Article
Medicine, General & Internal
Michal Dembski, Anna Nowinska, Klaudia Ulfik-Dembska, Edward Wylegala
Summary: This study used SS-OCT to determine the mean reference values of anterior segment parameters in healthy Caucasian individuals, finding significant differences between sexes. Parameters of the cornea were found to differ significantly between males and females, with the iridocorneal angle being smallest in the upper quadrant.
JOURNAL OF CLINICAL MEDICINE
(2021)
Article
Engineering, Biomedical
Yoel Garcia Marin, Marta Skrok, Damian Siedlecki, Stephen J. Vincent, Michael J. Collins, David Alonso-Caneiro
Summary: This study presents an algorithm based on graph-search theory and boundary-specific image transformation for segmenting anterior segment OCT images, demonstrating reliable extraction of clinically relevant parameters with high agreement with manual segmentation.
BIOCYBERNETICS AND BIOMEDICAL ENGINEERING
(2021)
Article
Optics
Oscar Ramos-Soto, Hang Chan Jo, Robert J. Zawadzki, Dae Yu Kim, Sandra E. Balderas-Mata
Summary: In this study, an automated method for iris and corneal segmentation and measurement of morphometric parameters in zebrafish eyes is proposed. The method combines image processing techniques and deep learning algorithms to achieve automatic segmentation and measurement. The effectiveness of the method is evaluated by comparing the results with manual measurements, which show high reliability. This automated framework can be used for large-scale studies on zebrafish anterior chamber morphology.
Article
Medicine, General & Internal
Yoshiaki Takahashi, Takao Hirano, Marie Nakamura, Yoshiaki Chiku, Ken Hoshiyama, Satoko Akahane, Keita Akahane, Toshinori Murata
Summary: This study found that the use of SF6 gas during anterior chamber surgery may lead to decreased ACD and IOL position, especially in cases with a 6 mm diameter IOL, warning of potential complications. However, at 1 month postoperatively, there were no significant differences in ACD, IOL position, and RPE among different groups, regardless of IOL diameter or SF6 gas injection.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Michal Dembski, Anna Nowinska, Klaudia Ulfik-Dembska, Edward Wylegala
Summary: This study used SS-OCT to investigate the characteristics of the iridocorneal angle and cornea in patients with PEX syndrome. The results showed that PEX syndrome significantly affected the anterior eye segment, including higher keratometric values, shallower anterior chamber depth, thicker iris, and narrower angle parameters. These characteristic features of PEX syndrome can be detected using SS-OCT, which can assist clinicians in managing the disease properly.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Biochemical Research Methods
Steve Frisken, Trevor Anderson, Armin Segref, Dirk Lorenser, Grant Frisken
Summary: HP-OCT is a parallel spectral domain imaging technology that is well-suited for imaging the anterior segment of the eye. This study demonstrates that sparsely sampled volumes can be registered without active eye tracking to produce motion artifact-free 3D volumes. The anterior volume provides comprehensive 3D biometric information, including lens position, curvature, epithelial thickness, tilt, and axial length. Moreover, by changing a detachable lens, high-resolution anterior volumes and posterior volume images for preoperative assessment of the posterior segment can be captured. Importantly, the retinal volumes have the same Nyquist range as the anterior imaging mode.
BIOMEDICAL OPTICS EXPRESS
(2023)
Article
Ophthalmology
Basak Bostanci Ceran, Serdar Ozates, Hasan Basri Arifoglu, Emrullah Tasindi
Summary: Contact lens users who wear the lenses overnight show increased vessel density in the superficial layers of the perilimbal region, suggesting new vessel formation in the conjunctiva. Anterior segment OCTA may be useful for evaluating initial changes in limbal vasculature in contact lens users.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2021)
Article
Ophthalmology
Cristina Cagliari, Paulo Schor, Luiz Formentin, Cesar Lipener, Myrna Serapiao dos Santos, Helena Oliveira, Jose Ney de Carvalho Raulino Junior, Denise de Freitas
Summary: This study aimed to investigate the corneal alterations in patients with keratoconus who wore scleral contact lenses (ScCLs), with a specific focus on corneal endothelial assessment. The results showed that there were no adverse effects on the cornea or endothelium over a 90-day period of wearing ScCLs, and there was no evidence of disease progression.
