β-Catenin signaling dosage dictates tissue-specific tumor predisposition in Apc-driven cancer

 -catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis

(2011) W. van Veelen et al.   GUT

APC mutations in colorectal tumours from FAP patients are selected for CtBP-mediated oligomerization of truncated APC

(2011) Jean Schneikert et al.   HUMAN MOLECULAR GENETICS

The C-terminus of Apc does not influence intestinal adenoma development or progression

(2011) Annabelle Lewis et al.   JOURNAL OF PATHOLOGY

Colorectal cancers show distinct mutation spectra in members of the canonical WNT signaling pathway according to their anatomical location and type of genetic instability

(2010) Cristina Albuquerque et al.   GENES CHROMOSOMES & CANCER

Oncogenic KRAS is not necessary for Wnt signalling activation in APC-associated FAP adenomas

(2010) Antònia Obrador-Hevia et al.   JOURNAL OF PATHOLOGY

Nuclear β-catenin expression and Wnt signalling: in defence of the dogma

(2010) Riccardo Fodde et al.   JOURNAL OF PATHOLOGY

Myc heterozygosity attenuates the phenotypes of APC deficiency in the small intestine

(2010) D Athineos et al.   ONCOGENE

Genetic Dissection of Differential Signaling Threshold Requirements for the Wnt/β-Catenin Pathway In Vivo

(2010) Michael Buchert et al.   PLoS Genetics

A Two-Step Model for Colon Adenoma Initiation and Progression Caused by APC Loss

(2009) Reid A. Phelps et al.   CELL

A Targeted Constitutive Mutation in the Apc Tumor Suppressor Gene Underlies Mammary But Not Intestinal Tumorigenesis

(2009) Claudia Gaspar et al.   PLoS Genetics

Distinct Thresholds Govern Myc's Biological Output In Vivo

(2008) Daniel J. Murphy et al.   CANCER CELL