Article
Environmental Sciences
Jian Cheng, Hong Su, Zhiwei Xu, Shilu Tong
Summary: The study found that cold had a more acute effect on the risk of AMI for men, women, and the elderly, while heat had a longer delayed effect on the risk of AMI for men and adults. Individuals who had never experienced AMI and the elderly with diabetes or hyperlipidaemia were particularly vulnerable to cold, while men who had never had AMI or had hypertension or hyperlipidaemia, as well as women who had previously suffered AMI, were particularly susceptible to heat. The effects of temperature on the risk of AMI at sub-daily timescales should be taken into consideration to prevent cardiac events.
ENVIRONMENTAL RESEARCH
(2021)
Review
Medicine, General & Internal
Breda Hennessey, Nestor Sabatovicz Jr, Maria Del Trigo
Summary: Acute ischaemic mitral regurgitation (IMR) is a rare and challenging complication following acute myocardial infarction. Despite advancements in surgical and percutaneous interventions, prognosis for patients with acute IMR is often poor. This review focuses on diagnosis, echocardiographic features, and current treatment options for patients with acute IMR.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Medicine, General & Internal
Salman Al Jerdi, Naveed Akhtar, Ziyad Mahfoud, Saadat Kamran, Ashfaq Shuaib
Summary: The study aims to compare the long-term outcomes of acute ischemic stroke patients in the Middle-Eastern population. The results indicate that previous cerebrovascular/cardiovascular diseases significantly increase the risk of major cardiovascular events and early mortality.
Article
Cardiac & Cardiovascular Systems
Corina Grey, Rod Jackson, Sue Wells, Billy Wu, Mar Pujades-Rodriguez, Morten Schmidt, Vanessa Selak, Andrew J. Kerr
Summary: This study examines the trends in ischaemic heart disease (IHD) incidence and prevalence in New Zealand from 2005 to 2016. The results show that both the incidence and prevalence of IHD have declined in men and women of all age groups. Despite population growth, the total number of people living with IHD has decreased, particularly in the older age groups.
EUROPEAN JOURNAL OF PREVENTIVE CARDIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Bharathi Upadhya, James J. Willard, Laura C. Lovato, Michael V. Rocco, Cora E. Lewis, Suzanne Oparil, William C. Cushman, Jeffrey T. Bates, Natalie A. Bello, Gerard Aurigemma, Karen C. Johnson, Carlos J. Rodriguez, Dominic S. Raj, Anjay Rastogi, Leonardo Tamariz, Alan Wiggers, Dalane W. Kitzman
Summary: In the SPRINT study, intensive blood pressure treatment reduced acute decompensated HFpEF and HFrEF events. After initial incident ADHF, subsequent hospital admission and mortality rates were high and similar for patients who developed HFpEF or HFrEF. Randomization to the intensive arm did not change the risks for subsequent all-cause or HF events in either HFpEF or HFrEF, with age and Black race being independent predictors of clinical outcomes for those who developed HFpEF.
CIRCULATION-HEART FAILURE
(2021)
Article
Cardiac & Cardiovascular Systems
Jeppe Kofoed Petersen, Jawad Haider Butt, Adelina Yafasova, Christian Torp-Pedersen, Rikke Sorensen, Christina Kruuse, Naja Emborg Vinding, Anna Gundlund, Lars Kober, Emil Loldrup Fosbol, Lauge Ostergaard
Summary: This study aimed to examine the 1-year prognosis of patients surviving acute coronary syndrome (ACS) with concomitant first-time detected atrial fibrillation (AF). The results showed that first-time detected AF in ACS patients was strongly associated with ischaemic stroke, mortality, and bleeding rates comparable to patients with a history of AF.
EUROPEAN HEART JOURNAL
(2021)
Article
Cardiac & Cardiovascular Systems
Amil. M. M. Shah, Brian Claggett, Narayana Prasad, Guichu Li, Mayra Volquez, Karola Jering, Maja Cikes, Attila Kovacs, Wilfried Mullens, Jose C. Nicolau, Lars Kober, Peter Van der Meer, Pardeep. S. S. Jhund, Ghionul Ibram, Martin Lefkowitz, Yinong Zhou, Scott. D. D. Solomon, Marc A. Pfeffer
Summary: This study compared the effects of sacubitril/valsartan and ramipril on left ventricular function and adverse remodeling after acute myocardial infarction (AMI). The results showed that patients randomized to sacubitril/valsartan had better improvements in filling pressure, left ventricular volume changes, and other aspects compared to those randomized to ramipril.