EYE & CONTACT LENS-SCIENCE AND CLINICAL PRACTICE
(2022)
Article
Optics
Jianan Fang, Kun Huang, E. Wu, Ming Yan, Heping Zeng
Summary: This article introduces an infrared 3D imaging system capable of detecting three-dimensional structure and reflectivity information. The system operates at single-photon sensitivity and femtosecond timing resolution, enabling imaging under low-light conditions. By nonlinear frequency upconversion and recording with a silicon camera, the presented system achieves high lateral and depth resolutions for 3D reconstruction. Additionally, a numerical denoiser based on spatiotemporal correlation allows the retrieval of object profile and reflectivity even with a detected flux below 0.05 photons/pixel/second. This infrared 3D imager features high detection sensitivity, precise timing resolution, and wide-field operation, offering new possibilities in life and material sciences.
LIGHT-SCIENCE & APPLICATIONS
(2023)
Article
Medicine, General & Internal
Naoya Yoshihara, Hiroto Terasaki, Hideki Shiihara, Ryoh Funatsu, Takehiro Yamashita, Taiji Sakamoto
Summary: This study aimed to objectively and quantitatively evaluate the degree of particle density in the anterior chamber after laser iridotomy (LI) using anterior segment optical coherence tomography (AS-OCT). The researchers successfully quantified the accumulation of anterior chamber particles by analyzing AS-OCT images. They found that this simple and repeatable technique can non-invasively and objectively evaluate particles in the anterior chamber, including inflammatory cells.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Oncology
Marina Concilio, Gilda Cennamo, Mariapaola Giordano, Federica Fossataro, Luca D'Andrea, Nicola Ciampa, Roberta Naddei, Francesca Orlando, Fausto Tranfa, Maria Alessio
Summary: Blau syndrome is a rare granulomatous auto-inflammatory disease characterized by joint, skin, and ocular involvement. Anterior Segment-Optical Coherence Tomography (AS-OCT) is a valuable tool for improving the diagnosis of ocular involvement in pediatric patients with BS.
PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY
(2021)
Article
Ophthalmology
Yingying Dai, Shaodan Zhang, Meixiao Shen, Zi Jin, Yuheng Zhou, Shuling Ye, Chenhong Bao, Dexi Zhu
Summary: The study demonstrates that the AS-OCT-based PAS model can be useful in identifying the presence of synechial angle closure and evaluating the extent of PAS in a single eye.
GRAEFES ARCHIVE FOR CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
(2021)
Article
Optics
Robbie Murray, Ashley Lyons
Summary: Optical Coherence Tomography (OCT) is a 3D imaging technology that provides micron scale depth resolution, surpassing the millimetre scale typically achieved in Light Detection and Ranging (LiDAR). However, the lack of coherence in LiDAR scenes limits the feasibility of OCT. This paper presents a quantum interference inspired LiDAR approach that achieves OCT depth resolutions without requiring high levels of stability. The enhanced resolution opens doors for LiDAR in various applications.
Article
Ophthalmology
Daniel Ruminski, J. Sebag, Raul Duarte Toledo, Alfonso Jimenez-Villar, Jan K. Nowak, Silvestre Manzanera, Pablo Artal, Ireneusz Grulkowski
Summary: This study characterized age-related changes in anterior human vitreous using 3-D swept source optical coherence tomography and found that opacification is associated with increased light scattering and CSF degradation. SS-OCT enables high-resolution optical evaluation of vitreous opacities.
INVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE
(2021)
Review
Ophthalmology
Jeewan S. Titiyal, Manpreet Kaur, Sridevi Nair, Namrata Sharma
Summary: Intraoperative optical coherence tomography (iOCT) provides real-time visualization of ocular structures during surgery, aiding in decision-making and guidance for various anterior segment surgeries. Its efficacy and feasibility have been well established, particularly in lamellar keratoplasty and endothelial keratoplasty. iOCT also has applications in phacoemulsification, glaucoma surgeries, and pediatric patients, while ongoing technological advances aim to improve limitations related to instrument compatibility and real-time image analysis.
SURVEY OF OPHTHALMOLOGY
(2021)
