Article
Multidisciplinary Sciences
Yanmei Wang, Qianxian Wu, Qian Zhou, Yuyu Chen, Xingxing Lei, Yiding Chen, Qiu Chen
Summary: This meta-analysis found that obese individuals have lower baseline levels of circulating acyl ghrelin (AG) and des-acyl ghrelin (DAG), as well as a faster decline in postprandial AG levels. These findings provide important clinical evidence for further investigations into the role of various forms of ghrelin in energy homeostasis.
SCIENTIFIC REPORTS
(2022)
Article
Neurosciences
R. Janet, A. Fournel, M. Fouillen, E. Derrington, B. Corgnet, M. Bensafi, J. C. Dreher
Summary: The study identified the neural circuits involved in regulating food consumption and highlighted how cognitive regulation modulates olfactomotor measures of olfaction, providing insights into how the brain controls appetite within the healthy population.
Article
Behavioral Sciences
Carin Weirich Gallon, Charles Francisco Ferreira, Aline Henz, Carolina Leao Oderich, Maiara Conzatti, Juliana Ritondale Sodre de Castro, Matheus Parmegiani Jahn, Keoma da Silva, Maria Celeste Osorio Wender
Summary: The study found that participants with PMS consumed more calories and carbohydrates during the luteal phase compared to the follicular phase, while this pattern was not observed in participants without PMS. There was a marginal negative relationship between ghrelin levels and calorie intake in the follicular phase of the PMS group, and a negative relationship between ghrelin and leptin levels in the luteal phase of the group without PMS.
Article
Behavioral Sciences
Siamak Beheshti, Hadi Dehestani
Summary: Ghrelin, a peptide primarily secreted from the stomach, has been shown to have a positive impact on memory formation. However, studies have not measured the expression levels of ghrelin or its receptors in the brain during memory formation. This study found that in fear memory formation, mRNA levels of ghrelin significantly increased 24 hours post-training while its receptors were down-regulated; in spatial memory consolidation, ghrelin expression levels remained unchanged but its receptors showed a significant increase 24 hours post-training.
BEHAVIOURAL BRAIN RESEARCH
(2021)
Article
Multidisciplinary Sciences
Paris Will, Elle Merritt, Rob Jenkins, Alan Kingstone
Summary: The research indicates that abstraction diminishes the perceived mind in pictures. Experiments demonstrate that people are perceived as more real and higher in abilities and experiences when presented as pictures rather than as pictures of pictures. Viewers naturally discriminate between different levels of abstraction and are less willing to share resources with more abstracted individuals.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
(2021)
Article
Agriculture, Multidisciplinary
Kentaro Kaneko, Yuki Tokuyama, Eriko Taniguchi, Shimon Abe, Junya Nakato, Hiroshi Iwakura, Masaru Sato, Atsushi Kurabayashi, Hideyuki Suzuki, Akira Ito, Yuki Higuchi, Ryoko Nakayama, Kimiko Uchiyama, Hajime Takahash, Kousaku Ohinata
Summary: In this study, we demonstrated that novel bioactive peptides derived from rice stimulate the secretion of ghrelin, a hormone that promotes appetite. These peptides are produced by the enzymatic digestion of rice endosperm protein with subtilisin. We found that two specific peptides, QAFEPIRSV and TNPWHSPRQGSF, promote the release of acylated ghrelin and named them rice-ghretropins A and B. These peptides also increase food intake and ghrelin concentration in mice.
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
(2023)
Article
Psychiatry
Karim Abdel Aziz, Fadwa Al-Mugaddam, Subi Sugathan, Prashanth Saseedharan, Tarek Jouini, Mohamed Elhassan Elamin, Hamdy Moselhy, Dina Aly El-Gabry, Danilo Arnone, Sherif M. Karam
Summary: This study found that both acylated and total ghrelin levels were significantly reduced in bipolar disorder patients compared to healthy controls, and were positively correlated with markers of illness severity but negatively correlated with prescribed mood stabilizers, weight, and body mass index.
Article
Nutrition & Dietetics
Martina Platzer, Frederike T. Fellendorf, Susanne A. Bengesser, Armin Birner, Nina Dalkner, Carlo Hamm, Melanie Lenger, Alexander Maget, Rene Pilz, Robert Queissner, Bernd Reininghaus, Alexandra Reiter, Harald Mangge, Sieglinde Zelzer, Hans-Peter Kapfhammer, Eva Z. Reininghaus
Summary: This study explores the underlying causes of obesity and weight gain in bipolar disorder, as well as the associations between food craving, clinical parameters, psychotropic medication, and appetite-related hormones. Results show that individuals with bipolar disorder have higher food craving frequencies compared to healthy controls, with a significant negative correlation between food craving and ghrelin levels. Smoking status and age are significantly associated with food craving intensity, and different medication therapies also influence food craving levels.
