Article
Gastroenterology & Hepatology
Emma Rose McGlone, Matthieu Siebert, Marian Dore, David C. D. Hope, Iona Davies, Bryn Owen, Bernard Khoo, Rob Goldin, Dave Carling, Stephen Bloom, Maude Le Gall, Tricia M-M. Tan
Summary: The study investigated the effects of sleeve gastrectomy on weight-independent improvements in liver steatosis in mice with diet-induced obesity. It was found that VSG not only improves liver fat content but also enhances insulin and glucagon sensitivity.
LIVER INTERNATIONAL
(2023)
Article
Multidisciplinary Sciences
Oleg Kornyushin, Dmitry Sonin, Alexander Polozov, Vitaly Masley, Nika Bulavinova, Maria Chervyak, Maria Istomina, Daria Mukhametdinova, Alexander Neimark, Yuri Cheburkin, Yana Toropova, Kira Derkach, Alexander Shpakov, Michael Galagudza, Evgenyi Shlyakhto
Summary: The study showed that bariatric surgery can improve outcomes in patients with myocardial infarction, with Roux-en-Y gastric bypass and sleeve gastrectomy reducing infarct size and no-reflow area. This effect is associated with decreased levels of leptin and ghrelin, and increased levels of GLP-1, enhancing myocardial tolerance to ischemia-reperfusion injury in non-obese, non-diabetic rats.
SCIENTIFIC REPORTS
(2021)
Article
Nutrition & Dietetics
Nora Hedback, Morten Hindso, Kirstine N. Bojsen-Moller, Adelaide K. Linddal, Nils B. Jorgensen, Carsten Dirksen, Andreas Moller, Viggo B. Kristiansen, Bolette Hartmann, Jens J. Holst, Maria S. Svane, Sten Madsbad
Summary: Liquid and solid meals with identical macronutrient composition result in similar postprandial glucose responses, but small differences are observed for the postprandial peaks of certain gut hormones.
FRONTIERS IN NUTRITION
(2022)
Article
Surgery
David E. Arterburn, Eric Johnson, Karen J. Coleman, Lisa J. Herrinton, Anita P. Courcoulas, David Fisher, Robert A. Li, Mary Kay Theis, Liyan Liu, James R. Fraser, Sebastien Haneuse
Summary: Among patients with severe obesity undergoing SG and RYGB, significantly more weight loss was observed at 5 years compared to nonsurgical patients. Weight regain was common after surgery, but regain to within 5% of baseline was rare.
Article
Medicine, General & Internal
Jean-Eric Tarride, Aristithes G. Doumouras, Dennis Hong, J. Michael Paterson, Semra Tibebu, Francis Nguyen, Richard Perez, Valerie H. Taylor, Feng Xie, Vanessa Boudreau, Eleanor Pullenayegum, David R. Urbach, Mehran Anvari
Summary: This study compared 4-year health care expenditures after RYGB and sleeve gastrectomy, finding no significant differences in all-cause mortality and number of hospital admissions between the two procedures, but more frequent nonelective hospitalizations with RYGB. Patients who underwent RYGB had a lower rate of subsequent bariatric procedures.
Article
Gastroenterology & Hepatology
Gontrand Lopez-Nava, Ravishankar Asokkumar, Inmaculada Bautista-Castano, Janese Laster, Anuradha Negi, Stephanie Fook-Chong, Javier Nebreda Duran, Eduard Espinett Coll, Jordi Pujol Gebelli, Amador Garcia Ruiz de Gordejuela
Summary: The study compared the efficacy and safety of endoscopic sleeve gastroplasty (ESG) with laparoscopic sleeve gastrectomy (LSG) and laparoscopic greater curve plication (LGCP) over 2 years. Results showed that although ESG had a slightly lower weight loss rate compared to other techniques, it displayed better safety profile and shorter hospital stay.
Article
Endocrinology & Metabolism
Chongrong Shen, Yanru Chen, Qiaoling Wang, Yingkai Sun, Huibin Lin, Mengshan Ni, Yufei Chen, Ling Zhang, Jiabin Jin, Xiayang Ying, Yuyao Zou, Xiaolin Wang, Yaorui Ye, Miaomiao Yuan, Nan Yin, Zhiwen Cao, Yifei Zhang, Weiqiong Gu, Weiqing Wang, Guang Ning, Jiqiu Wang, Shaoqian Zhao, Jie Hong, Ruixin Liu
Summary: This study investigated the changes in fecal short chain fatty acids (SCFAs) and their association with metabolic benefits after sleeve gastrectomy (SG). The results demonstrated that pre-surgery SCFAs may modify the therapeutic effects of SG, with fecal hexanoate and butyrate being potential modifiers impacting the metabolic benefits.
