Review
Surgery
Mohammad Kermansaravi, Amir Hossein Davarpanah Jazi, Shahab Shahabi Shahmiri, Foolad Eghbali, Rohollah Valizadeh, Masoud Rezvani
Summary: Morbid obesity is a global chronic disease, and bariatric procedures have been approved as the best method to control obesity. However, some patients may experience weight regain or weight loss failure after the initial surgery and require revisional or conversional interventions. In a systematic review of 41 studies involving 1403 patients, it was found that revision procedures can result in significant weight loss after the initial weight loss surgery, with different procedures showing varying effects at different follow-up times. The most effective procedure for long-term weight loss outcomes appeared to be DRGB or BPD-DS/SADI-S. More studies with larger sample sizes and longer follow-up periods are needed to confirm these findings.
UPDATES IN SURGERY
(2021)
Article
Nutrition & Dietetics
Celine Drai, Andrea Chierici, Luigi Schiavo, Tagleb S. Mazahreh, Anne-Sophie Schneck, Antonio Iannelli
Summary: Pouch resizing after Roux-en-Y gastric bypass (RYGB) results in a failure rate of 47% at the 10-year follow-up, while the resolution of comorbidities is maintained over time despite significant weight regain.
Article
Nutrition & Dietetics
Catia Martins, Siren Nymo, Silvia R. Coutinho, Jens F. Rehfeld, Gary R. Hunter, Barbara A. Gower
Summary: The aim of this study was to determine the relationship between % FFML following weight loss and weight regain, as well as the association between % FFML and changes in appetite markers. The results showed that % FFML was not a significant predictor of weight regain at 1 year in individuals with obesity. However, a greater % FFML was associated with a greater increase in ghrelin secretion.
JOURNAL OF NUTRITION
(2023)
Article
Surgery
Marc Beisani, Fatima Sabench Pereferrer, Ramon Vilallonga, Oscar Gonzalez Lopez, Alicia Molina Lopez, Daniel del Castillo Dejardin, Amador Garcia Ruiz de Gordejuela, Jose Manuel Fort Lopez-Barajas, Manel Armengol Carrasco
Summary: This study aimed to replicate the methodology used for determining %AWL and proposed a new metric %MAWL, with results showing that using a reference point of 18 instead of 13 produced initial-weight-independent outcomes in Mediterranean patients.
Article
Endocrinology & Metabolism
Andrew Grannell, William P. Martin, Babak Dehestani, Werd Al-Najim, John C. Murphy, Carel W. le Roux
Summary: This study compared fat-free mass (FFM) loss between successful responders to lifestyle intervention alone and lifestyle intervention plus liraglutide 3.0 mg. It was found that liraglutide led to more weight and FFM loss compared to lifestyle intervention alone. However, after controlling for weight loss, there was no significant difference in FFM loss between the two groups. Exercise did not increase weight loss, and resistance training frequency did not attenuate FFM loss.
Review
Endocrinology & Metabolism
Rutger J. Franken, Josephine Franken, Nina R. Sluiter, Ralph de Vries, Sjoerd Euser, Victor E. A. Gerdes, Maurits de Brauw
Summary: A systematic review and meta-analysis were conducted to evaluate various revisional techniques for addressing weight regain and inadequate weight loss after Roux-en-Y gastric bypass. The results showed that endoscopic procedures resulted in short-term weight loss, while surgical revision techniques were more successful in achieving long-term weight loss, albeit with higher complication rates.
Article
Sport Sciences
Jackson J. Peos, Eric R. Helms, Paul A. Fournier, Julian Ong, Carly Hall, James Krieger, Amanda Sainsbury
Summary: The study found that similar fat loss and fat-free mass retention were achieved with intermittent moderate energy restriction (mIER) and continuous moderate energy restriction (mCER) during 12 weeks of energy restriction, but mIER was associated with reduced appetite.
