Article
Public, Environmental & Occupational Health
Alisa Weiland, Lena Kasemann Nannette, Stephan Zipfel, Stefan Ehehalt, Katrin Ziser, Florian Junne, Isabelle Mack
Summary: This study systematically reviewed the predictors of body weight loss and weight loss maintenance in children and adolescents after behavioral weight loss intervention. The results showed that genetics and blood parameters were significant predictors in physiology, while behavior and environment factors were less investigated.
FRONTIERS IN PUBLIC HEALTH
(2022)
Article
Veterinary Sciences
J. Rebecca Niese, Tierney Mepham, Mirjam Nielen, Evelyn M. Monninkhof, Floor M. Kroese, Denise T. D. de Ridder, Ronald J. Corbee
Summary: The study found that weight loss programs for both dogs and dog owners could mutually promote weight loss between them. The results showed that active weight loss in one party led to passive weight loss in the other during the weight loss process.
FRONTIERS IN VETERINARY SCIENCE
(2021)
Article
Nutrition & Dietetics
Giovanna Flore, Antonio Preti, Mauro Giovanni Carta, Andrea Deledda, Michele Fosci, Antonio Egidio Nardi, Andrea Loviselli, Fernanda Velluzzi
Summary: Only 25% of patients succeed in maintaining the result of weight loss for a long time after a low-calorie diet. This systematic review and meta-analysis find that intensive intervention during the maintenance phase may contribute to greater preservation of weight loss achieved during the previous slimming phase, although the difference from the control group is not statistically significant.
Article
Endocrinology & Metabolism
Carel W. le Roux, Shuyu Zhang, Louis J. Aronne, Robert F. Kushner, Ariana M. Chao, Sriram Machineni, Julia Dunn, Farai B. Chigutsa, Nadia N. Ahmad, Mathijs C. Bunck
Summary: The SURMOUNT development program aims to evaluate the effectiveness and safety of tirzepatide as a treatment for obesity. The program includes four global phase 3 trials, which have shown that once-weekly administration of tirzepatide can significantly reduce body weight.
Article
Endocrinology & Metabolism
Yanyan Dai, Yujuan Li, Shu Yang, Weiwei Xu, Hong Jia, Chao Yang
Summary: Weight change is associated with the risk of metabolic abnormalities. Long-term excessive weight gain is positively associated with an increased risk of metabolic abnormalities in non-overweight/obese individuals, while long-term weight loss is a protective factor for metabolic health in overweight/obese individuals.
FRONTIERS IN ENDOCRINOLOGY
(2022)
Article
Cardiac & Cardiovascular Systems
Camilla F. Thomsen, Tina S. Goharian, Kristian T. Larsen, Jens P. Goetze, Lars B. Andersen, Jorgen L. Jeppesen
Summary: The study demonstrates that an intensive lifestyle intervention increases plasma MR-proANP among overweight children, improving fitness and reducing body mass index.
JOURNAL OF THE AMERICAN HEART ASSOCIATION
(2021)
Article
Medicine, General & Internal
Julie R. Lundgren, Charlotte Janus, Simon B. K. Jensen, Christian R. Juhl, Lisa M. Olsen, Rasmus M. Christensen, Maria S. Svane, Thomas Bandholm, Kirstine N. Bojsen-Moller, Martin B. Blond, Jens-Erik B. Jensen, Bente M. Stallknecht, Jens J. Holst, Sten Madsbad, Signe S. Torekov
Summary: A strategy combining exercise and liraglutide therapy improved healthy weight loss maintenance more than either treatment alone. The combination strategy led to greater weight loss and improvements in metabolic health-related indicators.
NEW ENGLAND JOURNAL OF MEDICINE
(2021)
Review
Nutrition & Dietetics
Audrey Tay, Hannah Hoeksema, Rinki Murphy
Summary: This review analyzed qualitative data to explore the barriers and facilitators of weight loss and weight loss maintenance. Four aggregate themes were identified: internal factors, program-specific factors, social factors, and environmental factors. The findings highlight the importance of considering participant acceptability and engagement in future interventions, and suggest strategies such as tailored interventions, relapse management plans, and strategies to enhance motivation and emotional self-regulation.