Review
Nutrition & Dietetics
Maria Seidel, Signe Markmann Jensen, Darren Healy, Aakriti Dureja, Hunna J. Watson, Birgitte Holst, Cynthia M. Bulik, Jan Magnus Sjogren
Summary: Studies on ghrelin levels in anorexia nervosa patients found that all forms of ghrelin increase in the acute stage, with a significant decrease in total ghrelin observed pre-treatment to follow-up. However, total ghrelin levels remain marginally elevated at follow-up, while no treatment effect was observed for acyl ghrelin.
Article
Oncology
Leah Puklin, Brenda Cartmel, Maura Harrigan, Lingeng Lu, Fang-yong Li, Tara Sanft, Melinda L. Irwin
Summary: This study found that weight loss achieved through a lifestyle intervention is associated with higher ghrelin levels in breast cancer survivors, which may be informative for developing sustainable weight loss programming for this population.
Article
Nutrition & Dietetics
Lotte E. Vlug, Patric J. D. Delhanty, Esther G. Neelis, Martin Huisman, Jenny A. Visser, Edmond H. H. M. Rings, Rene M. H. Wijnen, Sjoerd C. J. Nagelkerke, Merit M. Tabbers, Jessie M. Hulst, Barbara A. E. de Koning
Summary: Children with intestinal failure have elevated levels of ghrelin, which may be related to gut starvation. The dose of parenteral nutrition is positively correlated with ghrelin levels.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Rachel Ginieis, Sashie Abeywickrema, Indrawati Oey, Mei Peng
Summary: This study investigates the effects of ghrelin and leptin on olfactory processing. The results show a positive correlation between ghrelin levels and supra-threshold sensitivity and odor intensity, while leptin levels are not significantly linked to any olfactory measures. These findings suggest that ghrelin may play an important role in olfactory perception.
FRONTIERS IN NUTRITION
(2022)
Article
Food Science & Technology
Eva Meersseman, Iris Vermeir, Maggie Geuens
Summary: Consumers are more accustomed to seeing their food from a diner's eye perspective in food pictures, and when viewing top perspective images, they show decreased need for instant gratification and tend to choose less unhealthy food.
FOOD QUALITY AND PREFERENCE
(2021)
Article
Behavioral Sciences
Naomi J. McKay, Nicolas R. Giorgianni, Kristin E. Czajka, Michael G. Brzyski, Cassandra L. Lewandowski, Marnee L. Hales, Isabelle K. Sequeira, Maritess B. Bernardo, Elizabeth G. Mietlicki-Baase
Summary: It is well known that stress can increase total caloric intake, and the hormone ghrelin is the likely candidate driving stress-induced hyperphagia in humans.
HORMONES AND BEHAVIOR
(2021)
Article
Food Science & Technology
Eva Meersseman, Maggie Geuens, Iris Vermeir
Summary: Consumers are more likely to choose unhealthy food when presented with messy food pictures, according to three studies involving 1796 participants. The effect is driven by increased product vividness, which heightens the need for instant gratification. However, this messy food effect is moderated by consumers' orderliness in eating contexts, as those who usually have high levels of orderliness are not affected by messy food pictures in terms of product vividness and unhealthy food choices.
FOOD QUALITY AND PREFERENCE
(2023)
Article
Clinical Neurology
Robert Bodizs, Csenge G. Horvath, Orsolya Szalardy, Peter P. Ujma, Peter Simor, Ferenc Gombos, Ilona Kovacs, Lisa Genzel, Martin Dresler
Summary: The study found that sleep-spindle frequencies decelerate during the night and vary across different age groups. Fine frequency resolution analysis of sleep spindles can be a feasible method for measuring circadian modulation of sleep, with potential implications for assessing chronotype.
JOURNAL OF SLEEP RESEARCH
(2022)
Letter
Psychology, Biological
Martin Dresler, Eva Buddeberg, Ulrike Endesfelder, Jan Haaker, Christian Hof, Robert Kretschmer, Dirk Pfluger, Fabian Schmidt
NATURE HUMAN BEHAVIOUR
(2022)
Article
Neurosciences
Jingyuan Ren, Furong Huang, Chuanji Gao, Jarrod Gott, Sarah F. Schoch, Shaozheng Qin, Martin Dresler, Jing Luo
Summary: This study investigated the impact of novel stimuli on the left and right medial temporal lobes, revealing different activations in response to novel designs of different usefulness. The findings suggest that the left medial temporal lobe is predominantly involved in usefulness processing, while the right medial temporal lobe is predominantly involved in novelty processing. Additionally, the left parahippocampal gyrus showed stronger connectivity with the anterior cingulate cortex when responding to novel useless designs, while the right parahippocampal gyrus showed stronger connectivity with the amygdala, midbrain, and hippocampus.
Article
Neurosciences
Lisa Bastian, Anumita Samanta, Demetrius Ribeiro de Paula, Frederik D. Weber, Robby Schoenfeld, Martin Dresler, Lisa Genzel
Summary: This study investigates the role of fast and slow spindle-slow oscillation coupling in the consolidation of spatial memory in humans and analyzes the evolution of resting-state functional connectivity across learning, consolidation, and retrieval of a virtual watermaze task.