FRONTIERS IN ENDOCRINOLOGY
(2023)
Article
Nutrition & Dietetics
Luigi Schiavo, Silvana Mirella Aliberti, Pietro Calabrese, Anna Maria Senatore, Lucia Severino, Gerardo Sarno, Antonio Iannelli, Vincenzo Pilone
Summary: Taste perception changes after sleeve gastrectomy (SG), leading to a reduced preference for high-sugar and high-fat foods and an increased preference for low-sugar and low-fat foods. The intake frequency of different food classes also changes after SG.
Article
Surgery
Stefan Wallen, Gustaf Bruze, Johan Ottosson, Claude Marcus, Johan Sundstrom, Eva Szabo, Torsten Olbers, Maria Palmetun-Ekback, Ingmar Naslund, Martin Neovius
Summary: This study aimed to compare the use of opioids in patients with obesity who underwent bariatric surgery versus those who underwent intensive lifestyle modification. The results showed that patients who underwent bariatric surgery had a higher proportion of opioid users and a larger total opioid dose, especially in those who received additional surgery during follow-up.
Review
Endocrinology & Metabolism
Junaid Iqbal, Hui-Xuan Wu, Nan Hu, Ying-Hui Zhou, Long Li, Fen Xiao, Ting Wang, Hong-Li Jiang, Shi-Na Xu, Bi-Ling Huang, Hou-De Zhou
Summary: This study provides an up-to-date systematic review and meta-analysis on the overall weight loss effect of glucagon-like peptide-1 receptor agonists (GLP-1 RA) in adults with obesity and overweight without diabetes mellitus. The results show that GLP-1 RA leads to significant weight loss and improves glycemic control without increasing the risk of hypoglycemia. It also has positive effects on blood pressure and lipid levels.
Article
Surgery
Kelly Winter, Grace E. E. Falk, Joel W. W. Alderson, Karson R. R. Quinn, Stephen D. D. Helmer, Nicholas M. M. Brown
Summary: The study aimed to evaluate the impact of the size and volume of stomach removed during laparoscopic sleeve gastrectomy (SG) on percent total body weight lost (%TBWL). The results showed that there was no association between the volume and weight of stomach resected and %TBWL at 1-year post-operation.
Article
Endocrinology & Metabolism
Farhat Fatima, Joran Hjelmesaeth, Kare Inge Birkeland, Hanne Lovdal Gulseth, Jens Kristoffer Hertel, Marius Svanevik, Rune Sandbu, Milada Cvancarova Smastuen, Bolette Hartmann, Jens Juul Holst, Dag Hofso
Summary: This study compared the effects of RYGB and SG on gastrointestinal hormones and beta-cell function in patients with type 2 diabetes. The results showed that RYGB was associated with greater improvement in beta-cell function and higher postprandial GLP-1 levels compared to SG.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Medicine, General & Internal
Sara Rurgo, Elena Cantone, Marcella Pesce, Eleonora Efficie, Mario Musella, Barbara Polese, Barbara De Conno, Marta Pagliaro, Luisa Seguella, Bruna Guida, Giuseppe Esposito, Giovanni Sarnelli
Summary: This study aimed to evaluate the basic taste identification, induced perception, and pleasantness in normal-weight controls and obese subjects before and after bariatric surgery. The findings revealed that the perception of basic tastes is similar in normal-weight and severely obese subjects. Sleeve-gastrectomy-induced weight loss significantly increases basic taste-induced intensity, and selectively reduces bitter-related pleasantness without affecting the ability to identify the tastes.
JOURNAL OF CLINICAL MEDICINE
(2022)
Article
Nutrition & Dietetics
Federico Carbone, Elisa Nulli Migliola, Aldo Bonaventura, Alessandra Vecchie, Stefano De Vuono, Maria Anastasia Ricci, Gaetano Vaudo, Marcello Boni, Stefano Ministrini, Graziana Lupattelli, Fabrizio Montecucco
Summary: The study found that baseline serum levels of sclerostin are correlated with anthropometric measures of obesity and insulin resistance, particularly with peripheral insulin sensitivity. This suggests a close association between serum sclerostin and glycemic improvements after bariatric surgery.
Review
Gastroenterology & Hepatology
Nele Steenackers, Tim Vanuytsel, Patrick Augustijns, Jan Tack, Ann Mertens, Matthias Lannoo, Bart Van der Schueren, Christophe Matthys
Summary: Sleeve gastrectomy and Roux-en-Y gastric bypass have distinct effects on gastrointestinal physiology, such as accelerating gastric emptying and increasing bile acid serum levels. However, their effects on other aspects remain largely unknown.
LANCET GASTROENTEROLOGY & HEPATOLOGY
(2021)