Article
Medicine, General & Internal
Anjali Gupta, Quan Chen, Lauren E. Wilson, Bin Huang, Maria Pisu, Margaret Liang, Rebecca A. Previs, Haley A. Moss, Kevin C. Ward, Maria J. Schymura, Andrew Berchuck, Tomi F. Akinyemiju
Summary: This study indicates that poor health care access is associated with racial and ethnic disparities in ovarian cancer survival. The research found that healthcare affordability and availability were significantly associated with consulting a gynecologic oncologist and receiving surgery. However, these factors did not fully explain the disparities between racial and ethnic groups.
Article
Otorhinolaryngology
Amanda Del Risco, Alex Cherches, Sherri L. Smith, Kristal M. Riska
Summary: This study retrospectively reviewed the charts of 458 patients diagnosed with benign paroxysmal positional vertigo (BPPV) in primary care. It found gaps in adherence to the 2017 AAO-HNS guidelines for the management and treatment of BPPV. However, these gaps did not differ by sex, race, or insurance status.
OTOLARYNGOLOGY-HEAD AND NECK SURGERY
(2023)
Article
Oncology
Fa Chen, Christina E. Bailey, Ronald D. Alvarez, Xiao-Ou Shu, Wei Zheng
Summary: Non-adherence to NCCN treatment guidelines is the most significant factor contributing to racial disparities in ovarian cancer survival between black and white patients, followed by access to care and comorbidity. These factors combined explain 59.1% of racial survival disparities.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Obstetrics & Gynecology
Anna Jo Bodurtha Smith, Jeremy Applebaum, Amanda Nickles Fader
Summary: This study found that the Medicaid expansion under the ACA was associated with improved 1-year survival among ovarian cancer patients, which was primarily mediated by earlier diagnosis. However, there were differences in the impact of the expansion based on race and geographic location.
OBSTETRICS AND GYNECOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Mario Luca Morieri, Enrico Longato, Barbara Di Camillo, Giovanni Sparacino, Angelo Avogaro, Gian Paolo Fadini
Summary: This observational study found that managing patients with T2D according to international standards for pharmacological management based on a treat-to-benefit approach was associated with a lower risk of major adverse cardiovascular events, heart failure, and mortality. These results provide ex-post validation of the ADA/EASD treatment algorithm.
CARDIOVASCULAR DIABETOLOGY
(2022)
Article
Oncology
Rachel Campbell, Daniel S. J. Costa, Martin R. Stockler, Yeh Chen Lee, Jonathan A. Ledermann, Dominique Berton, Jalid Sehouli, Felicia T. Roncolato, Rachel O. Connell, Aikou Okamoto, Jane Bryce, Amit M. Oza, Elisabeth Avall-Lundqvist, Jonathan S. Berek, Anne Lanceley, Florence Joly, Felix Hilpert, Amanda Feeney, Marie C. Kaminsky, Katrina Diamante, Michael L. Friedlander, Madeleine T. King
Summary: The purpose of this study was to examine the symptom benefit and adverse effects of palliative chemotherapy in women with recurrent ovarian cancer using the MOST tool. The study identified four symptom clusters and found associations between psychological symptoms, disease/treatment-related symptoms, and poorer health-related quality of life.
GYNECOLOGIC ONCOLOGY
(2022)
Article
Surgery
Robert J. Beaulieu, Jeremy Albright, Erin Jeruzal, M. Ashraf Mansour, Abdulhameed Aziz, Nicolas J. Mouawad, Nicholas H. Osborne, Peter K. Henke
Summary: The study found that a statewide hospital collaborative with incentivized semiannual meetings led to significant improvements in hospital adherence to best practice guidelines, including preoperative skin preparation, intraoperative antibiotic redosing, statin use at discharge, and reducing transfusions. Teaching hospital and urban or rural status did not affect adherence rates.