HUMAN BRAIN MAPPING
(2022)
Article
Neurosciences
Maxi Becker, Dimitris Repantis, Martin Dresler, Simone Kuehn
Summary: This study used behavioral and fMRI data to investigate the cognitive enhancement effects of stimulants such as methylphenidate, modafinil, and caffeine. The results showed that these stimulants can enhance memory and modulate functional connectivity between brain networks. Specifically, the frontoparietal network and default mode network were found to be affected, suggesting that these networks play a role in the cognitive enhancement mechanisms of stimulants.
HUMAN BRAIN MAPPING
(2022)
Editorial Material
Neurosciences
Martin Dresler
Summary: Receiving research grants is a highlight of academic career, but the process of acquiring funding is often disliked by many researchers. The current research funding system is inefficient and needs improvement. A simple, fair and widely supported alternative is to distribute funding more equally among researchers and implement quality control through postponed peer review using open science practices.
EUROPEAN JOURNAL OF NEUROSCIENCE
(2022)
Editorial Material
Cell Biology
Martin Dresler, Eva Buddeberg, Ulrike Endesfelder, Jan Haaker, Christian Hof, Robert Kretschmer, Dirk Pflueger, Fabian Schmidt
IMMUNOLOGY AND CELL BIOLOGY
(2023)
Article
Multidisciplinary Sciences
Csenge G. Horvath, Orsolya Szalardy, Peter P. Ujma, Peter Simor, Ferenc Gombos, Ilona Kovacs, Martin Dresler, Robert Bodizs
Summary: Understanding the dynamics of human sleep features during the course of sleep is crucial for sleep regulation. By analyzing sleep records of 251 healthy human subjects, this study reveals the changes in spectral slopes and intercepts during consecutive sleep cycles, which are significant predictors of sleep intensity. The findings suggest that scale-free and oscillatory measures of sleep EEG can provide composite measures of sleep dynamics and offer new insights into sleep regulatory processes.
SCIENTIFIC REPORTS
(2022)
Article
Multidisciplinary Sciences
Sofia Tzioridou, Martin Dresler, Kristian Sandberg, Erik M. Mueller
Summary: This study found an association between mindfulness and nightmares, with mindful acceptance showing a stronger relationship with nightmare frequency and distress. Individuals with high levels of meditation expertise and practice of lucid dream induction techniques reported lower nightmare frequency. In frequent lucid dreamers, there was a positive correlation between lucid dreaming frequency and mindfulness.
SCIENTIFIC REPORTS
(2022)
Article
Mathematical & Computational Biology
Bence Schneider, Orsolya Szalardy, Peter P. Ujma, Peter Simor, Ferenc Gombos, Ilona Kovacs, Martin Dresler, Robert Bodizs
Summary: The power spectra of sleep electroencephalograms (EEG) consist of both a decaying power-law and spectral peaks. Traditional methods ignore this structure and may misrepresent the EEG spectra. The FOOOF method was used to separate and parameterize the components, revealing sleep stage sensitivity and potential indicators of sleep states.
FRONTIERS IN NEUROINFORMATICS
(2022)
Editorial Material
Neurosciences
Jingyuan Ren, Boris N. N. Konrad, Isabella C. C. Wagner, Martin Dresler
EUROPEAN JOURNAL OF NEUROSCIENCE
(2023)
Editorial Material
Clinical Neurology
Somayeh Ataei, Martin Dresler, Sarah F. Schoch
Article
Behavioral Sciences
Mahdad Jafarzadeh Esfahani, Soha Farboud, Hong-Viet V. Ngo, Jules Schneider, Frederik D. Weber, Lucia M. Talamini, Martin Dresler
Summary: Sleep is crucial for our physical and mental well-being, and slow oscillations in the brain play a significant role in sleep functions. By utilizing closed-loop auditory stimulation, researchers can investigate the causal relationship between slow oscillations and sleep functions.
NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
(2023)
Article
Clinical Neurology
Somayeh Ataei, Eni Simo, Mathijs Bergers, Sarah F. Schoch, Nikolai Axmacher, Martin Dresler
Summary: This review provides a comprehensive overview of the history of sleep learning research conducted in humans, synthesizing the findings from 51 research papers. The results suggest that simpler forms of learning, such as habituation and conditioning, may be possible during sleep, while the findings for more complex, applied learning are more divergent. Behavioral evidence for the transfer of new knowledge to wake remains inconclusive, although neural markers often indicate processing and learning during sleep.
SLEEP MEDICINE REVIEWS
(2023)
Article
Multidisciplinary Sciences
Peter P. Ujma, Martin Dresler, Peter Simor, Daniel Fabo, Istvan Ulbert, Lorand Eross, Robert Bodizs
Summary: The envelope spectrum of sleep EEG reflects neuronal firing and can predict age and sex, and its spectrum is associated with demographic and disease-related phenotypes.
SCIENTIFIC REPORTS
(2022)
