PML tumor suppressor is regulated by HIPK2-mediated phosphorylation in response to DNA damage

Pondering the puzzle of PML (promyelocytic leukemia) nuclear bodies: Can we fit the pieces together using an RNA regulon?

(2008) Katherine L.B. Borden   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Acute promyelocytic leukemia: from highly fatal to highly curable

(2008) Z.-Y. Wang et al.   BLOOD

Peters Plus Syndrome Is a New Congenital Disorder of Glycosylation and Involves DefectiveO-Glycosylation of Thrombospondin Type 1 Repeats

(2008) Daniel Hess et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PML targeting eradicates quiescent leukaemia-initiating cells

(2008) Keisuke Ito et al.   NATURE

RNF4 is a poly-SUMO-specific E3 ubiquitin ligase required for arsenic-induced PML degradation

(2008) Michael H. Tatham et al.   NATURE CELL BIOLOGY

Arsenic degrades PML or PML–RARα through a SUMO-triggered RNF4/ubiquitin-mediated pathway

(2008) Valérie Lallemand-Breitenbach et al.   NATURE CELL BIOLOGY

Mechanism for ubiquitylation of the leukemia fusion proteins AML1-ETO and PML-RARα

(2007) Oliver H. Krämer et al.   FASEB JOURNAL