期刊
OBESITY FACTS
卷 5, 期 1, 页码 91-103出版社
KARGER
DOI: 10.1159/000336077
关键词
Central adiposity; Metabolic syndrome; Maximal power output; Physical fitness; Leptin; Insulin sensitivity
资金
- University Hospital Center through the Regional Direction of Clinical Research (PHRC)
Aim: To compare the maximal power output (MPO) of subjects presenting a central adiposity to those of controls and to study the links between plasma leptin or indices of insulin sensitivity (QUICKI) and physical fitness (PF). Methods: MPO was determined for 169 middle-aged men divided into two groups according to waist circumference (WC- < 94 cm, WC+ >= 94 cm) each subdivided in two subgroups with low and high PF (WC-L, WC-H, WC+ L, WC+ H) determined from the median MPO relative to fat free mass (3.06 W/kg(FFM)). Results: MPO (W/kg(FFM)) was lower in WC+ than in WC-. Expressed relative to fat mass, leptin was lower and QUICKI higher in WC-than in WC+. In WC+ H, leptin and QUICKI were significantly less disturbed than in WC+ L and were independently correlated to MPO (r = -0.36 and r = 0.32 respectively; p < 0.001). In WC+, when visceral perimeter was added to the analysis, the relationships MPO/leptin remained significant but not MPO/QUICKI. Conclusion: The low PF in subjects with abdominal obesity is independently linked to plasma leptin and insulin sensitivity even if leptin and insulin may share common pathways in their peripheral effects. Visceral adiposity participates to the link between MPO and QUICKI, but not between MPO and leptin. Copyright (C) 2012 S. Karger GmbH, Freiburg
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