Prolyl isomerase Pin1 stabilizes and activates orphan nuclear receptor TR3 to promote mitogenesis

Inactivation of the Orphan Nuclear Receptor TR3/Nur77 Inhibits Pancreatic Cancer Cell and Tumor Growth

(2010) S.-O. Lee et al.   CANCER RESEARCH

A Unique Pharmacophore for Activation of the Nuclear Orphan Receptor Nur77 In vivo and In vitro

(2010) Jing-jing Liu et al.   CANCER RESEARCH

Peptidyl-Prolyl Isomerase Pin1 Markedly Enhances the Oncogenic Activity of the Rel Proteins in the Nuclear Factor- B Family

(2009) G. Fan et al.   CANCER RESEARCH

Pin1 Catalyzes Conformational Changes of Thr-187 in p27Kip1and Mediates Its Stability through a Polyubiquitination Process

(2009) Wei Zhou et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Prolyl isomerase Pin1 acts as a switch to control the degree of substrate ubiquitylation

(2009) Dirk Siepe et al.   NATURE CELL BIOLOGY

Akt phosphorylates the TR3 orphan receptor and blocks its targeting to the mitochondria

(2008) H.-Z. Chen et al.   CARCINOGENESIS

Cytosporone B is an agonist for nuclear orphan receptor Nur77

(2008) Yanyan Zhan et al.   Nature Chemical Biology

A feedback regulatory loop between methyltransferase PRMT1 and orphan receptor TR3

(2008) Na-zi Lei et al.   NUCLEIC ACIDS RESEARCH