Article
Nutrition & Dietetics
Alicja Kolodziejczyk-Nowotarska, Renata Bokiniec, Joanna Seliga-Siwecka
Summary: A study was conducted to assess the effectiveness of monitored vitamin D supplementation in preterm infants. Results showed that a higher percentage of infants in the monitored group had safe vitamin D levels, while potential vitamin D toxicity was observed in the standard treatment group. Therefore, vitamin D intake should be between 800-1000 IU and monitored to avoid overdose.
Article
Surgery
Pichit Sittitrai, Donyarat Ruenmarkkaew, Hanpon Klibngern, Tapanut Ariyanon, Nutthiya Hanprasertpong, Somkamon Boonyaprapa, Maysayawan Sreesawat
Summary: This study evaluated the efficacy of perioperative and postoperative calcium and vitamin D supplementation in reducing symptomatic hypocalcemia. The results showed that perioperative supplementation significantly decreased the occurrence of symptomatic hypocalcemia and shortened the recovery period, while there were no significant differences in other indicators between the two groups.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Infectious Diseases
Keren Middelkoop, Justine Stewart, Neil Walker, Carmen Delport, David A. Jolliffe, Anna K. Coussens, James Nuttall, Jonathan C. Y. Tang, William D. Fraser, Christopher J. Griffiths, Geeta Trilok Kumar, Suzanne Filteau, Richard L. Hooper, Robert J. Wilkinson, Linda-Gail Bekker, Adrian R. Martineau
Summary: This study aimed to determine whether weekly oral supplementation with 10,000 IU vitamin D3 for 3 years reduces the risk of sensitization to M. tuberculosis in South African schoolchildren aged 6-11 years with negative QFT-Plus assay results. A randomized placebo-controlled trial was conducted in Cape Town, including 1682 children. The results showed that weekly vitamin D3 supplementation for 3 years increased serum 25(OH)D concentrations among QFT-Plus-negative Cape Town schoolchildren but did not reduce their risk of QFTPlus conversion.
INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES
(2023)
Article
Cell Biology
Magali Marti, Johanne E. Spreckels, Purnika Damindi Ranasinghe, Erik Wejryd, Giovanna Marchini, Eva Sverremark-Ekstrom, Maria C. Jenmalm, Thomas Abrahamsson
Summary: Probiotics may exert benefits in modulating the gut microbiota composition during the first month in extremely low birth weight infants, leading to increased bacterial diversity and abundance of Lactobacillus reuteri, while reducing the abundance of certain harmful bacterial families.
CELL REPORTS MEDICINE
(2021)
Article
Nutrition & Dietetics
Jan K. Nowak, Paulina Sobkowiak, Slawomira Drzymala-Czyz, Patrycja Krzyzanowska-Jankowska, Ewa Sapiejka, Wojciech Skorupa, Andrzej Pogorzelski, Agata Nowicka, Irena Wojsyk-Banaszak, Szymon Kurek, Barbara Zielinska-Psuja, Aleksandra Lisowska, Jaroslaw Walkowiak
Summary: The study showed that liposomes could improve the bioavailability of vitamin A, while cyclodextrins could enhance the bioavailability of vitamins D3 and E. This may be beneficial for pancreatic-insufficient CF patients, but further research is needed.
Article
Orthopedics
Matthew T. Weintraub, Jonathan Guntin, JaeWon Yang, Anne DeBenedetti, Vasili Karas, Craig J. Della Valle, Denis Nam
Summary: This randomized controlled trial aimed to investigate the effects of a one-time dose of vitamin D3 prior to total knee arthroplasty. The results showed no significant improvements in functional scores, walking test times, or complications in the early postoperative period when compared to the placebo group.
JOURNAL OF ARTHROPLASTY
(2023)
Article
Nutrition & Dietetics
Wirun Thongchumnum, Sakda Arj-Ong Vallibhakara, Areepan Sophonsritsuk, Orawin Vallibhakara
Summary: This study aimed to evaluate the potential of vitamin E as an alternative treatment for chronic insomnia. The results showed that vitamin E significantly improved sleep quality and reduced the use of sedative drugs.
Article
Obstetrics & Gynecology
Rupsa C. Boelig, Corina N. Schoen, Heather Frey, Alexis C. Gimovsky, Edward Springel, Sami Backley, Vincenzo Berghella
Summary: This study aimed to compare vaginal progesterone with 17-hydroxyprogesterone caproate in preventing recurrent preterm birth in singleton pregnancies with previous spontaneous preterm birth. The results showed that vaginal progesterone did not reduce the risk of recurrent preterm birth by 50% compared to 17-OHPC, but it may lead to increased latency to delivery.