Article
Cardiac & Cardiovascular Systems
Judit Cubedo, Teresa Padro, Gemma Vilahur, Filippo Crea, Robert F. Storey, Jose Luis Lopez Sendon, Juan Carlos Kaski, Alessandro Sionis, Jordi Sans-Rosello, Estefania Fernandez-Peregrina, Alex Gallinat, Lina Badimon
Summary: This study found that circulating levels of glycosylated apolipoprotein J decrease significantly in the early phase of acute myocardial infarction, and lower levels are associated with increased rates of recurrent ischemic events and mortality in AMI patients after 6 months.
EUROPEAN HEART JOURNAL
(2022)
Article
Cardiac & Cardiovascular Systems
Judit Cubedo, Teresa Padro, Gemma Vilahur, Filippo Crea, Robert F. Storey, Jose Luis Lopez Sendon, Juan Carlos Kaski, Alessandro Sionis, Jordi Sans-Rosello, Estefania Fernandez-Peregrina, Alex Gallinat, Lina Badimon
Summary: The study found that myocardial ischemia leads to intracellular accumulation of non-glycosylated ApoJ and a reduction in ApoJ-Glyc secretion. Circulating levels of glycosylated apolipoprotein J significantly decrease early in AMI patients, serving as an indicator of ischemic events. Lower levels of ApoJ-Glyc at admission in ST-elevation myocardial infarction patients are associated with a higher rate of recurrent ischemic events and mortality.
EUROPEAN HEART JOURNAL
(2022)
Article
Medical Laboratory Technology
Bing Zhao, Yilan Li, Xueyan Lang, Shaohong Fang, Zhaoying Li, Lulu Li, Lei Xing, Yao Zhang
Summary: This study found a relationship between metabolic acid load and post-myocardial infarction heart failure (post-MI HF). The results showed that patients with higher levels of serum albumin corrected anion gap (ACAG) had a higher risk of both out-of-hospital and in-hospital HF. Changes in renal function and high-sensitivity C-reactive protein levels partially mediated this association between metabolic acid load and HF incidence.
CLINICA CHIMICA ACTA
(2023)
Article
Medicine, General & Internal
Jihoon Kim, Danbee Kang, Sung Eun Kim, Hyejeong Park, Taek Kyu Park, Joo Myung Lee, Jeong Hoon Yang, Young Bin Song, Jin-Ho Choi, Seung-Hyuk Choi, Hyeon-Cheol Gwon, Eliseo Guallar, Juhee Cho, Joo-Yong Hahn
Summary: In this study, the treatment effects of fimasartan in heart failure patients were compared to other angiotensin II receptor blockers (ARBs). It was found that fimasartan had comparable treatment effects for a composite of all-cause death, recurrent MI, hospitalization for heart failure, and stroke in patients with heart failure after MI.
JOURNAL OF KOREAN MEDICAL SCIENCE
(2023)
Article
Biochemistry & Molecular Biology
Qinghai Zhang, Xin He, Jing Ling, Qizhong Xiang, Minqi Li, Huiqi Zhao, Qinghua Fu, Yi Tang, Jin He, Wenjuan Fan, Yan Zhang, Hongwei Pan, Jianqiang Peng, Zhaofen Zheng
Summary: A pilot prospective cohort study was conducted to assess the association between plasma cell-free DNA (cfDNA) levels and the risk of heart failure (HF) in acute myocardial infarction (AMI) patients. The study found that AMI patients with higher cfDNA levels at admission showed higher levels of certain biomarkers, and cfDNA was positively correlated with cardiac troponin I and soluble suppression of tumorigenicity 2. Multivariate Cox analysis showed that higher cfDNA levels were an effective risk predictor for HF incidence after AMI. This study suggests that cfDNA levels at admission are associated with the incidence of HF in AMI patients.
DNA AND CELL BIOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
J. Ranjit Arnold, Andrew P. Vanezis, Glenn C. Rodrigo, Florence Y. Lai, Prathap Kanagala, Sheraz Nazir, Jamal N. Khan, Leong Ng, Kamal Chitkara, J. Gerry Coghlan, Simon Hetherington, Nilesh J. Samani, Gerald P. McCann
Summary: Remote ischaemic conditioning (CRIC) following primary percutaneous coronary intervention (P-PCI) can improve longitudinal strain in infarct-related segments and attenuate the increase in circumferential strain in remote segments.
