Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia
出版年份 2011 全文链接
标题
Inhibiting PI3K reduces mammary tumor growth and induces hyperglycemia in a mouse model of insulin resistance and hyperinsulinemia
作者
关键词
-
出版物
ONCOGENE
Volume 31, Issue 27, Pages 3213-3222
出版商
Springer Nature
发表日期
2011-10-31
DOI
10.1038/onc.2011.495
参考文献
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注意:仅列出部分参考文献,下载原文获取全部文献信息。- PI3K inhibition results in enhanced HER signaling and acquired ERK dependency in HER2-overexpressing breast cancer
- (2011) V Serra et al. ONCOGENE
- Akt inhibitors reduce glucose uptake independently of their effects on Akt
- (2010) Shi-Xiong Tan et al. BIOCHEMICAL JOURNAL
- Medical comorbidities predict mortality in women with a history of early stage breast cancer
- (2010) Ruth E. Patterson et al. BREAST CANCER RESEARCH AND TREATMENT
- Insulin-Mediated Acceleration of Breast Cancer Development and Progression in a Nonobese Model of Type 2 Diabetes
- (2010) R. Novosyadlyy et al. CANCER RESEARCH
- Specific Roles of the p110α Isoform of Phosphatidylinsositol 3-Kinase in Hepatic Insulin Signaling and Metabolic Regulation
- (2010) Victoria Rotter Sopasakis et al. Cell Metabolism
- Mammalian target of rapamycin inhibition abrogates insulin-mediated mammary tumor progression in type 2 diabetes
- (2010) Yvonne Fierz et al. ENDOCRINE-RELATED CANCER
- Elevated Circulating IGF-I Promotes Mammary Gland Development and Proliferation
- (2010) Dara Cannata et al. ENDOCRINOLOGY
- Diabetes Mellitus and Breast Cancer Outcomes: A Systematic Review and Meta-Analysis
- (2010) Kimberly S. Peairs et al. JOURNAL OF CLINICAL ONCOLOGY
- Activated Phosphoinositide 3-Kinase/AKT Signaling Confers Resistance to Trastuzumab but not Lapatinib
- (2010) N. A. O'Brien et al. MOLECULAR CANCER THERAPEUTICS
- Activity of any class IA PI3K isoform can sustain cell proliferation and survival
- (2010) L. C. Foukas et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ligand-Independent HER2/HER3/PI3K Complex Is Disrupted by Trastuzumab and Is Effectively Inhibited by the PI3K Inhibitor GDC-0941
- (2009) Teemu T. Junttila et al. CANCER CELL
- PI3K pathway activation in breast cancer is associated with the basal-like phenotype and cancer-specific mortality
- (2009) Elena López-Knowles et al. INTERNATIONAL JOURNAL OF CANCER
- Metabolic syndrome and postmenopausal breast cancer in the ORDET cohort: A nested case–control study
- (2009) C. Agnoli et al. NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES
- NVP-BEZ235, a Dual PI3K/mTOR Inhibitor, Prevents PI3K Signaling and Inhibits the Growth of Cancer Cells with Activating PI3K Mutations
- (2008) V. Serra et al. CANCER RESEARCH
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