JOURNAL OF VASCULAR SURGERY
(2022)
Article
Pediatrics
Julianne E. Burns, Cary Thurm, James W. Antoon, Carlos G. Grijalva, Matt Hall, Adam L. Hersh, Gabrielle Z. Hester, Emilie Korn, Mario A. Reyes, Samir S. Shah, Balagangadhar R. Totapally, Ronald J. Teufel
Summary: During the COVID-19 pandemic, treatment guidelines for children with coronavirus disease 2019 (COVID-19) have evolved rapidly. The December 2020 guideline from the Infectious Diseases Society of America (IDSA) recommended the use of steroids for critical disease and suggested steroids and remdesivir for severe disease. This study evaluated the changes in medication use for children hospitalized with COVID-19 after the publication of the guideline. The findings showed a decline in the uptake and incomplete adherence to guideline-directed therapies for children with severe and critical disease.
Article
Medicine, General & Internal
Steven J. Atlas, Anna N. A. Tosteson, Timothy E. Burdick, Adam Wright, Erica S. Breslau, Tin H. Dang, Amy J. Wint, Rebecca E. Smith, Kimberly A. Harris, Li Zhou, Jennifer S. Haas
Summary: In this survey study of primary care practitioners, deficiencies in systems for managing abnormal cancer screening test results were reported, highlighting the need for comprehensive organ-agnostic systems to promote timely follow-up.
Article
Oncology
Tomi Akinyemiju, Quan Chen, Lauren E. Wilson, Rebecca A. Previs, Ashwini Joshi, Margaret Liang, Maria Pisu, Kevin C. Ward, Andrew Berchuck, Maria J. Schymura, Bin Huang
Summary: Ovarian cancer survival disparities have persisted due to lack of access to quality treatment. Structural equation modeling was used to evaluate the associations between race and ovarian cancer treatment mediated through healthcare access domains.
CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
(2023)
Article
Oncology
N. M. S. Baldewpersad Tewarie, W. J. van Driel, M. van Ham, M. W. Wouters, R. Kruitwagen
Summary: The Dutch Gynecological Oncology Audit (DGOA) was established in 2014 to audit gynecological malignancies in the Netherlands. The first results from clinical auditing for ovarian cancer show trends in treatment initiation and surgical procedures over time. Data from the audit highlights variations in quality of care between hospitals and aims to improve nationwide care quality by sharing best practices.
Article
Oncology
Haley A. Moss, Ling Chen, Dawn L. Hershman, Brittany Davidson, Jason D. Wright
Summary: This study evaluated medical adherence for ovarian cancer patients receiving PARP inhibitor therapy and found that a quarter of patients may be sub-optimally adherent. Factors such as age, comorbidities, insurance plan, and year of PARP inhibitor initiation were not significantly associated with non-adherence. Further research should focus on identifying at-risk patients and interventions to improve adherence.
GYNECOLOGIC ONCOLOGY
(2021)
Article
Oncology
Jessica Liu McMullin, Jyotirmay Sharma, Theresa Gillespie, Snehal G. Patel, Collin J. Weber, Neil D. Saunders
Summary: There is a high degree of non-adherence to treatment guidelines for medullary thyroid cancer patients. Treatment adherent to guidelines is associated with improved overall survival.
ANNALS OF SURGICAL ONCOLOGY
(2023)
Review
Multidisciplinary Sciences
Angela Kabulo Mwape, Kelly Ann Schmidtke, Celia Brown
Summary: There is a lack of instruments available to assess the knowledge and attitudes of healthcare professionals towards antibiotic use and UTI treatment. The existing instruments have not undergone the full development process to ensure that all psychometric properties are met. Thus, their ability to provide a robust measurement of knowledge and attitudes is doubtful. A need exists for an instrument that can fully and accurately measure the constructs of knowledge and attitude of healthcare professionals in the treatment of UTIs.
Review
Oncology
Jacek Jan Sznurkowski
Summary: This review aims to establish guidelines for ovarian cancer maintenance therapy based on scientific evidence. Based on the available evidence, bevacizumab should be preserved for second line maintenance therapy, and maintenance therapy with PARP inhibitors should be offered to all advanced ovarian cancer patients who have responded to first line platinum-based chemotherapy.