Article
Pediatrics
Khen Sela Peremen, Shay Maor, Amit Yaniv, Ishai Aloni, Tomer Ziv-Baran, Gal Dubnov-Raz
Summary: The recommended treatment for children with obesity involves multiple consultations with a multidisciplinary team, which can be burdensome. The use of telehealth has shown potential in providing regular care to children with obesity, but the specific approaches and methods are still being explored. This study compared the changes in BMI and body fat percent over 6 months between participants in a telehealth program and children who received traditional on-site care. After 6 months, a higher percentage of participants in the telehealth group continued treatment compared to the on-site group. Both groups showed significant reductions in BMI, with a similar proportion of reductions. No significant differences were found in the changes in BMI, body fat percent, or fat z-scores between the two groups.
Article
Public, Environmental & Occupational Health
Xi Yang, Kaushik Chattopadhyay, Richard Hubbard, Jia-Lin Li, Li Li, Yi Lin
Summary: A 36-month weight management programme in Ningbo, China showed that participants achieved significant initial weight loss at 3 months and maintained the weight loss during 33-month follow-ups. At 36 months, a certain percentage of participants achieved 5%, 10%, and 15% weight loss. The programme is suggested to benefit overweight and obese adults in reducing body weight and maintaining long-term weight loss.
FRONTIERS IN PUBLIC HEALTH
(2021)
Review
Nutrition & Dietetics
Thea Toft Hansen, Arne Astrup, Anders Sjodin
Summary: The systematic review found that increasing protein intake can have a moderate beneficial effect on body weight management. Additionally, individuals with prediabetes or without obesity risk alleles were found to benefit more from a high-protein diet.
Article
Nutrition & Dietetics
Kristina S. Petersen, Jess Murphy, Jane Whitbread, Peter M. Clifton, Jennifer B. Keogh
Summary: This study found that consuming 35 g of peanuts prior to two main meals per day in the context of an energy-restricted diet can achieve weight loss comparable to a traditional low-fat weight loss diet and can significantly lower blood pressure.
Article
Endocrinology & Metabolism
Joanna MacEwan, Hong Kan, Kevin Chiu, Jiat Ling Poon, Shraddha Shinde, Nadia N. Ahmad
Summary: The study found that despite the availability of newer anti-obesity medications, their utilization remains low in the United States. Users of these medications generally had higher healthcare costs, achieved better weight loss results, while non-users experienced weight gain over the past year. Factors such as depression, dyslipidemia, and infertility predicted the use of anti-obesity medications, while having Medicare coverage and being at risk of sleep apnea were associated with lower odds of usage.
ENDOCRINE PRACTICE
(2021)
Article
Nutrition & Dietetics
Xi Fang, Xue Davis, Kyle D. Flack, Chavonn Duncan, Fangyong Li, Marney White, Carlos Grilo, Dana M. Small
Summary: This study investigates the effect of pre-intervention dietary fat intake on the efficacy of a dietary supplement for weight loss maintenance, highlighting the impact of a high-fat diet on gut-brain signaling pathways. A clinical trial was conducted with 100 adults to assess whether OEA supplementation is moderated by pre-intervention diet and to identify biomarkers that predict response to treatment. The research aims to support precision medicine strategies for weight loss maintenance through targeting the gut-brain axis.
FRONTIERS IN NUTRITION
(2022)
Article
Nutrition & Dietetics
Faidon Magkos, Sidse Rasmussen, Mads F. Hjorth, Sarah Asping, Maria Rosenkrans, Anders M. Sjodin, Arne Astrup, Nina R. W. Geiker
Summary: This study found that healthy diets containing small or large amounts of unprocessed beef had similar effects on body weight, energy metabolism, and cardiovascular risk factors during the first 3 months after clinically significant rapid weight loss.
AMERICAN JOURNAL OF CLINICAL NUTRITION
(2022)
Article
Public, Environmental & Occupational Health
J. Hua, A. S. Mendoza-Vasconez, B. W. Chrisinger, T. L. Conway, M. Todd, M. A. Adams, J. F. Sallis, K. L. Cain, B. E. Saelens, L. D. Frank, A. C. King
Summary: This study used latent profile analysis to assess the impact of the built environment on social cohesion and quality of life among seniors. The results showed that seniors who perceived their neighborhoods to be suitable for walking and recreational activities had higher social cohesion and quality of life.
