ROS-mediated upregulation of Noxa overcomes chemoresistance in chronic lymphocytic leukemia

Standards for the Treatment of Relapsed Chronic Lymphocytic Leukemia: A Case-Based Study

(2010) Arnon P. Kater et al.   Clinical Lymphoma Myeloma & Leukemia

Role of NOXA and its ubiquitination in proteasome inhibitor-induced apoptosis in chronic lymphocytic leukemia cells

(2010) M. Baou et al.   HAEMATOLOGICA

A p38MAPK/HIF-1 Pathway Initiated by UVB Irradiation Is Required to Induce Noxa and Apoptosis of Human Keratinocytes

(2010) Kris Nys et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Caspase-8 dependent histone acetylation by a novel proteasome inhibitor, NPI-0052: a mechanism for synergy in leukemia cells

(2009) C. P. Miller et al.   BLOOD

PCI-24781 Induces Caspase and Reactive Oxygen Species-Dependent Apoptosis Through NF- B Mechanisms and Is Synergistic with Bortezomib in Lymphoma Cells

(2009) S. Bhalla et al.   CLINICAL CANCER RESEARCH

Detection of p53 dysfunction in chronic lymphocytic leukaemia cells through multiplex quantification of p53 target gene induction

(2009) R Mous et al.   LEUKEMIA

R-DHAP is effective in fludarabine-refractory chronic lymphocytic leukemia

(2009) S H Tonino et al.   LEUKEMIA

Cisplatin-mediated impairment of mitochondrial DNA metabolism inversely correlates with glutathione levels

(2008) Nuria Garrido et al.   BIOCHEMICAL JOURNAL

c-Abl kinase inhibitors overcome CD40-mediated drug resistance in CLL: implications for therapeutic targeting of chemoresistant niches

(2008) D. Y. H. Hallaert et al.   BLOOD

Mcl-1 expression has in vitro and in vivo significance in chronic lymphocytic leukemia and is associated with other poor prognostic markers

(2008) C. Pepper et al.   BLOOD

Concurrent up-regulation of BCL-XL and BCL2A1 induces approximately 1000-fold resistance to ABT-737 in chronic lymphocytic leukemia

(2008) M. Vogler et al.   BLOOD

Effective elimination of fludarabine-resistant CLL cells by PEITC through a redox-mediated mechanism

(2008) D. Trachootham et al.   BLOOD

Monoallelic TP53 inactivation is associated with poor prognosis in chronic lymphocytic leukemia: results from a detailed genetic characterization with long-term follow-up

(2008) T. Zenz et al.   BLOOD

Prognostic markers in chronic lymphocytic leukemia: A comprehensive review

(2008) Femke Van Bockstaele et al.   BLOOD REVIEWS

Valproate synergizes with purine nucleoside analogues to induce apoptosis of B-chronic lymphocytic leukaemia cells

(2008) Amel Baya Bouzar et al.   BRITISH JOURNAL OF HAEMATOLOGY

Bendamustine Is Effective in p53-Deficient B-Cell Neoplasms and Requires Oxidative Stress and Caspase-Independent Signaling

(2008) G. Roue et al.   CLINICAL CANCER RESEARCH

Phase I-II Study of Oxaliplatin, Fludarabine, Cytarabine, and Rituximab Combination Therapy in Patients With Richter's Syndrome or Fludarabine-Refractory Chronic Lymphocytic Leukemia

(2008) Apostolia M. Tsimberidou et al.   JOURNAL OF CLINICAL ONCOLOGY

Role of histone deacetylase inhibitor-induced reactive oxygen species and DNA damage in LAQ-824/fludarabine antileukemic interactions

(2008) Roberto R. Rosato et al.   MOLECULAR CANCER THERAPEUTICS