MEDICINE AND SCIENCE IN SPORTS AND EXERCISE
(2021)
Article
Medicine, General & Internal
Israel Gotsman, Andre Keren, Offer Amir, Donna R. Zwas
Summary: The study found that increased body composition indices, including body mass index, fat-free mass index, and fat mass index, were associated with better survival in patients with heart failure. The strongest association was seen with fat-free mass index, showing a graded increase in survival.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION
(2022)
Review
Surgery
Mohammad Kermansaravi, Radwan Kassir, Rohollah Valizadeh, Chetan Parmar, Amir Hossein Davarpanah Jazi, Shahab Shahabi Shahmiri, Marine Benois
Summary: Complications like leaks after one-anastomosis gastric bypass (OAGB) should be managed properly, but there is limited data and no guidelines for leak management. A systematic review and meta-analysis of 46 studies involving 44,318 OAGB patients found a 1% prevalence of leaks. Surgical strategies varied, but about 62.1% of patients with leaks required additional surgery. The most common procedures for leak management were peritoneal washout and drainage, followed by conversion to Roux-en-Y gastric bypass. The mortality rate related to leaks was 1.95%.
INTERNATIONAL JOURNAL OF SURGERY
(2023)
Article
Multidisciplinary Sciences
Stephen J. Hierons, Kazim Abbas, Amelie I. S. Sobczak, Michela Cerone, Terry K. Smith, Ramzi A. Ajjan, Alan J. Stewart
Summary: Obesity is a complex disease that increases the risk of developing other diseases and health problems. This study found that gastric bypass surgery can reduce weight, improve blood sugar control, and lower cholesterol levels in severely obese patients. Additionally, it was observed that the surgery led to changes in lipid metabolism.
SCIENTIFIC REPORTS
(2022)
Article
Biochemistry & Molecular Biology
Magnoudewa Priscille Pana, Pierre Ayotte, Elhadji Anassour-Laouan-Sidi, Edouard Suhas, Clemence Mahana Iti Gatti, Michel Lucas
Summary: This study aimed to assess changes in plasma concentrations of branched-chain amino acids (BCAA) and aromatic amino acids (AAA) after intervention-induced modifications in fat mass (FM) and fat-free mass (FFM) among French Polynesian adolescents. The results showed that a decrease in fat mass accompanied by an increase in fat-free mass was associated with a significant decrease in concentrations of obesity and insulin resistance metabolic markers.
Article
Surgery
Fatin Abdulsalam, Habiba Ali, Ajda Altinoz, Abdelrahman Nimeri
Summary: This study found that RYGB surgery can significantly preserve muscle mass, while SG patients experienced significant reductions in fat mass and muscle mass at 3 and 12 months. The majority of patients had protein intakes below 60 g/day during the first year after surgery.
Article
Multidisciplinary Sciences
Jean-Claude Pineau, Fernando V. Ramirez Rozzi
Summary: Excess fat is a risk factor for chronic diseases. Predictive equations based on age and sex can estimate body fat mass and percentage. However, their accuracy may vary when applied to different populations. Our study evaluates the generalizability of these equations and finds that only those derived from large sample sizes can accurately estimate fat values.
Article
Surgery
H. J. M. Smelt, S. Van Rijn, S. Pouwels, M. P. W. Aarts, J. F. Smulders
Summary: A longer BPL (biliopancreatic limb) is associated with more %EWL and %TWL 2 years after RYGB. However, it is accompanied by an increase in diarrhea and steatorrhea. Future studies should focus on tailoring BPL and AL lengths for optimal outcomes in morbidly obese patients.
Article
Surgery
Catherine Tsai, Maria Dimou, Markus Naef, Rudolf Steffen, Jorg Zehetner, Christos T. Nakas, Lia Bally
Summary: This study compared the effect of banded and non-banded Roux-en-Y gastric bypass (RYGB) on weight loss over a 5-year follow-up period. The results showed that patients who underwent banded RYGB had a lower risk of insufficient weight loss compared to those who underwent non-banded RYGB. There were no differences in cardiometabolic outcomes between the two groups. Further research is needed to understand the effects of eating behavior restriction and neuroendocrine responses after RYGB.
SURGICAL ENDOSCOPY AND OTHER INTERVENTIONAL TECHNIQUES
(2022)