JOURNAL OF PUBLIC HEALTH
(2022)
Article
Pediatrics
Robert Glenn Weaver, Ethan Hunt, Bridget Armstrong, Michael W. Beets, Keith Brazendale, Gabrielle Turner-McGrievy, Russell R. Pate, Alberto Maydeu-Olivares, Brian Saelens, Shawn D. Youngstedt, Roddrick Dugger, Hannah Parker, Lauren von Klinggraeff, Alexis Jones, Sarah Burkhart, Layton Ressor-Oyer
Summary: Compared to traditional schools, children attending year-round schools had higher BMI gains during the school year, but lower BMI gains and higher cardiorespiratory fitness improvements during the summer. There were observed differences in weight status and race during both summer and school periods. Growth models showed similar overall changes in zBMI and cardiorespiratory fitness from kindergarten to sixth grade for both year-round and traditional school children.
Article
Endocrinology & Metabolism
Kathryn M. Ross, Chelsea A. Carpenter, Kelsey M. Arroyo, Meena N. Shankar, Fan Yi, Peihua Qiu, Lisa Anthony, Jaime Ruiz, Michael G. Perri
Summary: This study found that transitioning from face-to-face to remote delivery during the COVID-19 pandemic did not result in significantly smaller weight losses than those typically observed in gold-standard, face-to-face programs. The results indicate that behavioral weight-management interventions can be effective whether delivered in person or remotely.
Article
Endocrinology & Metabolism
Christian L. Roth, Susan J. Melhorn, Mary Rosalynn B. De Leon, Maya G. Rowland, Clinton T. Elfers, Alyssa Huang, Brian E. Saelens, Ellen A. Schur
Summary: This study investigated the changes in brain activation and hormone levels in response to family-based behavioral treatment (FBT) in children with obesity. The findings suggest that FBT leads to adaptations in central and peripheral satiety responses. While peripheral satiety responses by gut hormones improve after weight loss, the central regulation of satiety remains weaker, which may increase the risk of weight regain.
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
(2022)
Article
Nutrition & Dietetics
Lauren Sawyer, Vanessa M. Oddo, Amanda Fretts, Melissa A. Knox, Nadine Chan, Brian E. Saelens, Jessica C. Jones-Smith
Summary: Research suggests that the implementation of sweetened beverage taxes in Seattle has led to significant increases in lower-income residents' perceptions of the health risks associated with sweetened beverage consumption, particularly regarding diabetes, heart disease, and serious health issues. Conversely, fewer changes were observed among higher-income residents. Further examination could explore the impact of pro-tax messaging on consumer perceptions of sweetened beverages.
Article
Clinical Neurology
Kendra N. Krietsch, Kara M. Duraccio, Nanhua Zhang, Brian E. Saelens, Taylor Howarth, Angela Combs, Dean W. Beebe
Summary: This study examined the impact of altering adolescents' bedtime on their activity levels. The results showed that earlier bedtimes led to longer sleep duration and reduced sedentary behavior and light physical activity, while moderate-to-vigorous physical activity remained unaffected.
Article
Environmental Studies
Behram Wali, Lawrence D. Frank, Deborah R. Young, Brian E. Saelens, Richard T. Meenan, John F. Dickerson, Erin M. Keast, Jennifer L. Kuntz, Stephen P. Fortmann
Summary: This study reveals the connection between urban form, mode-specific physical activity, and healthcare costs, as well as the indirect associations between residential choices, attitudes, and health outcomes. The results suggest that altering behaviors and retrofitting neighborhoods can lead to lower healthcare costs.
ENVIRONMENT AND BEHAVIOR
(2022)
Article
Public, Environmental & Occupational Health
Brian E. Saelens, Richard T. Meenan, Erin M. Keast, Lawrence D. Frank, Deborah R. Young, Jennifer L. Kuntz, John F. Dickerson, Stephen P. Fortmann
Summary: The study found that individuals who use public transit more frequently have lower healthcare costs, especially in total costs and medication costs. Similar results were seen for individuals with low transit use. However, there was no significant difference in outpatient costs among different transit users.
