期刊
OCULAR SURFACE
卷 10, 期 1, 页码 2-14出版社
ELSEVIER
DOI: 10.1016/j.jtos.2012.01.002
关键词
allodynia; corneal pain; dry eye; hyperalgesia; inflammation; nociceptive network; pain
资金
- Boston Foundation for Sight
The traditional model of dry eye disease based on tear deficiency has presented us with many unanswered questions. Recent studies support the notion that dry eyelike symptoms represent non-specific corneal pain and provide new insights into the mechanisms that sustain the integrity of the optical tear layer. Thus, this enigmatic disease can be viewed with a new perspective, which involves the dysfunctional corneal pain system as a central pathogenetic feature of a series of disorders collectively known today as dry eye.
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