AMERICAN JOURNAL OF OBSTETRICS AND GYNECOLOGY
(2022)
Article
Urology & Nephrology
Luigi Morrone, Suetonia C. Palmer, Valeria M. Saglimbene, Annalisa Perna, Giuseppe Cianciolo, Domenico Russo, Loreto Gesualdo, Patrizia Natale, Antonio Santoro, Sandro Mazzaferro, Mario Cozzolino, Adamasco Cupisti, Marina Di Luca, Biagio Di Iorio, Giovanni F. M. Strippoli
Summary: This study found that calcifediol supplementation for patients undergoing hemodialysis with vitamin D insufficiency did not have definitive effects on reducing mortality and cardiovascular outcomes.
JOURNAL OF NEPHROLOGY
(2022)
Article
Nutrition & Dietetics
Josipa Domazet Bugarin, Svjetlana Dosenovic, Darko Ilic, Nikola Delic, Ivana Saric, Ivo Ugrina, Sanda Stojanovic Stipic, Bozidar Duplancic, Lenko Saric
Summary: COVID-19 symptoms range from asymptomatic cases to severe illness requiring hospitalization and intensive care. Low vitamin D levels have been associated with increased severity and mortality of COVID-19. However, this study found no significant benefit of vitamin D supplementation in patients with severe COVID-19 disease admitted to the ICU and in need of respiratory support.
Article
Nutrition & Dietetics
Yakun Liu, Cailin Ding, Ruone Xu, Kai Wang, Dan Zhang, Wenbo Pang, Wenjun Tu, Yajun Chen
Summary: Vitamin D supplementation during pregnancy is associated with improved offspring vitamin D sufficiency status, improved fetal linear growth, and reduced fetal or neonatal mortality. However, no significant effects were found on birth weight, risk of low birth weight, and risk of preterm birth.
CLINICAL NUTRITION
(2022)
Article
Multidisciplinary Sciences
Eman Said, Shrook Mousa, May Fawzi, Nirmeen A. Sabry, Samar Farid
Summary: The study compared the effects of high-dose vitamin A plus E and high-dose vitamin A plus E with zinc on patients with T2DM. Results showed that the group receiving high-dose vitamin A plus E with zinc had significant improvements in blood glucose control, beta-cell function, and insulin secretion.
JOURNAL OF ADVANCED RESEARCH
(2021)
Article
Immunology
Ya-Ning Huang, Hsin Chi, Nan -Chang Chiu, Ching-Ying Huang, Sung-Tse Li, Jin-Yuan Wang, Daniel Tsung-Ning Huang
Summary: The study found that vitamin D supplementation may have a small preventative effect against influenza infection in preschool children, but does not affect enterovirus infection. High-dose short-term vitamin D intervention might be a way to elevate children's serum vitamin D levels.
JOURNAL OF MICROBIOLOGY IMMUNOLOGY AND INFECTION
(2022)
Article
Nutrition & Dietetics
Harriet Johansson, Giuseppe Spadola, Giulio Tosti, Mario Mandala, Alessandro M. Minisini, Paola Queirolo, Valentina Aristarco, Federica Baldini, Emilia Cocorocchio, Elena Albertazzi, Leonardo Zichichi, Saverio Cinieri, Costantino Jemos, Giovanni Mazzarol, Patrizia Gnagnarella, Debora Macis, Ines Tedeschi, Emanuela Omodeo Sale, Luigia Stefania Stucci, Bernardo Bonanni, Alessandro Testori, Elisabetta Pennacchioli, Pier Francesco Ferrucci, Sara Gandini
Summary: In a study involving newly resected stage II melanoma patients, adjuvant vitamin D3 significantly increased serum 25OHD levels, particularly in patients with a baseline Breslow score under 3 mm. Patients with low 25OHD levels and Breslow score >= 3 mm had shorter disease-free survival, suggesting a potential impact of vitamin D on melanoma prognosis. Larger trials with vitamin D supplementation in melanoma subjects are needed to further investigate these findings.
Article
Clinical Neurology
Hong Kuang Tan, Kaavya Narasimhalu, Simon Kang Seng Ting, Shahul Hameed, Hui Meng Chang, Deidre Anne De Silva, Christopher Li Hsian Chen, Eng King Tan
Summary: This study aimed to examine the effect of B-vitamin supplementation on post-stroke cognitive decline, depressive symptoms, and anxiety symptoms. The results showed no benefit of B-vitamin supplementation for these sequelae, while depressive symptoms were associated with larger anterior cerebral infarcts.