JOURNAL OF TRANSPORT & HEALTH
(2022)
Article
Economics
Richard T. Meenan, Lawrence D. Frank, Brian E. Saelens, Deborah R. Young, Jennifer L. Kuntz, John F. Dickerson, Behram Wali, Erin M. Keast, Stephen P. Fortmann
Summary: This study conducted an interrupted time series analysis to examine the effects of introducing a new light rail transit (LRT) line on health care costs. The results showed that the new LRT did not lower health care costs within the first 4.5 years after its opening. Despite the lack of evidence for transit-related reductions in health care costs, further research into the potential influence of public transit on physical activity and downstream health care costs is still warranted.
Article
Nutrition & Dietetics
Adrian Ortega, Carolina M. Bejarano, Christopher C. Cushing, Vincent S. Staggs, Amy E. Papa, Chelsea Steel, Robin P. Shook, Terry L. Conway, Brian E. Saelens, Karen Glanz, Kelli L. Cain, Lawrence D. Frank, Jacqueline Kerr, Jasper Schipperijn, James F. Sallis, Jordan A. Carlson
Summary: The purpose of this study was to investigate the relationship between psychosocial and environmental variables and physical activity and sedentary time in different locations among adolescents. The results showed that psychosocial and environmental indices related to physical activity were specific to certain locations, such as school and home. These findings suggest that the influence of psychosocial and environmental factors on physical activity varies across different locations.
INTERNATIONAL JOURNAL OF BEHAVIORAL NUTRITION AND PHYSICAL ACTIVITY
(2022)
Article
Biochemistry & Molecular Biology
Dylan L. Steen, Robert N. Helsley, Deepak L. Bhatt, Eileen C. King, Suzanne S. Summer, Matthew Fenchel, Brian E. Saelens, Mark H. Eckman, Sarah C. Couch
Summary: This study demonstrates the effectiveness of data-guided, supermarket-based dietary interventions and modern online shopping tools in improving dietary quality in a free-living, community-based population. It also highlights the opportunity for academic researchers to collaborate with retailers in designing and rigorously testing comprehensive healthcare interventions.
Article
Public, Environmental & Occupational Health
B. E. Saelens, P. M. Hurvitz, C. Zhou, T. Colburn, A. Marchese, A. Moudon
Summary: This study examines the impact of living close or far away from new transit options on transit use and physical activity. The results indicate that the opening of a new light rail line did not significantly change the frequency of transit use among nearby residents, but did result in a small increase in transit-related walking.
JOURNAL OF TRANSPORT & HEALTH
(2022)
Article
Endocrinology & Metabolism
Kathryn M. Ross, Lu You, Peihua Qiu, Meena N. Shankar, Taylor N. Swanson, Jaime Ruiz, Lisa Anthony, Michael G. Perri
Summary: The objective of this study was to develop a predictive algorithm for identifying high-risk periods for weight regain after weight loss. The algorithm was developed using longitudinal mixed-effects models and random forest regression, based on weekly questionnaire and self-monitoring data collected from 46 adults over a period of 40 weeks. The algorithm was evaluated in two separate studies and showed promising results in predicting weight regain on a weekly basis.
Article
Multidisciplinary Sciences
Courtney M. Hill, Donald L. Chi, Lloyd A. Mancl, Jessica C. Jones-Smith, Nadine Chan, Brian E. Saelens, Christy M. Mckinney
Summary: This study examines the relationship between food insecurity and tooth decay in lower-income children, finding that sugar-sweetened beverage intake and frequent convenience store shopping mediate this relationship. The results suggest that reducing intake of sugar-sweetened beverages and improving access to healthy foods in lower-income communities may help address oral health disparities in children in food-insecure households.
Article
Public, Environmental & Occupational Health
Amal Saleh, Brian Saelens, Maxine Hayes, Tumaini R. Coker
Summary: Community engagement is important for increasing the relevance of research for underserved populations and promoting diversity in research participation. The Community Partnership Guide provides tools for community organizations to decide on research collaborations, step-by-step guidance for engaging with academic investigators, and a template for a memorandum of understanding.
PROGRESS IN COMMUNITY HEALTH PARTNERSHIPS-RESEARCH EDUCATION AND ACTION
(2022)