BASIC RESEARCH IN CARDIOLOGY
(2022)
Article
Engineering, Environmental
Yixuan Jiang, Renjie Chen, Wenhui Peng, Yun Luo, Xiaomin Chen, Qianfeng Jiang, Bingjiang Han, Guohai Su, Yusen Duan, Juntao Huo, Xinkai Qu, Qingyan Fu, Haidong Kan
Summary: This study conducted a case-crossover study among 20,867 acute myocardial infarction (AMI) patients from 46 hospitals in Shanghai, China. The results showed that ultrafine particles (UFPs) below 0.10 μm were significantly associated with the onset of AMI, with a linear exposure-response relationship. The associations occurred immediately after exposure, lasted for approximately 6 hours, and attenuated thereafter.
ENVIRONMENTAL SCIENCE & TECHNOLOGY
(2023)
Article
Cardiac & Cardiovascular Systems
Ming Dong, Dishen Chen, Yanxia Zhu, Shu Yang, Santosh Kumar, Rui Zhang, Yin Zhou, Ziyi Yang, Na Zheng, Ting Zhu, Jiaqing Xiang, Yun Liu, Lin Kang, Jie Liu
Summary: This study found that aging increases the size of myocardial infarction and impairs cardiac contractile function. The expression of MLCK3 and the activity of MLC2 do not increase in the aging hearts after myocardial infarction. miR-146a-5p down-regulates MMP2/16 expression, which in turn increases MLCK3 expression and MLC2 activity. However, this regulatory mechanism is compromised in senescent cardiomyocytes or in hearts lacking miR-146a.
CARDIOVASCULAR RESEARCH
(2023)
Article
Public, Environmental & Occupational Health
Filip Norlen, Per Gustavsson, Pernilla Wiebert, Lars Rylander, Magnus Westgren, Nils Plato, Maria Albin, Jenny Selander
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2019)
Article
Public, Environmental & Occupational Health
Ayman Alhamdow, Yona J. Essig, Annette M. Krais, Per Gustavsson, Hakan Tinnerberg, Christian H. Lindh, Jessika Hagberg, Pal Graff, Maria Albin, Karin Broberg
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2020)
Article
Public, Environmental & Occupational Health
Helena Skroder, Hans Pettersson, Maria Albin, Per Gustavsson, Lars Rylander, Filip Norlen, Jenny Selander
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2020)
Article
Environmental Sciences
Karin Grahn, Per Gustavsson, Tomas Andersson, Anders Linden, Tomas Hemmingsson, Jenny Selander, Pernilla Wiebert
Summary: Occupational exposure to particles, such as respirable crystalline silica, gypsum and insulation material, diesel exhaust, and various organic particles, increases the risk of developing COPD, especially in men. There is a positive exposure-response relationship for certain particles like RCS, gypsum and insulation, diesel exhaust, and welding fumes in relation to COPD risk. Reduction of these exposures in the work environment is crucial for preventing future cases of COPD, and further studies are needed to investigate exposure-response relationships in more detail.
ENVIRONMENTAL RESEARCH
(2021)
Article
Public, Environmental & Occupational Health
Sara Corbin, Kayo Togawa, Joachim Schuz, Charlotte Le Cornet, Beatrice Fervers, Maria Feychting, Pernilla Wiebert, Johnni Hansen, Susanne Oksbjerg Dalton, Kristina Kjaerheim, Karl-Christian Nordby, Ragnhild Strand Ostrem, Niels E. Skakkebaek, Sanni Uuksulainen, Eero Pukkala, Ann Olsson
Summary: The large-scale NORD-TEST analysis found no evidence of an association between parental prenatal exposures in wood-related jobs and testicular germ cell tumors (TGCT) in sons. While paternal wood-related job was associated with a decreased risk of TGCT in offspring, specific wood-related jobs like upholsterers, sawyers, or construction carpenters were not significantly associated with the risk of TGCT.
