Response to Tamoxifen in Postmenopausal Breast Cancer

(2010) J. Bostner et al.   CLINICAL CANCER RESEARCH

A phosphorylation code for oestrogen receptor-α predicts clinical outcome to endocrine therapy in breast cancer

(2010) Georgios P Skliris et al.   ENDOCRINE-RELATED CANCER

Growth factor stimulation induces a distinct ER  cistrome underlying breast cancer endocrine resistance

(2010) M. Lupien et al.   GENES & DEVELOPMENT

CARM1 mediates the ligand-independent and tamoxifen-resistant activation of the estrogen receptor   by cAMP

(2010) S. Carascossa et al.   GENES & DEVELOPMENT

Genomic Collaboration of Estrogen Receptor   and Extracellular Signal-Regulated Kinase 2 in Regulating Gene and Proliferation Programs

(2010) Z. Madak-Erdogan et al.   MOLECULAR AND CELLULAR BIOLOGY

Estrogen Receptor Regulates E2F1 Expression to Mediate Tamoxifen Resistance

(2010) M. C. Louie et al.   MOLECULAR CANCER RESEARCH

Prevalent positive epistasis in Escherichia coli and Saccharomyces cerevisiae metabolic networks

(2010) Xionglei He et al.   NATURE GENETICS

FOXA1 is a key determinant of estrogen receptor function and endocrine response

(2010) Antoni Hurtado et al.   NATURE GENETICS

A clustering approach for identification of enriched domains from histone modification ChIP-Seq data

(2009) Chongzhi Zang et al.   BIOINFORMATICS

ChIP-Seq of ERα and RNA polymerase II defines genes differentially responding to ligands

(2009) Willem-Jan Welboren et al.   EMBO JOURNAL

ChIP-seq: Using high-throughput sequencing to discover protein–DNA interactions

(2009) Dominic Schmidt et al.   METHODS

Coactivator Function Defines the Active Estrogen Receptor Alpha Cistrome

(2009) M. Lupien et al.   MOLECULAR AND CELLULAR BIOLOGY

An oestrogen-receptor-α-bound human chromatin interactome

(2009) Melissa J. Fullwood et al.   NATURE

Immunohistochemical validation of multiple phospho-specific epitopes for estrogen receptor α (ERα) in tissue microarrays of ERα positive human breast carcinomas

(2008) George P. Skliris et al.   BREAST CANCER RESEARCH AND TREATMENT

CARM1 Regulates Estrogen-Stimulated Breast Cancer Growth through Up-regulation of E2F1

(2008) S. Frietze et al.   CANCER RESEARCH

Tamoxifen Resistance in Breast Tumors Is Driven by Growth Factor Receptor Signaling with Repression of Classic Estrogen Receptor Genomic Function

(2008) S. Massarweh et al.   CANCER RESEARCH

Phosphorylation of the oestrogen receptor α at serine 305 and prediction of tamoxifen resistance in breast cancer

(2008) C Holm et al.   JOURNAL OF PATHOLOGY

Atypical Protein Kinase C Regulates Dual Pathways for Degradation of the Oncogenic Coactivator SRC-3/AIB1

(2008) Ping Yi et al.   MOLECULAR CELL

Unique ERα Cistromes Control Cell Type-Specific Gene Regulation

(2008) Susan A. Krum et al.   MOLECULAR ENDOCRINOLOGY

Structure of the intact PPAR-γ–RXR-α nuclear receptor complex on DNA

(2008) Vikas Chandra et al.   NATURE

Genomics of Signaling Crosstalk of Estrogen Receptor α in Breast Cancer Cells

(2008) Peter Dudek et al.   PLoS One

Identification of Functional Networks of Estrogen- and c-Myc-Responsive Genes and Their Relationship to Response to Tamoxifen Therapy in Breast Cancer

(2008) Elizabeth A. Musgrove et al.   PLoS One

Model-based Analysis of ChIP-Seq (MACS)

(2008) Yong Zhang et al.   GENOME BIOLOGY