INTERNATIONAL JOURNAL OF STROKE
(2023)
Article
Obstetrics & Gynecology
Maged M. Costantine, Madeline Murguia Rice, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, Alan T. N. Tita, John M. Thorp, Edward K. Chien, Alan M. Peaceman, Sean C. Blackwell
Summary: This study aims to evaluate whether the values and shape of the glucose curve during an oral glucose tolerance test (OGTT) in pregnancy can identify women at risk of developing hypertension later in life. The results suggest that the 2-hour OGTT value was positively associated with the primary outcome, while the 3-hour OGTT value was negatively associated. Furthermore, a monophasic OGTT response was associated with an increased risk of hypertension.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Anna Palatnik, Lisa Mele, Brian M. Casey, Michael W. Varner, Yoram Sorokin, Uma M. Reddy, Ronald J. Wapner, John M. Thorp, George R. Saade, Alan T. N. Tita, Dwight J. Rouse, Baha Sibai, Maged M. Costantine, Brian M. Mercer, Jorge E. Tolosa, Steve N. Caritis
Summary: This study examined the association between hypertensive disorders of pregnancy (HDP) and neurodevelopmental outcomes in offspring. The results showed that HDP diagnosis was associated with language delay at 2 years of age, but not with other long-term neurodevelopmental outcomes.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Ashley N. Battarbee, Melissa S. Stockwell, Michael Varner, Gabriella Newes-Adeyi, Michael Daugherty, Cynthia Gyamfi-Bannerman, Alan T. Tita, Kelly Vorwaller, Celibell Vargas, Akila Subramaniam, Lawrence Reichle, Romeo R. Galang, Emily Powers, Miriam Lucca-Susana, Mickey Parks, Tiffany J. Chen, Hilda Razzaghi, Fatimah S. Dawood
Summary: Most pregnant women are worried about COVID-19 illness, but less than 50% are willing to get vaccinated during pregnancy. Non-Hispanic Black and Hispanic women have lower odds of accepting a vaccine, highlighting the need to prioritize strategies to address perceived barriers among groups at high risk for COVID-19.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Michelle P. Debbink, Torri D. Metz, Richard E. Nelson, Sophie E. Janes, Alexandra Kroes, Lori J. Begaye, Cara C. Heuser, Marcela C. Smid, Robert M. Silver, Michael W. Varner, Brett D. Einerson
Summary: A retrospective cohort study was conducted on delivery admissions, revealing that admissions complicated by severe maternal morbidity (SMM) incurred 2.5 to 4 times higher costs compared to uncomplicated deliveries. The cost differences varied depending on the criteria used to define SMM.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Anna Palatnik, Paula McGee, Jennifer L. Bailit, Ronald J. Wapner, Michael W. Varner, John M. Thorp, Steve N. Caritis, Mona Prasad, Alan T. N. Tita, George R. Saade, Dwight J. Rouse, Sean C. Blackwell
Summary: This study found that Black and Hispanic HDP patients had higher rates of severe maternal morbidity, but the racial disparities disappeared after controlling for other factors.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Kara M. Rood, Lynda G. Ugwu, William A. Grobman, Jennifer L. Bailit, Ronald J. Wapner, Michael W. Varner, John M. Thorp, Steve N. Caritis, Alan T. N. Tita, George R. Saade, Dwight J. Rouse, Sean C. Blackwell, Jorge E. Tolosa
Summary: This study examines the factors associated with suboptimal receipt of antenatal corticosteroids (ANCS) among individuals who deliver between 24 and 34 weeks of gestation. The results show that there are significant variations in the administration and timing of ANCS among different hospitals, indicating opportunities for improvement.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Mara J. Dinsmoor, Lynda G. Ugwu, Jennifer L. Bailit, Uma M. Reddy, Ronald J. Wapner, Michael W. Varner, John M. Thorp, Steve N. Caritis, Mona Prasad, Alan T. N. Tita, George R. Saade, Yoram Sorokin, Dwight J. Rouse, Sean C. Blackwell, Jorge E. Tolosa
Summary: Super morbid obesity is significantly associated with increased serious maternal morbidity and mortality; however, cesarean appears to mediate this association. Obesity and morbid obesity are not associated with maternal morbidity and mortality.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Daniel N. Pasko, Paula McGee, William A. Grobman, Jennifer L. Bailit, Uma M. Reddy, Ronald J. Wapner, Michael W. Varner, John M. Thorp, Steve N. Caritis, Mona Prasad, George R. Saade, Yoram Sorokin, Dwight J. Rouse, Jorge E. Tolosa
Summary: This study used the TGCS system to analyze cesarean delivery frequencies and identified term singletons in vertex presentation with a prior cesarean delivery as the primary contributors. It also found variations in cesarean delivery frequencies among hospitals and the influence of patient characteristics on these variations.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Erin M. Cleary, Douglas A. Kniss, Lida M. Fette, Brenna L. Hughes, George R. Saade, Mara J. Dinsmoor, Uma M. Reddy, Cynthia Gyamfi-Bannerman, Michael W. Varner, William H. Goodnight, Alan T. N. Tita, Geeta K. Swamy, Kent D. Heyborne, Edward K. Chien, Suneet P. Chauhan, Yasser Y. El-Sayed, Brian M. Casey, Samuel Parry, Hyagriv N. Simhan, Peter G. Napolitano
Summary: In a cohort of parturients with primary CMV infection, nicotine exposure was not associated with offspring hearing dysfunction assessed with DPOAEs.
