Upsides and downsides to polarity and asymmetric cell division in leukemia

Development of Notch-dependent T-cell leukemia by deregulated Rap1 signaling

(2008) S.-F. Wang et al.   BLOOD

Myelodysplastic syndromes

(2008) S. D. Nimer   BLOOD

Bone marrow trephine morphology and immunohistochemical findings in chronic myelomonocytic leukaemia

(2008) Nye-Thane Ngo et al.   BRITISH JOURNAL OF HAEMATOLOGY

In Childhood Acute Lymphoblastic Leukemia, Blasts at Different Stages of Immunophenotypic Maturation Have Stem Cell Properties

(2008) Christoph le Viseur et al.   CANCER CELL

Stem Cells and Niches: Mechanisms That Promote Stem Cell Maintenance throughout Life

(2008) Sean J. Morrison et al.   CELL

Mechanisms of Asymmetric Stem Cell Division

(2008) Juergen A. Knoblich   CELL

From endocytosis to tumors through asymmetric cell division of stem cells

(2008) Franck Coumailleau et al.   CURRENT OPINION IN CELL BIOLOGY

Divide and conquer: how asymmetric division shapes cell fate in the hematopoietic system

(2008) Kendra L Congdon et al.   CURRENT OPINION IN IMMUNOLOGY

The Tumor Suppressors Brat and Numb Regulate Transit-Amplifying Neuroblast Lineages in Drosophila

(2008) Sarah K. Bowman et al.   DEVELOPMENTAL CELL

WGEF activates Rho in the Wnt–PCP pathway and controls convergent extension in Xenopus gastrulation

(2008) Kosuke Tanegashima et al.   EMBO JOURNAL

How polarity shapes the destiny of T cells

(2008) S. Russell   JOURNAL OF CELL SCIENCE

Cell polarity and cancer - cell and tissue polarity as a non-canonical tumor suppressor

(2008) M. Lee et al.   JOURNAL OF CELL SCIENCE

A novel role for Lef-1, a central transcription mediator of Wnt signaling, in leukemogenesis

(2008) Konstantin Petropoulos et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Contributions of the Raf/MEK/ERK, PI3K/PTEN/Akt/mTOR and Jak/STAT pathways to leukemia

(2008) L S Steelman et al.   LEUKEMIA

Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation

(2008) Wei Guo et al.   NATURE

PTEN functions to 'prioritize' chemotactic cues and prevent 'distraction' in migrating neutrophils

(2008) Bryan Heit et al.   NATURE IMMUNOLOGY

Normal development is an integral part of tumorigenesis in T cell-specific PTEN-deficient mice

(2008) L. Xue et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Knockdown of synapse-associated protein Dlg1 reduces syncytium formation induced by human T-cell leukemia virus type 1

(2008) Sakiko Yoshida et al.   VIRUS GENES