Nuclear trafficking of the epidermal growth factor receptor family membrane proteins

Cyclooxygenase-2 Is a Novel Transcriptional Target of the Nuclear EGFR-STAT3 and EGFRvIII-STAT3 Signaling Axes

(2010) H.-W. Lo et al.   MOLECULAR CANCER RESEARCH

Management of breast cancer with targeted agents: importance of heterogenicity

(2010) Serena Di Cosimo et al.   Nature Reviews Clinical Oncology

SUMOylation Mediates the Nuclear Translocation and Signaling of the IGF-1 Receptor

(2010) B. Sehat et al.   Science Signaling

Mechanisms of Endocytosis

(2009) Gary J. Doherty et al.   Annual Review of Biochemistry

ESCRT proteins, endosome organization and mitogenic receptor down-regulation: Figure 1

(2009) Philip Woodman   BIOCHEMICAL SOCIETY TRANSACTIONS

Critical Role of ESCRT Machinery in EGFR Recycling

(2009) Aleksander Baldys et al.   BIOCHEMISTRY

Profiling the Human Protein-DNA Interactome Reveals ERK2 as a Transcriptional Repressor of Interferon Signaling

(2009) Shaohui Hu et al.   CELL

Nuclear Translocation of the Epidermal Growth Factor Receptor Family Membrane Tyrosine Kinase Receptors

(2009) S.-C. Wang et al.   CLINICAL CANCER RESEARCH

ErbB receptors and signaling pathways in cancer

(2009) Nancy E Hynes et al.   CURRENT OPINION IN CELL BIOLOGY

Ultraviolet irradiation-induces epidermal growth factor receptor (EGFR) nuclear translocation in human keratinocytes

(2009) Yiru Xu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Molecular predictors of response to trastuzumab and lapatinib in breast cancer

(2009) Francisco J. Esteva et al.   Nature Reviews Clinical Oncology

Pathways and mechanisms of endocytic recycling

(2009) Barth D. Grant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endocytosis and signalling: intertwining molecular networks

(2009) Alexander Sorkin et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Nuclear EGFR contributes to acquired resistance to cetuximab

(2009) C Li et al.   ONCOGENE

Activating and resistance mutations of EGFR in non-small-cell lung cancer: role in clinical response to EGFR tyrosine kinase inhibitors

(2009) A F Gazdar   ONCOGENE

Lapatinib, a Dual EGFR and HER2 Tyrosine Kinase Inhibitor, Downregulates Thymidylate Synthase by Inhibiting the Nuclear Translocation of EGFR and HER2

(2009) Hwang-Phill Kim et al.   PLoS One

Oncogenic EGFR Signaling Networks in Glioma

(2009) P. H. Huang et al.   Science Signaling

Inner nuclear membrane protein transport is mediated by multiple mechanisms

(2008) Nikolaj Zuleger et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The HER4/4ICD Estrogen Receptor Coactivator and BH3-Only Protein Is an Effector of Tamoxifen-Induced Apoptosis

(2008) A. Naresh et al.   CANCER RESEARCH

Membrane-anchored growth factors, the epidermal growth factor family: Beyond receptor ligands

(2008) Shigeki Higashiyama et al.   CANCER SCIENCE

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

Endocytosis and intracellular trafficking of ErbBs

(2008) Alexander Sorkin et al.   EXPERIMENTAL CELL RESEARCH

Trafficking of receptor tyrosine kinases to the nucleus

(2008) Graham Carpenter et al.   EXPERIMENTAL CELL RESEARCH

Identification of a PTEN-regulated STAT3 brain tumor suppressor pathway

(2008) N. de la Iglesia et al.   GENES & DEVELOPMENT

Membrane-anchored growth factor, HB-EGF, on the cell surface targeted to the inner nuclear membrane

(2008) Miki Hieda et al.   JOURNAL OF CELL BIOLOGY

ErbB4/HER4: Role in Mammary Gland Development, Differentiation and Growth Inhibition

(2008) Rebecca S. Muraoka-Cook et al.   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

HER4 Intracellular Domain (4ICD) Activity in the Developing Mammary Gland and Breast Cancer

(2008) Frank E. Jones   JOURNAL OF MAMMARY GLAND BIOLOGY AND NEOPLASIA

Radiation-induced caveolin-1 associated EGFR internalization is linked with nuclear EGFR transport and activation of DNA-PK

(2008) Klaus Dittmann et al.   Molecular Cancer

Nuclear expression of epidermal growth factor receptor is a novel prognostic value in patients with ovarian cancer

(2008) Weiya Xia et al.   MOLECULAR CARCINOGENESIS

EGFR Antagonists in Cancer Treatment

(2008) Fortunato Ciardiello et al.   NEW ENGLAND JOURNAL OF MEDICINE

Nuclear epidermal growth factor receptor (EGFR) interacts with signal transducer and activator of transcription 5 (STAT5) in activating Aurora-A gene expression

(2008) Liang-Yi Hung et al.   NUCLEIC ACIDS RESEARCH

EGFR Tyrosine Kinase Inhibitors in Lung Cancer: An Evolving Story

(2007) Lecia V. Sequist et al.   Annual Review of Medicine

Celecoxib Induced Tumor Cell Radiosensitization by Inhibiting Radiation Induced Nuclear EGFR Transport and DNA-Repair: A COX-2 Independent Mechanism

(2007) Klaus H. Dittmann et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Activation of protein kinase Cε stimulates DNA-repair via epidermal growth factor receptor nuclear accumulation

(2007) Gabriele Wanner et al.   RADIOTHERAPY AND ONCOLOGY