AMERICAN JOURNAL OF PERINATOLOGY
(2022)
Article
Obstetrics & Gynecology
Ashley N. Battarbee, Lisa Mele, Mark B. Landon, Michael W. Varner, Brian M. Casey, Uma M. Reddy, Ronald J. Wapner, Dwight J. Rouse, John M. Thorp, Edward K. Chien, George Saade, Beth A. Plunkett, Sean C. Blackwell
Summary: The objective of this study was to evaluate the association between mild gestational diabetes mellitus (GDM) and obesity with metabolic and cardiovascular markers 5 to 10 years after pregnancy. The results showed that prior GDM and obesity were associated with increased insulin resistance but no consistent cardiovascular dysfunction or alterations in insulin secretion.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Review
Peripheral Vascular Disease
Karen C. Schliep, Hailey Mclean, Bin Yan, Fares Qeadan, Lauren H. Theilen, Adam de Havenon, Jennifer J. Majersik, Truls Ostbye, Surendra Sharma, Michael W. Varner
Summary: Previous meta-analyses have shown that women with a history of hypertensive disorders of pregnancy (HDP) have a 2- to 4-fold increased risk of later cardiovascular disease. This study aims to summarize the evidence for the impact of HDP on dementia and explore the unique associations between HDP and dementia subtypes.
Article
Obstetrics & Gynecology
Ashley Battarbee, Lisa B. Mele, Mark W. Landon, Michael M. Varner, Brian M. Casey, Uma J. Reddy, Ronald J. Wapner, Dwight M. Rouse, John K. Thorp, Edward Chien, George M. Saade, Alan C. Peaceman, Sean Blackwell
Summary: This study aimed to measure the association between hypertensive disorders of pregnancy (HDP) and long-term maternal metabolic and cardiovascular biomarkers. The results showed no association between HDP and metabolic or cardiovascular biomarkers, but patients with preeclampsia may have lower levels of oxidative stress/cardiac ischemia.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Maged M. M. Costantine, Alan T. N. Tita, Lisa Mele, Brian M. M. Casey, Alan M. M. Peaceman, Michael W. W. Varner, Uma M. M. Reddy, Ronald J. J. Wapner, John M. M. Thorp, George R. R. Saade, Dwight J. J. Rouse, Baha Sibai, Brian M. M. Mercer, Steve N. N. Caritis
Summary: The study aimed to assess the association between being small for gestational age (SGA), large for gestational age (LGA), or having a small or large head circumference (HC) at birth and adverse neurodevelopmental outcomes. The results showed that SGA at birth was associated with a decrease in child IQ and higher odds of child IQ < 85 at 5 years of age, while LGA at birth was not associated with adverse outcomes. Using a fetal growth standard did not improve the detection of newborns at risk of adverse neurodevelopment.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Michael W. Varner, Elizabeth A. Thom, C. Michael Cotten, Susan R. Hintz, Grier P. Page, Dwight J. Rouse, Brian M. Mercer, Maged M. Costantine, Yoram Sorokin, John M. Thorp Jr, Susan M. Ramin, Marshall W. Carpenter, Mary J. O'Sullivan, Alan M. Peaceman, George R. Saade, Donald J. Dudley, Steve N. Caritis
Summary: This study found genetic variants associated with adverse neurodevelopmental outcomes in extremely low birth weight infants, including a variant in the SERPINE1 gene that is associated with cerebral palsy or death.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)
Article
Obstetrics & Gynecology
Ann M. Bruno, Amanda A. Allshouse, Ashley E. Benson, Christian Con Yost, Torri D. Metz, Michael W. Varner, Robert M. Silver, D. Ware Branch
Summary: Thrombotic markers in pregnant individuals are not affected by SARS-CoV-2 infection, but a high rate of LAC positivity is common. The severity of the disease is not associated with D-dimer levels and LAC positivity.
AMERICAN JOURNAL OF PERINATOLOGY
(2023)