Biological reprogramming in acquired resistance to endocrine therapy of breast cancer

Targeting Fibroblast Growth Factor Receptors Blocks PI3K/AKT Signaling, Induces Apoptosis, and Impairs Mammary Tumor Outgrowth and Metastasis

(2010) J. H. Dey et al.   CANCER RESEARCH

Genetic Screen Identifies Insulin-like Growth Factor Binding Protein 5 as a Modulator of Tamoxifen Resistance in Breast Cancer

(2010) B. Y. Ahn et al.   CANCER RESEARCH

FGFR1 Amplification Drives Endocrine Therapy Resistance and Is a Therapeutic Target in Breast Cancer

(2010) N. Turner et al.   CANCER RESEARCH

Integrative molecular profiling of triple negative breast cancers identifies amplicon drivers and potential therapeutic targets

(2010) N Turner et al.   ONCOGENE

MYC regulation of a “poor-prognosis” metastatic cancer cell state

(2010) Anita Wolfer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tamoxifen Induces Expression of Immune Response-Related Genes in Cultured Normal Human Mammary Epithelial Cells

(2009) L. J. Schild-Hay et al.   CANCER RESEARCH

Estrogen receptor α geneESR1amplification may predict endocrine therapy responsiveness in breast cancer patients

(2009) Saori Tomita et al.   CANCER SCIENCE

The Role of Fibroblast Growth Factors in Tumor Growth

(2009) M. Korc et al.   CURRENT CANCER DRUG TARGETS

Transcriptional regulation of human fibroblast growth factor receptor 1 by E2F-1

(2009) Mai Kanai et al.   GENE

Endocrine resistance associated with activated ErbB system in breast cancer cells is reversed by inhibiting MAPK or PI3K/Akt signaling pathways

(2009) Sandra E. Ghayad et al.   INTERNATIONAL JOURNAL OF CANCER

Lapatinib Combined With Letrozole Versus Letrozole and Placebo As First-Line Therapy for Postmenopausal Hormone Receptor–Positive Metastatic Breast Cancer

(2009) Stephen Johnston et al.   JOURNAL OF CLINICAL ONCOLOGY

Phase II Randomized Study of Neoadjuvant Everolimus Plus Letrozole Compared With Placebo Plus Letrozole in Patients With Estrogen Receptor–Positive Breast Cancer

(2009) José Baselga et al.   JOURNAL OF CLINICAL ONCOLOGY

Use of global gene expression patterns in mechanistic studies of oestrogen action in MCF7 human breast cancer cells

(2009) A.J. Sadler et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Biological Convergence of Cancer Signatures

(2009) Xavier Solé et al.   PLoS One

Correlating measurements across samples improves accuracy of large-scale expression profile experiments

(2009) Mariano Alvarez et al.   GENOME BIOLOGY

Sparse representation and Bayesian detection of genome copy number alterations from microarray data

(2008) Roger Pique-Regi et al.   BIOINFORMATICS

Pathway analysis reveals functional convergence of gene expression profiles in breast cancer

(2008) Ronglai Shen et al.   BMC Medical Genomics

Identification of CDK10 as an Important Determinant of Resistance to Endocrine Therapy for Breast Cancer

(2008) Elizabeth Iorns et al.   CANCER CELL

Genome-Wide Analysis of Aromatase Inhibitor-Resistant, Tamoxifen-Resistant, and Long-Term Estrogen-Deprived Cells Reveals a Role for Estrogen Receptor

(2008) S. Masri et al.   CANCER RESEARCH

GATA-3 and the regulation of the mammary luminal cell fate

(2008) Hosein Kouros-Mehr et al.   CURRENT OPINION IN CELL BIOLOGY

Overexpression of CEACAM6 promotes migration and invasion of oestrogen-deprived breast cancer cells

(2008) Joan S. Lewis-Wambi et al.   EUROPEAN JOURNAL OF CANCER

Absence of ESR1 amplification in a series of breast cancers

(2008) José Adélaïde et al.   INTERNATIONAL JOURNAL OF CANCER

Double-Blind, Randomized Placebo Controlled Trial of Fulvestrant Compared With Exemestane After Prior Nonsteroidal Aromatase Inhibitor Therapy in Postmenopausal Women With Hormone Receptor–Positive, Advanced Breast Cancer: Results From EFECT

(2008) Stephen Chia et al.   JOURNAL OF CLINICAL ONCOLOGY

ESR1 gene amplification in breast cancer: a common phenomenon?

(2008) Anne Vincent-Salomon et al.   NATURE GENETICS

ESR1 gene amplification in breast cancer: a common phenomenon?

(2008) Lindsay A Brown et al.   NATURE GENETICS

ESR1 gene amplification in breast cancer: a common phenomenon?

(2008) Hugo M Horlings et al.   NATURE GENETICS

Allele-Specific Up-Regulation of FGFR2 Increases Susceptibility to Breast Cancer

(2008) Kerstin B Meyer et al.   PLOS BIOLOGY