INTERNATIONAL ARCHIVES OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH
(2022)
Article
Oncology
Ann Olsson, Neela Guha, Liacine Bouaoun, Hans Kromhout, Susan Peters, Jack Siemiatycki, Vikki Ho, Per Gustavsson, Paolo Boffetta, Roel Vermeulen, Thomas Behrens, Thomas Bruening, Benjamin Kendzia, Pascal Guenel, Daniele Luce, Stefan Karrasch, Heinz-Erich Wichmann, Dario Consonni, Maria Teresa Landi, Neil E. Caporaso, Franco Merletti, Dario Mirabelli, Lorenzo Richiardi, Karl-Heinz Joeckel, Wolfgang Ahrens, Hermann Pohlabeln, Adonina Tardon, David Zaridze, John K. Field, Jolanta Lissowska, Beata Swiatkowska, John R. McLaughlin, Paul A. Demers, Vladimir Bencko, Lenka Foretova, Vladimir Janout, Tamas Pandics, Eleonora Fabianova, Dana Mates, Francesco Forastiere, Bas Bueno-de-Mesquita, Joachim Schuez, Kurt Straif
Summary: This study investigated the association between occupational exposure to PAH and lung cancer risk. The results showed an elevated risk of lung cancer among both men and women with PAH exposure. The study also found joint effects between PAH and smoking. However, more recent studies did not show an increased risk of lung cancer associated with PAH.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2022)
Article
Environmental Sciences
Theo Bodin, Nuria Matilla-Santander, Jenny Selander, Per Gustavsson, Tomas Hemmingsson, Gun Johansson, Johanna Jonsson, Katarina Kjellberg, Bertina Kreshpaj, Cecilia Orellana, Eskil Wadensjo, Maria Albin
Summary: This study identified a continuous increase in precarious employment in the Swedish workforce over the past 25 years, especially more pronounced in specific groups, posing a challenge to the existing trade union bargaining system.
INTERNATIONAL JOURNAL OF ENVIRONMENTAL RESEARCH AND PUBLIC HEALTH
(2022)
Article
Public, Environmental & Occupational Health
Pernilla Wiebert, Tomas Andersson, Maria Feychting, Bengt Sjogren, Nils Plato, Per Gustavsson
Summary: This study aimed to assess the risk of acute myocardial infarction (AMI) after long-term exposure to respirable crystalline silica (RCS) and to explore differences in risk between men and women. The results showed that women exposed to RCS had a higher risk of AMI, while men had a relatively lower risk. In the highest quartile of cumulative exposure, the risk of AMI was higher for women. In conclusion, occupational exposure to RCS increases the risk of AMI, with women being more sensitive to RCS than men.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Review
Clinical Neurology
I. Larsson, K. Aili, M. Lonn, P. Svedberg, J. M. Nygren, A. Ivarsson, P. Johansson
Summary: This review aims to summarize the evidence on the effectiveness of sleep interventions for improving sleep, quality of life, and ADHD symptoms in children with ADHD. The study found that a few behavioral and pharmacological interventions have some effect on improving sleep quality and reducing ADHD symptoms, but the certainty of the evidence is low.
Article
Public, Environmental & Occupational Health
Per Gustavsson, Carolina Bigert, Tomas Andersson, Manzur Kader, Mikko Harma, Jenny Selander, Theo Bodin, Maria Albin
Summary: This study examined the association between night work and breast cancer risk. The results showed that working night shifts for 8 or more years was associated with an increased risk of postmenopausal breast cancer, although the follow-up period was short and information on night work before 2008 was lacking.
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Rehabilitation
Maria Loenn, Katarina Aili, Petra Svedberg, Jens Nygren, Hakan Jarbin, Ingrid Larsson
Summary: In this study, the use of weighted blankets for children with ADHD and sleeping difficulties was explored. The findings revealed that using weighted blankets can help regulate emotions, improve sleep quality, and promote daily activities and sleep balance. Therefore, promoting the use of weighted blankets can assist in the management of daily life for children with ADHD.
OCCUPATIONAL THERAPY INTERNATIONAL
(2023)
Letter
Public, Environmental & Occupational Health
Per Gustavsson, Carolina Bigert, Tomas Andersson, Manzur Kader, Mikko Haermae, Jenny Selander, Theo Bodin, Maria Albin
OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
(2023)
Article
Rehabilitation
[Anonymous]
AUSTRALIAN OCCUPATIONAL THERAPY JOURNAL
(2021)
Article
Rheumatology
Anna Ilar, Per Gustavsson, Pernilla Wiebert, Lars Alfredsson